{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,11]],"date-time":"2025-07-11T10:44:43Z","timestamp":1752230683111},"reference-count":14,"publisher":"American Society for Microbiology","issue":"1","license":[{"start":{"date-parts":[[2002,1,1]],"date-time":"2002-01-01T00:00:00Z","timestamp":1009843200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["Antimicrob Agents Chemother"],"published-print":{"date-parts":[[2002,1]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n          <jats:p>\n            2-(2\u2033-Dichloroacetamidobenzyl)-3-(3\u2032-indolylquinoline), designated indolylquinoline derivative A, reduced the splenic and the liver parasite burdens by &gt;93.0% in\n            <jats:italic>Leishmania donovani<\/jats:italic>\n            -infected hamsters, whereas sodium antimony gluconate (SAG) reduced the burdens approximately 80.0%. Complete clearance of parasitemia from the livers and spleens was noticed when infected animals received indolylquinoline derivative A plus SAG, suggesting that indolylquinoline derivative A has potential as a new agent for sole or conjunctive therapy for leishmaniasis.\n          <\/jats:p>","DOI":"10.1128\/aac.46.1.259-261.2002","type":"journal-article","created":{"date-parts":[[2002,7,27]],"date-time":"2002-07-27T09:56:57Z","timestamp":1027763817000},"page":"259-261","update-policy":"http:\/\/dx.doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":14,"title":["Combination Therapy with Indolylquinoline Derivative and Sodium Antimony Gluconate Cures Established Visceral Leishmaniasis in Hamsters"],"prefix":"10.1128","volume":"46","author":[{"given":"Chiranjib","family":"Pal","sequence":"first","affiliation":[{"name":"Immunology Division"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mousumi","family":"Raha","sequence":"additional","affiliation":[{"name":"Steroid and Terpenoid Chemistry Division, Indian Institute of Chemical Biology, Jadavpur, Kolkata-700 032"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anirban","family":"Basu","sequence":"additional","affiliation":[{"name":"Immunology Division"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Keshab Chandra","family":"Roy","sequence":"additional","affiliation":[{"name":"Immunology Division"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anasuya","family":"Gupta","sequence":"additional","affiliation":[{"name":"Department of Zoology, Calcutta University, Kolkata-700 019, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Monidipa","family":"Ghosh","sequence":"additional","affiliation":[{"name":"Immunology Division"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Niranjan Prasad","family":"Sahu","sequence":"additional","affiliation":[{"name":"Steroid and Terpenoid Chemistry Division, Indian Institute of Chemical Biology, Jadavpur, Kolkata-700 032"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sukdeb","family":"Banerjee","sequence":"additional","affiliation":[{"name":"Steroid and Terpenoid Chemistry Division, Indian Institute of Chemical Biology, Jadavpur, Kolkata-700 032"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nirup Bikash","family":"Mandal","sequence":"additional","affiliation":[{"name":"Steroid and Terpenoid Chemistry Division, Indian Institute of Chemical Biology, Jadavpur, Kolkata-700 032"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Santu","family":"Bandyopadhyay","sequence":"additional","affiliation":[{"name":"Immunology Division"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"235","reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"crossref","first-page":"1103","DOI":"10.1089\/107999099313037","volume":"19","year":"1999","unstructured":"Bhakuni, V., S. Kulkarni, V. Ali, U. K. Singh, H. B. Levy, and R. K. Maheshwari. 1999. Immunotherapy for Leishmania donovani infection in golden hamsters: combinatorial action of poly ICLC plus l-arginine and sodium stibogluconate (stibanate). J. Interferon Cytokine Res.19:1103\u20131106.","journal-title":"J. Interferon Cytokine Res."},{"key":"e_1_3_2_3_2","doi-asserted-by":"crossref","first-page":"359","DOI":"10.1093\/jac\/43.3.359","volume":"43","year":"1999","unstructured":"Chakrabarti, G., A. Basu, P. P. Manna, S. B. Mahato, N. B. Mandal, and S. Bandyopadhyay. 1999. Indolylquinoline derivatives are cytotoxic to Leishmaniadonovani promastigotes and amastigotes in vitro and are effective in treating murine visceral leishmaniasis. J. Antimicrob. Chemother.43:359\u2013366.","journal-title":"J. Antimicrob. 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