{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,2]],"date-time":"2026-10-02T03:28:19Z","timestamp":1790911699236,"version":"4.1.0"},"reference-count":24,"publisher":"American Society for Microbiology","issue":"11","license":[{"start":{"date-parts":[[1999,11,1]],"date-time":"1999-11-01T00:00:00Z","timestamp":941414400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["Antimicrob Agents Chemother"],"published-print":{"date-parts":[[1999,11]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n          <jats:p>\n            The in vitro antimicrobial susceptibilities of isolates of\n            <jats:italic>Burkholderia mallei<\/jats:italic>\n            to 16 antibiotics were assessed and compared with the susceptibilities of\n            <jats:italic>Burkholderia pseudomallei<\/jats:italic>\n            and\n            <jats:italic>Burkholderia cepacia<\/jats:italic>\n            . The antibiotic susceptibility profile of\n            <jats:italic>B. mallei<\/jats:italic>\n            resembled that of\n            <jats:italic>B. pseudomallei<\/jats:italic>\n            more closely than that of\n            <jats:italic>B. cepacia<\/jats:italic>\n            , which corresponds to their similarities in terms of biochemistry, antigenicity, and pathogenicity. Ceftazidime, imipenem, doxycycline, and ciprofloxacin were active against both\n            <jats:italic>B. mallei<\/jats:italic>\n            and\n            <jats:italic>B. pseudomallei<\/jats:italic>\n            . Gentamicin was active against\n            <jats:italic>B. mallei<\/jats:italic>\n            but not against\n            <jats:italic>B. pseudomallei<\/jats:italic>\n            . Antibiotics clinically proven to be effective in the treatment of melioidosis may therefore be effective for treating glanders.\n          <\/jats:p>","DOI":"10.1128\/aac.43.11.2773","type":"journal-article","created":{"date-parts":[[2018,10,9]],"date-time":"2018-10-09T00:33:39Z","timestamp":1539045219000},"page":"2773-2775","update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":59,"title":["In Vitro Susceptibilities of\n            <i>Burkholderia mallei<\/i>\n            in Comparison to Those of Other Pathogenic\n            <i>Burkholderia<\/i>\n            spp"],"prefix":"10.1128","volume":"43","author":[{"given":"D. J.","family":"Kenny","sequence":"first","affiliation":[{"name":"<!--label omitted: 1-->CBD Porton Down, Salisbury, Wilts SP4 OJQ, United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P.","family":"Russell","sequence":"additional","affiliation":[{"name":"<!--label omitted: 1-->CBD Porton Down, Salisbury, Wilts SP4 OJQ, United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D.","family":"Rogers","sequence":"additional","affiliation":[{"name":"<!--label omitted: 1-->CBD Porton Down, Salisbury, Wilts SP4 OJQ, United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S. M.","family":"Eley","sequence":"additional","affiliation":[{"name":"<!--label omitted: 1-->CBD Porton Down, Salisbury, Wilts SP4 OJQ, United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R. W.","family":"Titball","sequence":"additional","affiliation":[{"name":"<!--label omitted: 1-->CBD Porton Down, Salisbury, Wilts SP4 OJQ, United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"235","reference":[{"key":"e_1_3_1_2_2","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1016\/0147-9571(89)90003-9","article-title":"In vitro susceptibility of Pseudomonas mallei to antimicrobial agents.","volume":"12","author":"Al-Izzi S. A.","year":"1989","unstructured":"Al-Izzi S. A. Al-Bassam L. S. In vitro susceptibility of Pseudomonas mallei to antimicrobial agents. Comp. Immunol. Microbiol. Infect. Dis. 12 1989 5 8","journal-title":"Comp. Immunol. Microbiol. Infect. Dis."},{"key":"e_1_3_1_3_2","unstructured":"Amsterdam\n              D.\n          Susceptibility testing of antimicrobials in liquid media\n          Antibiotics in laboratory medicine\n          4th ed.\n              Lorian\n              V.\n          1996\n          52\n          111\n          Williams & Wilkins\n          Baltimore Md"},{"key":"e_1_3_1_4_2","first-page":"14","article-title":"Sensitivity of Pseudomonas to currently used antibacterial drugs.","volume":"36","author":"Antonov I. V.","year":"1991","unstructured":"Antonov I. V. Sensitivity of Pseudomonas to currently used antibacterial drugs. Antibiot. Khimioter. 36 1991 14 16","journal-title":"Antibiot. Khimioter."},{"key":"e_1_3_1_5_2","first-page":"31","article-title":"Sensitivity of Pseudomonas mallei to fluoroquinolones and their efficacy in experimental glanders.","volume":"36","author":"Batmanov V. P.","year":"1991","unstructured":"Batmanov V. P. Sensitivity of Pseudomonas mallei to fluoroquinolones and their efficacy in experimental glanders. Antibiot. Khimioter. 36 1991 31 34","journal-title":"Antibiot. Khimioter."},{"key":"e_1_3_1_6_2","first-page":"18","article-title":"Treatment of experimental glanders with combinations of sulfazine or sulfamonomethoxine with trimethoprim.","volume":"38","author":"Batmanov V. P.","year":"1993","unstructured":"Batmanov V. P. Treatment of experimental glanders with combinations of sulfazine or sulfamonomethoxine with trimethoprim. Antibiot. Khimioter. 38 1993 18 22","journal-title":"Antibiot. Khimioter."},{"key":"e_1_3_1_7_2","first-page":"33","article-title":"Sensitivity of Pseudomonas mallei to tetracyclines and their effectiveness in experimental glanders.","volume":"39","author":"Batmanov V. P.","year":"1994","unstructured":"Batmanov V. P. Sensitivity of Pseudomonas mallei to tetracyclines and their effectiveness in experimental glanders. Antibiot. Khimioter. 39 1994 33 37","journal-title":"Antibiot. Khimioter."},{"key":"e_1_3_1_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0035-9203(97)90044-4"},{"key":"e_1_3_1_9_2","unstructured":"Cohen\n              J.\n          Septicaemia\n          Antibiotics and chemotherapy\n          7th ed.\n              O\u2019Grady\n              F.\n              Lambert\n              H. P.\n              Finch\n              R. G.\n              Greenwood\n              D.\n          1997\n          588\n          Churchill Livingstone\n          New York N.Y"},{"key":"e_1_3_1_10_2","doi-asserted-by":"publisher","DOI":"10.1128\/CMR.4.1.52"},{"key":"e_1_3_1_11_2","doi-asserted-by":"publisher","DOI":"10.1093\/jac\/24.3.295"},{"key":"e_1_3_1_12_2","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1093\/jac\/28.2.321","article-title":"Development of resistance to ceftazidime and co-amoxyclav in Pseudomonas pseudomallei.","volume":"28","author":"Dance D. A. B.","year":"1991","unstructured":"Dance D. A. B. Wuthiekanun V. Chaowagul W. Suputtamongkol Y. White N. J. Development of resistance to ceftazidime and co-amoxyclav in Pseudomonas pseudomallei. J. Antimicrob. Chemother. 28 1991 321 324","journal-title":"J. Antimicrob. Chemother."},{"key":"e_1_3_1_13_2","first-page":"331","article-title":"Pulmonary melioidosis: observations in thirty-nine cases.","volume":"112","author":"Everett E. D.","year":"1975","unstructured":"Everett E. D. Nelson R. A. Pulmonary melioidosis: observations in thirty-nine cases. Am. Rev. Respir. Dis. 112 1975 331 340","journal-title":"Am. Rev. Respir. Dis."},{"key":"e_1_3_1_14_2","unstructured":"Gerding\n              D. N.\n              Hughes\n              C. E.\n              Bamberger\n              D. M.\n              Foxworth\n              J.\n              Larson\n              T. A.\n          Extravascular antimicrobial distribution and the respective blood concentrations in humans\n          Antibiotics in laboratory medicine\n          4th ed.\n              Lorian\n              V.\n          1996\n          835\n          899\n          Williams & Wilkins\n          Baltimore Md"},{"key":"e_1_3_1_15_2","unstructured":"Holmes\n              A.\n              Jiang\n              R.-Z.\n              Sun\n              L.\n              Steinbach\n              S.\n              Nolan\n              R.\n              Riley\n              M.\n              Goldstein\n              R.\n          Emergence of epidemic strains of Burkholderia cepacia involving both CF and non-CF populations abstr. J32\n          Abstracts of the 36th Interscience Conference on Antimicrobial Agents and Chemotherapy.\n          1996\n          224\n          American Society for Microbiology\n          Washington D.C."},{"key":"e_1_3_1_16_2","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/124.6.598"},{"key":"e_1_3_1_17_2","first-page":"142","article-title":"Study of the bacteriostatic and bactericidal properties of certain antibiotics.","volume":"61","author":"Ipatenko N. G.","year":"1972","unstructured":"Ipatenko N. G. Study of the bacteriostatic and bactericidal properties of certain antibiotics. Tr. Mosk. Vet. Akad. 61 1972 142 148","journal-title":"Tr. Mosk. Vet. Akad."},{"key":"e_1_3_1_18_2","doi-asserted-by":"publisher","DOI":"10.1128\/iai.64.3.782-790.1996"},{"key":"e_1_3_1_19_2","first-page":"26","article-title":"The efficacy of antibacterial preparations against Pseudomonas mallei in in-vitro and in-vivo experiments.","volume":"39","author":"Manzeniuk I. N.","year":"1994","unstructured":"Manzeniuk I. N. The efficacy of antibacterial preparations against Pseudomonas mallei in in-vitro and in-vivo experiments. Antibiot. Khimioter. 39 1994 26 30","journal-title":"Antibiot. Khimioter."},{"key":"e_1_3_1_20_2","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1016\/S0368-1742(04)80089-4","article-title":"Glanders.","volume":"17","author":"MF\u0300adyean J.","year":"1904","unstructured":"MF\u0300adyean J. Glanders. J. Comp. Pathol. 17 1904 295 317","journal-title":"J. Comp. Pathol."},{"key":"e_1_3_1_21_2","unstructured":"National Committee for Clinical Laboratory Standards\n          Methods for dilution antimicrobial susceptibility tests for bacteria that grow aerobically\n          3rd ed.\n          1993 Approved standard M7-A3. National Committee for Clinical Laboratory Standards Villanova Pa."},{"key":"e_1_3_1_22_2","unstructured":"Sanford\n              J. P.\n          Pseudomonas species (including melioidosis and glanders)\n          Principles and practice of infectious diseases\n          4th ed.\n              Mandell\n              G. L.\n              Bennett\n              J. A.\n              Dolin\n              R.\n          1995\n          2003\n          2009\n          Churchill Livingstone\n          New York N.Y"},{"key":"e_1_3_1_23_2","doi-asserted-by":"crossref","first-page":"611","DOI":"10.1093\/jac\/37.3.611","article-title":"In-vitro activity of carbapenem antibiotics against \u03b2-lactam susceptible and resistant strains of Burkholderia pseudomallei.","volume":"64","author":"Smith M. D.","year":"1996","unstructured":"Smith M. D. Wuthiekanun V. Walsh A. L. White N. J. In-vitro activity of carbapenem antibiotics against \u03b2-lactam susceptible and resistant strains of Burkholderia pseudomallei. J. Antimicrob. Chemother. 64 1996 611 615","journal-title":"J. Antimicrob. Chemother."},{"key":"e_1_3_1_24_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(89)90768-X"},{"key":"e_1_3_1_25_2","unstructured":"Wiedemann\n              B.\n              Grimm\n              H.\n          Susceptibility to antibiotics: species incidence and trends\n          Antibiotics in laboratory medicine\n          4th ed.\n              Lorian\n              V.\n          1996\n          900\n          1168\n          Williams & Wilkins\n          Baltimore Md"}],"container-title":["Antimicrobial Agents and Chemotherapy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/AAC.43.11.2773","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/AAC.43.11.2773","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,2,21]],"date-time":"2022-02-21T15:55:22Z","timestamp":1645458922000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.asm.org\/doi\/10.1128\/AAC.43.11.2773"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1999,11]]},"references-count":24,"journal-issue":{"issue":"11","published-print":{"date-parts":[[1999,11]]}},"alternative-id":["10.1128\/AAC.43.11.2773"],"URL":"https:\/\/doi.org\/10.1128\/aac.43.11.2773","relation":{},"ISSN":["0066-4804","1098-6596"],"issn-type":[{"value":"0066-4804","type":"print"},{"value":"1098-6596","type":"electronic"}],"subject":[],"published":{"date-parts":[[1999,11]]},"assertion":[{"value":"1998-11-05","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"1999-08-18","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"1999-11-01","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}