{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,27]],"date-time":"2025-10-27T15:47:37Z","timestamp":1761580057956},"reference-count":11,"publisher":"American Society for Microbiology","issue":"6","license":[{"start":{"date-parts":[[2001,6,1]],"date-time":"2001-06-01T00:00:00Z","timestamp":991353600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["Antimicrob Agents Chemother"],"published-print":{"date-parts":[[2001,6]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n          <jats:p>\n            A total of 105 isolates of\n            <jats:italic>Mycoplasma pneumoniae<\/jats:italic>\n            were evaluated for susceptibility to moxifloxacin, sparfloxacin, levofloxacin, and ciprofloxacin. Moxifloxacin, a newly synthesized compound, showed the greatest activity. The MICs and MBCs at which 50 and 90% of isolates were affected were 0.15 (MIC\n            <jats:sub>50<\/jats:sub>\n            and MBC\n            <jats:sub>50<\/jats:sub>\n            ) and 0.3 \u03bcg\/ml (MIC\n            <jats:sub>90<\/jats:sub>\n            and MBC\n            <jats:sub>90<\/jats:sub>\n            ) respectively. The results indicate that moxifloxacin might be promising an antimycoplasmal agent.\n          <\/jats:p>","DOI":"10.1128\/aac.45.6.1908-1910.2001","type":"journal-article","created":{"date-parts":[[2002,7,27]],"date-time":"2002-07-27T10:06:42Z","timestamp":1027764402000},"page":"1908-1910","update-policy":"http:\/\/dx.doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":13,"title":["In Vitro Activities of Moxifloxacin and Other Fluoroquinolones against\n            <i>Mycoplasma pneumoniae<\/i>"],"prefix":"10.1128","volume":"45","author":[{"given":"Kumiko","family":"Hamamoto","sequence":"first","affiliation":[{"name":"<!--label omitted: 1-->Department of Bacteriology, Kurume University School of Medicine, 67 Asahimachi, Kurume, Fukuoka, 830-0011, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takashi","family":"Shimizu","sequence":"additional","affiliation":[{"name":"<!--label omitted: 1-->Department of Bacteriology, Kurume University School of Medicine, 67 Asahimachi, Kurume, Fukuoka, 830-0011, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Naoyuki","family":"Fujimoto","sequence":"additional","affiliation":[{"name":"<!--label omitted: 1-->Department of Bacteriology, Kurume University School of Medicine, 67 Asahimachi, Kurume, Fukuoka, 830-0011, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ye","family":"Zhang","sequence":"additional","affiliation":[{"name":"<!--label omitted: 1-->Department of Bacteriology, Kurume University School of Medicine, 67 Asahimachi, Kurume, Fukuoka, 830-0011, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sumio","family":"Arai","sequence":"additional","affiliation":[{"name":"<!--label omitted: 1-->Department of Bacteriology, Kurume University School of Medicine, 67 Asahimachi, Kurume, Fukuoka, 830-0011, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"235","reference":[{"key":"e_1_3_1_2_2","doi-asserted-by":"crossref","first-page":"1594","DOI":"10.1128\/AAC.41.7.1594","article-title":"In vitro activity of BAY 12-8039, a novel 8-methoxyquinolone, compared to activities of six fluoroquinolones against Streptococcus pneumoniae, Haemophilus influenzae, and Moraxella catarrhalis.","volume":"41","author":"Angela B. B.","year":"1997","unstructured":"Angela B. B. Kari C. K. Gary V. D. In vitro activity of BAY 12-8039, a novel 8-methoxyquinolone, compared to activities of six fluoroquinolones against Streptococcus pneumoniae, Haemophilus influenzae, and Moraxella catarrhalis. Antimicrob. Agents Chemother. 41 1997 1594 1597","journal-title":"Antimicrob. Agents Chemother."},{"key":"e_1_3_1_3_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.37.2.287"},{"key":"e_1_3_1_4_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.41.6.1377"},{"key":"e_1_3_1_5_2","doi-asserted-by":"crossref","first-page":"433","DOI":"10.1016\/0732-8893(89)90115-6","article-title":"Comparative susceptibility of Mycoplasma pneumoniae to erythromycin, ciprofloxacin, and lomefloxacin.","volume":"12","author":"Cassell G. H.","year":"1989","unstructured":"Cassell G. H. Waites K. B. Pate M. S. Canupp K. C. Duffy L. B. Comparative susceptibility of Mycoplasma pneumoniae to erythromycin, ciprofloxacin, and lomefloxacin. Diagn. Microbiol. Infect. Dis. 12 1989 433 435","journal-title":"Diagn. Microbiol. Infect. Dis."},{"key":"e_1_3_1_6_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.37.9.1826"},{"key":"e_1_3_1_7_2","unstructured":"Grayston\n              J. T.\n              Foy\n              H. M.\n              Kenny\n              G. E.\n          The epidemiology of mycoplasma infections of the human respiratory tract\n          The mycoplasmatales and the L-phase of bacteria.\n              Hayflick\n              L.\n          1969\n          651\n          682\n          Appelton-Century-Crofts\n          Amsterdam The Netherlands"},{"key":"e_1_3_1_8_2","doi-asserted-by":"crossref","first-page":"438","DOI":"10.1016\/S0022-3476(70)80485-1","article-title":"Registance of Mycoplasma pneumoniae to erythromycin and other antibiotics.","volume":"76","author":"Niitu Y.","year":"1970","unstructured":"Niitu Y. Hasegawa S. Suetake T. Kubota H. Komatsu S. Horikawa M. Registance of Mycoplasma pneumoniae to erythromycin and other antibiotics. J. Pediatr. 76 1970 438 443","journal-title":"J. Pediatr."},{"key":"e_1_3_1_9_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.18.5.699"},{"key":"e_1_3_1_10_2","first-page":"689","article-title":"The synthesis and biological properties of 6-fluoroquinolone-carboxylic acids.","volume":"105","author":"Petersen U.","year":"1996","unstructured":"Petersen U. Bartel S. Bremm K.-D. Himmler T. Krebs A. Schenke T. The synthesis and biological properties of 6-fluoroquinolone-carboxylic acids. Bull. Soc. Chim. Belg. 105 1996 689 699","journal-title":"Bull. Soc. Chim. 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