{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,16]],"date-time":"2026-07-16T08:40:30Z","timestamp":1784191230008,"version":"3.55.0"},"reference-count":26,"publisher":"American Society for Microbiology","issue":"3","license":[{"start":{"date-parts":[[1999,3,1]],"date-time":"1999-03-01T00:00:00Z","timestamp":920246400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["Antimicrob Agents Chemother"],"published-print":{"date-parts":[[1999,3]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n          <jats:p>\n            Doses of 10 to 100 mg of the azole antifungal agent SCH 56592\/kg of body weight\/day were studied in immunocompetent mice as therapy for systemic infection by\n            <jats:italic>Fusarium solani<\/jats:italic>\n            . Treatment was begun 1 h after intravenous infection and continued daily for 4 or 13 doses. Prolongation of survival and organ clearance were dependent on both the dose and the duration of SCH 56592 therapy, with the best results seen at 50 and 100 mg\/kg\/day. The results at the highest doses of SCH 56592 used (50 or 100 mg\/kg\/day) were comparable to those obtained with amphotericin B at 1 mg\/kg\/day. SCH 56592 has potential for therapy of systemic infections caused by\n            <jats:italic>F. solani<\/jats:italic>\n            .\n          <\/jats:p>","DOI":"10.1128\/aac.43.3.589","type":"journal-article","created":{"date-parts":[[2018,10,9]],"date-time":"2018-10-09T00:34:19Z","timestamp":1539045259000},"page":"589-591","update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":53,"title":["Treatment of Murine Fusariosis with SCH 56592"],"prefix":"10.1128","volume":"43","author":[{"given":"M.","family":"Lozano-Chiu","sequence":"first","affiliation":[{"name":"<!--label omitted: 1-->Division of Infectious Diseases, Department of Internal Medicine, Center for the Study of Emerging and Reemerging Pathogens, University of Texas Medical School, Houston, Texas 770301;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.","family":"Arikan","sequence":"additional","affiliation":[{"name":"<!--label omitted: 1-->Division of Infectious Diseases, Department of Internal Medicine, Center for the Study of Emerging and Reemerging Pathogens, University of Texas Medical School, Houston, Texas 770301;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"V. L.","family":"Paetznick","sequence":"additional","affiliation":[{"name":"<!--label omitted: 1-->Division of Infectious Diseases, Department of Internal Medicine, Center for the Study of Emerging and Reemerging Pathogens, University of Texas Medical School, Houston, Texas 770301;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"E. J.","family":"Anaissie","sequence":"additional","affiliation":[{"name":"<!--label omitted: 2-->The Myeloma and Transplantation Research Center, University of Arkansas for Medical Sciences, Little Rock, Arkansas 772052; and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D.","family":"Loebenberg","sequence":"additional","affiliation":[{"name":"<!--label omitted: 3-->Schering-Plough Research Institute, Kenilworth, New Jersey3"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J. H.","family":"Rex","sequence":"additional","affiliation":[{"name":"<!--label omitted: 1-->Division of Infectious Diseases, Department of Internal Medicine, Center for the Study of Emerging and Reemerging Pathogens, University of Texas Medical School, Houston, Texas 770301;"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"235","reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1097\/00005792-198803000-00001","article-title":"The emerging role of Fusarium infections in patients with cancer.","volume":"67","author":"Anaissie E.","year":"1988","unstructured":"Anaissie E. Kantarjian H. Ro J. Hopfer R. Rolston K. Fainstein V. Bodey G. The emerging role of Fusarium infections in patients with cancer. 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