{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,11]],"date-time":"2025-11-11T12:33:33Z","timestamp":1762864413754},"reference-count":31,"publisher":"American Society for Microbiology","issue":"12","license":[{"start":{"date-parts":[[2000,12,1]],"date-time":"2000-12-01T00:00:00Z","timestamp":975628800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["Antimicrob Agents Chemother"],"published-print":{"date-parts":[[2000,12]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n          <jats:p>\n            To understand quinupristin-dalfopristin resistance among clinical isolates of gram-positive bacteria in Taiwan, where this agent is not yet available for clinical use, we evaluated 1,287 nonduplicate isolates recovered from January 1996 to December 1999 for in vitro susceptibility to quinupristin-dalfopristin and other newer antimicrobial agents. All methicillin-susceptible\n            <jats:italic>Staphylococcus aureus<\/jats:italic>\n            (MSSA) isolates were susceptible to quinupristin-dalfopristin. High rates of nonsusceptibility to quinupristin-dalfopristin (MICs, \u22652 \u03bcg\/ml) were demonstrated for the following organisms: methicillin-resistant\n            <jats:italic>S. aureus<\/jats:italic>\n            (MRSA) (31%), coagulase-negative staphylococci (CoNS) (16%),\n            <jats:italic>Streptococcus pneumoniae<\/jats:italic>\n            (8%), viridans group streptococci (51%), vancomycin-susceptible enterococci (85%), vancomycin-resistant\n            <jats:italic>Enterococcus faecalis<\/jats:italic>\n            (100%), vancomycin-resistant\n            <jats:italic>Enterococcus faecium<\/jats:italic>\n            (66%),\n            <jats:italic>Leuconostoc<\/jats:italic>\n            spp. (100%),\n            <jats:italic>Lactobacillus<\/jats:italic>\n            spp. (50%), and\n            <jats:italic>Pediococcus<\/jats:italic>\n            spp. (87%). All isolates of MSSA, MRSA,\n            <jats:italic>S. pneumoniae<\/jats:italic>\n            , and viridans group streptococci were susceptible to vancomycin and teicoplanin. The rates of nonsusceptibility to vancomycin and teicoplanin were 5 and 7%, respectively, for CoNS, ranging from 12 and 18% for\n            <jats:italic>S. simulans<\/jats:italic>\n            to 0 and 0% for\n            <jats:italic>S. cohnii<\/jats:italic>\n            and\n            <jats:italic>S. auricularis<\/jats:italic>\n            . Moxifloxacin and trovafloxacin had good activities against these isolates except for ciprofloxacin-resistant vancomycin-resistant enterococci and methicillin-resistant staphylococci. In Taiwan, virginiamycin has been used in animal husbandry for more than 20 years, which may contribute to the high rates of quinupristin-dalfopristin resistance.\n          <\/jats:p>","DOI":"10.1128\/aac.44.12.3374-3380.2000","type":"journal-article","created":{"date-parts":[[2002,7,27]],"date-time":"2002-07-27T10:06:42Z","timestamp":1027764402000},"page":"3374-3380","update-policy":"http:\/\/dx.doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":68,"title":["Quinupristin-Dalfopristin Resistance among Gram-Positive Bacteria in Taiwan"],"prefix":"10.1128","volume":"44","author":[{"given":"Kwen-Tay","family":"Luh","sequence":"first","affiliation":[{"name":"<!--label omitted: 1-->Departments of Laboratory Medicine1and"},{"name":"<!--label omitted: 2-->Internal Medicine,2"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Po-Ren","family":"Hsueh","sequence":"additional","affiliation":[{"name":"<!--label omitted: 1-->Departments of Laboratory Medicine1and"},{"name":"<!--label omitted: 2-->Internal Medicine,2"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lee-Jene","family":"Teng","sequence":"additional","affiliation":[{"name":"<!--label omitted: 1-->Departments of Laboratory Medicine1and"},{"name":"<!--label omitted: 3-->National Taiwan University Hospital, School of Medical Technology, National Taiwan University College of Medicine,3 and"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hui-Ju","family":"Pan","sequence":"additional","affiliation":[{"name":"<!--label omitted: 1-->Departments of Laboratory Medicine1and"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yu-Chi","family":"Chen","sequence":"additional","affiliation":[{"name":"<!--label omitted: 1-->Departments of Laboratory Medicine1and"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jang-Jih","family":"Lu","sequence":"additional","affiliation":[{"name":"<!--label omitted: 4-->Department of Pathology, Tri-Service General Hospital, Taipei,4 and"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jiunn-Jong","family":"Wu","sequence":"additional","affiliation":[{"name":"<!--label omitted: 5-->Department of Medical Technology, National Cheng-Kung University Hospital, Tainan,5 Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shen-Wu","family":"Ho","sequence":"additional","affiliation":[{"name":"<!--label omitted: 1-->Departments of Laboratory Medicine1and"},{"name":"<!--label omitted: 3-->National Taiwan University Hospital, School of Medical Technology, National Taiwan University College of Medicine,3 and"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"235","reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0732-8893(98)00129-1"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9343(78)90521-1"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0732-8893(96)00123-X"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.1086\/313597"},{"key":"e_1_3_2_6_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.37.3.598"},{"key":"e_1_3_2_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/0195-6701(87)90025-9"},{"key":"e_1_3_2_8_2","unstructured":"Facklam\n              R. 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R.\n              Baron\n              E. J.\n              Pfaller\n              M. A.\n              Tenover\n              F. C.\n              Yolken\n              R. H.\n          1999\n          306\n          315\n          American Society for Microbiology\n          Washington D.C."},{"key":"e_1_3_2_28_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.44.2.433-436.2000"},{"key":"e_1_3_2_29_2","doi-asserted-by":"publisher","DOI":"10.1093\/jac\/41.6.621"},{"key":"e_1_3_2_30_2","first-page":"401","article-title":"Association between quinupristin\/dalfopristin resistance in glycopeptide-resistant Enterococcus faecium and the use of additives in animal feed.","volume":"17","author":"Werner G.","year":"1998","unstructured":"Werner G. Klare I. Witte W. Association between quinupristin\/dalfopristin resistance in glycopeptide-resistant Enterococcus faecium and the use of additives in animal feed. Eur. J. Clin. Microbiol. Infect. Dis. 17 1998 401 402","journal-title":"Eur. J. 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