{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,2]],"date-time":"2026-10-02T03:56:09Z","timestamp":1790913369097,"version":"4.1.0"},"reference-count":16,"publisher":"American Society for Microbiology","issue":"12","license":[{"start":{"date-parts":[[2001,12,1]],"date-time":"2001-12-01T00:00:00Z","timestamp":1007164800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["Antimicrob Agents Chemother"],"published-print":{"date-parts":[[2001,12]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n          <jats:p>\n            The in vitro activity of a novel oxazolidinone, linezolid, was studied by comparing the activity of linezolid with those of amikacin, trimethoprim-sulfamethoxazole, and amoxicillin-clavulanic acid against 25 strains of\n            <jats:italic>Nocardia brasiliensis<\/jats:italic>\n            isolated from patients with mycetoma. All\n            <jats:italic>N. brasiliensis<\/jats:italic>\n            strains tested were sensitive to linezolid (MIC at which 90% of strains are inhibited [MIC\n            <jats:sub>90<\/jats:sub>\n            ], 2 \u03bcg\/ml; MIC\n            <jats:sub>50<\/jats:sub>\n            , 1 \u03bcg\/ml). This antimicrobial might constitute a good alternative for treatment of actinomycetoma.\n          <\/jats:p>","DOI":"10.1128\/aac.45.12.3629-3630.2001","type":"journal-article","created":{"date-parts":[[2002,7,27]],"date-time":"2002-07-27T10:06:42Z","timestamp":1027764402000},"page":"3629-3630","update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":40,"title":["In Vitro Activity of PNU-100766 (Linezolid), a New Oxazolidinone Antimicrobial, against\n            <i>Nocardia brasiliensis<\/i>"],"prefix":"10.1128","volume":"45","author":[{"given":"Lucio","family":"Vera-Cabrera","sequence":"first","affiliation":[{"name":"<!--label omitted: 1-->Laboratorio Interdisciplinario de Investigacio\u0301n Dermatolo\u0301gica, Servicio de Dermatologia, Hospital Universitario, Monterrey, N.L., Me\u0301xico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alejandra","family":"Go\u0301mez-Flores","sequence":"additional","affiliation":[{"name":"<!--label omitted: 1-->Laboratorio Interdisciplinario de Investigacio\u0301n Dermatolo\u0301gica, Servicio de Dermatologia, Hospital Universitario, Monterrey, N.L., Me\u0301xico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wendy G.","family":"Escalante-Fuentes","sequence":"additional","affiliation":[{"name":"<!--label omitted: 1-->Laboratorio Interdisciplinario de Investigacio\u0301n Dermatolo\u0301gica, Servicio de Dermatologia, Hospital Universitario, Monterrey, N.L., Me\u0301xico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Oliverio","family":"Welsh","sequence":"additional","affiliation":[{"name":"<!--label omitted: 1-->Laboratorio Interdisciplinario de Investigacio\u0301n Dermatolo\u0301gica, Servicio de Dermatologia, Hospital Universitario, Monterrey, N.L., Me\u0301xico"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"235","reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.44.5.1367-1369.2000"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.2165\/00003495-200059040-00007"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.43.5.1189"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.2165\/00003495-200059010-00002"},{"key":"e_1_3_2_6_2","doi-asserted-by":"publisher","DOI":"10.1007\/PL00012242"},{"key":"e_1_3_2_7_2","first-page":"477","article-title":"Epidemiolog\u0131\u0301a del micetoma en M\u00e9xico: estudio de 2105 casos.","volume":"128","author":"L\u00f3pez-Mart\u0131\u0301nez R.","year":"1992","unstructured":"L\u00f3pez-Mart\u0131\u0301nez R. 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Document M7\u2013A4.\n          1997\n          National Committee for Clinical Laboratory Standards\n          Wayne Pa"},{"key":"e_1_3_2_9_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.43.8.2059"},{"key":"e_1_3_2_10_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.42.3.721"},{"key":"e_1_3_2_11_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.41.10.2132"},{"key":"e_1_3_2_12_2","first-page":"183","article-title":"Experimental mycetoma by Nocardia brasiliensis in rats.","volume":"8","author":"Vera-Cabrera L.","year":"1998","unstructured":"Vera-Cabrera L. Rodr\u0131\u0301guez-Quintanilla M. A. Boiron P. Salinas-Carmona M. C. Welsh O. Experimental mycetoma by Nocardia brasiliensis in rats. J. Mycol. Med. 8 1998 183 187","journal-title":"J. Mycol. 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Lippincott Company\n          Philadelphia Pa"},{"key":"e_1_3_2_17_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.40.4.839"}],"container-title":["Antimicrobial Agents and Chemotherapy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/AAC.45.12.3629-3630.2001","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/AAC.45.12.3629-3630.2001","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,2,21]],"date-time":"2022-02-21T16:57:57Z","timestamp":1645462677000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.asm.org\/doi\/10.1128\/AAC.45.12.3629-3630.2001"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2001,12]]},"references-count":16,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2001,12]]}},"alternative-id":["10.1128\/AAC.45.12.3629-3630.2001"],"URL":"https:\/\/doi.org\/10.1128\/aac.45.12.3629-3630.2001","relation":{},"ISSN":["0066-4804","1098-6596"],"issn-type":[{"value":"0066-4804","type":"print"},{"value":"1098-6596","type":"electronic"}],"subject":[],"published":{"date-parts":[[2001,12]]},"assertion":[{"value":"2000-11-06","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2001-09-14","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2001-12-01","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}