{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,31]],"date-time":"2025-10-31T21:38:05Z","timestamp":1761946685646},"reference-count":9,"publisher":"American Society for Microbiology","issue":"10","license":[{"start":{"date-parts":[[2001,10,1]],"date-time":"2001-10-01T00:00:00Z","timestamp":1001894400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["Antimicrob Agents Chemother"],"published-print":{"date-parts":[[2001,10]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n          <jats:p>\n            The in vitro activities of ABT-773, azithromycin, erythromycin, and clindamycin were compared by testing 1,223 clinical isolates selected to represent different species and phenotypes. ABT-773 was particularly potent against staphylococci (the MIC at which 90% of the strains tested were inhibited [MIC\n            <jats:sub>90<\/jats:sub>\n            ] was \u22640.06 \u03bcg\/ml), including all strains that were macrolide resistant but clindamycin susceptible.\n            <jats:italic>Streptococcus pneumoniae<\/jats:italic>\n            and other streptococci were inhibited by low concentrations of ABT-773, and that included most erythromycin-resistant strains. Against\n            <jats:italic>Haemophilus influenzae<\/jats:italic>\n            , ABT-773 and azithromycin were similar in their antibacterial potency (MIC\n            <jats:sub>90<\/jats:sub>\n            , 4.0 and 2.0 \u03bcg\/ml, respectively).\n          <\/jats:p>","DOI":"10.1128\/aac.45.10.2922-2924.2001","type":"journal-article","created":{"date-parts":[[2002,7,27]],"date-time":"2002-07-27T10:06:42Z","timestamp":1027764402000},"page":"2922-2924","update-policy":"http:\/\/dx.doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":14,"title":["In Vitro Activity of the Ketolide ABT-773"],"prefix":"10.1128","volume":"45","author":[{"given":"Arthur L.","family":"Barry","sequence":"first","affiliation":[{"name":"<!--label omitted: 1-->The Clinical Microbiology Institute, Wilsonville, Oregon 97070"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Peter C.","family":"Fuchs","sequence":"additional","affiliation":[{"name":"<!--label omitted: 1-->The Clinical Microbiology Institute, Wilsonville, Oregon 97070"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Steven D.","family":"Brown","sequence":"additional","affiliation":[{"name":"<!--label omitted: 1-->The Clinical Microbiology Institute, Wilsonville, Oregon 97070"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"235","reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1093\/jac\/46.6.1017"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1469-0691.2000.00152.x"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.42.8.2138"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.42.4.945"},{"key":"e_1_3_2_6_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.44.6.1562-1567.2000"},{"key":"e_1_3_2_7_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.44.7.1894-1899.2000"},{"key":"e_1_3_2_8_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.44.9.2525-2529.2000"},{"key":"e_1_3_2_9_2","unstructured":"National Committee for Clinical Laboratory Standards\n          Methods for dilution antimicrobial susceptibility testing for bacteria that grow aerobically. Approved standard M7\u2013A5.\n          2000\n          NCCLS\n          Wayne Pa"},{"key":"e_1_3_2_10_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.40.8.1817"}],"container-title":["Antimicrobial Agents and Chemotherapy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/AAC.45.10.2922-2924.2001","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/AAC.45.10.2922-2924.2001","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,2,21]],"date-time":"2022-02-21T16:48:43Z","timestamp":1645462123000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.asm.org\/doi\/10.1128\/AAC.45.10.2922-2924.2001"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2001,10]]},"references-count":9,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2001,10]]}},"alternative-id":["10.1128\/AAC.45.10.2922-2924.2001"],"URL":"https:\/\/doi.org\/10.1128\/aac.45.10.2922-2924.2001","relation":{},"ISSN":["0066-4804","1098-6596"],"issn-type":[{"value":"0066-4804","type":"print"},{"value":"1098-6596","type":"electronic"}],"subject":[],"published":{"date-parts":[[2001,10]]},"assertion":[{"value":"2001-03-19","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2001-07-03","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2001-10-01","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}