{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T03:49:09Z","timestamp":1777348149070,"version":"3.51.4"},"reference-count":14,"publisher":"American Society for Microbiology","issue":"3","license":[{"start":{"date-parts":[[2002,3,1]],"date-time":"2002-03-01T00:00:00Z","timestamp":1014940800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["Antimicrob Agents Chemother"],"published-print":{"date-parts":[[2002,3]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n          <jats:p>\n            As part of the SENTRY antimicrobial surveillance program, we examined the prevalence rates, types, and antibiograms of oxacillin-resistant\n            <jats:italic>Staphylococcus aureus<\/jats:italic>\n            from hospitalized patients from 17 institutions in eight countries in Asia-Pacific and South Africa (APAC). From April 1998 to December 1999, a total of 1,711 isolates of\n            <jats:italic>S. aureus<\/jats:italic>\n            (814 from blood, 392 from the respiratory tract, 467 from skin and skin structures, and 38 from urine) were collected from hospitalized patients within the APAC region. Multidrug-resistant oxacillin-resistant\n            <jats:italic>S. aureus<\/jats:italic>\n            (MORSA) isolates, defined as strains with three or more resistances to drug classes other than \u03b2-lactams, were the most common type of oxacillin-resistant\n            <jats:italic>S. aureus<\/jats:italic>\n            (ORSA). They were the most frequently identified pathogen in wound infections and were common in bloodstream and lower respiratory tract infections. In all contributing institutions combined, more than 45% (range, 4 to 74%) of\n            <jats:italic>S. aureus<\/jats:italic>\n            isolates were oxacillin resistant, and in six institutions, this rate exceeded 60%. MORSA accounted for 91.2% of all oxacillin-resistant isolates. Distinct resistance patterns predominated at various sites within the APAC region, suggesting the local evolution of resistant clones. Non-multidrug-resistant strains were frequent in one part of Australia. No vancomycin-intermediate strains were detected, and no strains were resistant to linezolid or quinupristin-dalfopristin. MORSA strains are a very common cause of infection in hospitalized patients in the APAC region.\n          <\/jats:p>","DOI":"10.1128\/aac.46.3.880-882.2002","type":"journal-article","created":{"date-parts":[[2002,7,27]],"date-time":"2002-07-27T05:58:35Z","timestamp":1027749515000},"page":"879-881","update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":76,"title":["High Prevalence of Oxacillin-Resistant\n            <i>Staphylococcus aureus<\/i>\n            Isolates from Hospitalized Patients in Asia-Pacific and South Africa: Results from SENTRY Antimicrobial Surveillance Program, 1998-1999"],"prefix":"10.1128","volume":"46","author":[{"given":"Jan M.","family":"Bell","sequence":"first","affiliation":[{"name":"Department of Microbiology and Infectious Diseases, Women's and Children's Hospital, North Adelaide SA 5006, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"John D.","family":"Turnidge","sequence":"additional","affiliation":[{"name":"Department of Microbiology and Infectious Diseases, Women's and Children's Hospital, North Adelaide SA 5006, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"235","reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.1086\/501641"},{"key":"e_1_3_3_3_2","doi-asserted-by":"publisher","DOI":"10.1093\/clinids\/24.Supplement_1.S74"},{"key":"e_1_3_3_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0732-8893(01)00242-5"},{"key":"e_1_3_3_5_2","doi-asserted-by":"publisher","DOI":"10.1086\/320184"},{"key":"e_1_3_3_6_2","first-page":"646","volume":"15","year":"1994","unstructured":"Embil, J., K. Ramotar, L. Romance et al. 1994. Methicillin-resistant Staphylococcus aureus in tertiary care institutions on the Canadian prairies 1990-1992. Infect. Control Hosp. Epidemiol.15:646-651.","journal-title":"Infect. Control Hosp. Epidemiol."},{"key":"e_1_3_3_7_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.279.8.593"},{"key":"e_1_3_3_8_2","doi-asserted-by":"publisher","DOI":"10.1093\/jac\/40.1.135"},{"key":"e_1_3_3_9_2","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.1.5219.124-a"},{"key":"e_1_3_3_10_2","first-page":"411.","volume":"109","year":"1996","unstructured":"Mitchell, J. M., D. MacCulloch, and A. J. Morris. 1996. MRSA in the community. N. Z. Med. J.109:411.","journal-title":"N. Z. Med. J."},{"key":"e_1_3_3_11_2","unstructured":"National Committee for Clinical Laboratory Standards. 2000. Methods for dilution antimicrobial susceptibility tests for bacteria that grow aerobically 5th ed. Approved standard M7-A5. National Committee for Clinical Laboratory Standards Wayne Pa."},{"key":"e_1_3_3_12_2","unstructured":"National Committee for Clinical Laboratory Standards. 2000. Performance standards for antimicrobial susceptibility testing. Tenth informational supplement. M100-S10. National Committee for Clinical Laboratory Standards Wayne Pa."},{"key":"e_1_3_3_13_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.42.7.1762"},{"key":"e_1_3_3_14_2","doi-asserted-by":"publisher","DOI":"10.1089\/mdr.2000.6.223"},{"key":"e_1_3_3_15_2","doi-asserted-by":"publisher","DOI":"10.5694\/j.1326-5377.1996.tb101350.x"}],"container-title":["Antimicrobial Agents and Chemotherapy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/AAC.46.3.880-882.2002","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/AAC.46.3.880-882.2002","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,2,21]],"date-time":"2022-02-21T12:41:25Z","timestamp":1645447285000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.asm.org\/doi\/10.1128\/AAC.46.3.880-882.2002"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2002,3]]},"references-count":14,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2002,3]]}},"alternative-id":["10.1128\/AAC.46.3.880-882.2002"],"URL":"https:\/\/doi.org\/10.1128\/aac.46.3.880-882.2002","relation":{},"ISSN":["0066-4804","1098-6596"],"issn-type":[{"value":"0066-4804","type":"print"},{"value":"1098-6596","type":"electronic"}],"subject":[],"published":{"date-parts":[[2002,3]]},"assertion":[{"value":"2001-01-12","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2001-11-23","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2002-03-01","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}