{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,14]],"date-time":"2026-09-14T02:22:34Z","timestamp":1789352554793,"version":"build-2803163510"},"reference-count":18,"publisher":"American Society for Microbiology","issue":"12","license":[{"start":{"date-parts":[[2001,12,1]],"date-time":"2001-12-01T00:00:00Z","timestamp":1007164800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["Antimicrob Agents Chemother"],"published-print":{"date-parts":[[2001,12]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n          <jats:p>\n            The effectiveness of newer macrolides in acute Q fever for 113 patients was recorded. The mean times to defervescence were 2.9 days for doxycycline and 3.3, 3.9, 3.9, and 6.4 days for clarithromycin, roxithromycin, erythromycin, and \u03b2-lactams, respectively (\n            <jats:italic>P<\/jats:italic>\n            &lt; 0.01 for macrolides versus \u03b2-lactams). We conclude that macrolides may be an adequate empirical antibiotic therapy for acute Q fever.\n          <\/jats:p>","DOI":"10.1128\/aac.45.12.3644-3646.2001","type":"journal-article","created":{"date-parts":[[2002,7,27]],"date-time":"2002-07-27T10:06:42Z","timestamp":1027764402000},"page":"3644-3646","update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":47,"title":["Newer Macrolides as Empiric Treatment for Acute Q Fever Infection"],"prefix":"10.1128","volume":"45","author":[{"given":"Achilleas","family":"Gikas","sequence":"first","affiliation":[{"name":"<!--label omitted: 1-->Zoonoses and Clinical Bacteriology, Parasitology, Geographical Medicine, and Department of Internal Medicine, University Hospital of Heraklion, Heraklion, Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Diamantis P.","family":"Kofteridis","sequence":"additional","affiliation":[{"name":"<!--label omitted: 1-->Zoonoses and Clinical Bacteriology, Parasitology, Geographical Medicine, and Department of Internal Medicine, University Hospital of Heraklion, Heraklion, Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andreas","family":"Manios","sequence":"additional","affiliation":[{"name":"<!--label omitted: 1-->Zoonoses and Clinical Bacteriology, Parasitology, Geographical Medicine, and Department of Internal Medicine, University Hospital of Heraklion, Heraklion, Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John","family":"Pediaditis","sequence":"additional","affiliation":[{"name":"<!--label omitted: 1-->Zoonoses and Clinical Bacteriology, Parasitology, Geographical Medicine, and Department of Internal Medicine, University Hospital of Heraklion, Heraklion, Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yiannis","family":"Tselentis","sequence":"additional","affiliation":[{"name":"<!--label omitted: 1-->Zoonoses and Clinical Bacteriology, Parasitology, Geographical Medicine, and Department of Internal Medicine, University Hospital of Heraklion, Heraklion, Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"235","reference":[{"key":"e_1_3_1_2_2","doi-asserted-by":"publisher","DOI":"10.1378\/chest.114.3.808"},{"key":"e_1_3_1_3_2","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.2.6185.305"},{"key":"e_1_3_1_4_2","first-page":"814","article-title":"Aspects clinics observes lors d'une epidemie de 415 cas de fievre Q.","volume":"115","author":"Dupuis G.","year":"1985","unstructured":"Dupuis G. Peter O. Pedroni D. Petite J. Aspects clinics observes lors d'une epidemie de 415 cas de fievre Q. Schweiz. Med. Wochenschr. 115 1985 814 818","journal-title":"Schweiz. Med. Wochenschr."},{"key":"e_1_3_1_5_2","doi-asserted-by":"publisher","DOI":"10.1136\/thx.37.11.867"},{"key":"e_1_3_1_6_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.42.10.2747"},{"key":"e_1_3_1_7_2","doi-asserted-by":"publisher","DOI":"10.1093\/jac\/38.4.727"},{"key":"e_1_3_1_8_2","first-page":"295","article-title":"Acute Q fever as a cause of acute febrile illness of unknown origin in Taiwan: report of seven cases.","volume":"96","author":"Ko W. C.","year":"1997","unstructured":"Ko W. C. Liu J. W. Chuang Y. C. Acute Q fever as a cause of acute febrile illness of unknown origin in Taiwan: report of seven cases. J. Formos. Med. Assoc. 96 1997 295 297","journal-title":"J. Formos. Med. Assoc."},{"key":"e_1_3_1_9_2","unstructured":"Marrie\n              T. J. Coxiella burnetii Principles and practice of infectious disease\n          3rd ed.\n              Mandell\n              G. L.\n              Douglas\n              R. G. J.\n              Bennett\n              J. E.\n          1990\n          1472\n          1476\n          Churchill Livingstone\n          New York N.Y"},{"key":"e_1_3_1_10_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.37.12.2633"},{"key":"e_1_3_1_11_2","doi-asserted-by":"publisher","DOI":"10.1093\/clinids\/7.5.700"},{"key":"e_1_3_1_12_2","doi-asserted-by":"publisher","DOI":"10.1093\/jac\/28.3.455"},{"key":"e_1_3_1_13_2","doi-asserted-by":"publisher","DOI":"10.1097\/00005792-200003000-00005"},{"key":"e_1_3_1_14_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.34.8.1512"},{"key":"e_1_3_1_15_2","doi-asserted-by":"publisher","DOI":"10.1017\/S095026880004797X"},{"key":"e_1_3_1_16_2","doi-asserted-by":"publisher","DOI":"10.5694\/j.1326-5377.1982.tb124169.x"},{"key":"e_1_3_1_17_2","doi-asserted-by":"publisher","DOI":"10.1093\/clinids\/20.5.1311"},{"key":"e_1_3_1_18_2","first-page":"213","article-title":"Antibiotic susceptibility of Coxiella burnetii","volume":"1","author":"Yeaman M. R.","year":"1990","unstructured":"Yeaman M. R. Baca O. G. Antibiotic susceptibility of Coxiella burnetii Q fever. The disease Marrie T. J. 1 1990 213 223 CRC Press Boca Raton, Fla","journal-title":"Q fever. The disease"},{"key":"e_1_3_1_19_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.31.7.1079"}],"container-title":["Antimicrobial Agents and Chemotherapy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/AAC.45.12.3644-3646.2001","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/AAC.45.12.3644-3646.2001","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,2,21]],"date-time":"2022-02-21T16:58:18Z","timestamp":1645462698000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.asm.org\/doi\/10.1128\/AAC.45.12.3644-3646.2001"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2001,12]]},"references-count":18,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2001,12]]}},"alternative-id":["10.1128\/AAC.45.12.3644-3646.2001"],"URL":"https:\/\/doi.org\/10.1128\/aac.45.12.3644-3646.2001","relation":{},"ISSN":["0066-4804","1098-6596"],"issn-type":[{"value":"0066-4804","type":"print"},{"value":"1098-6596","type":"electronic"}],"subject":[],"published":{"date-parts":[[2001,12]]},"assertion":[{"value":"2000-11-03","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2001-09-19","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2001-12-01","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}