{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,22]],"date-time":"2026-07-22T03:47:08Z","timestamp":1784692028018,"version":"3.55.0"},"reference-count":14,"publisher":"American Society for Microbiology","issue":"10","license":[{"start":{"date-parts":[[2003,10,1]],"date-time":"2003-10-01T00:00:00Z","timestamp":1064966400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["Antimicrob Agents Chemother"],"published-print":{"date-parts":[[2003,10]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n          <jats:p>\n            The efficacies of liposomal amphotericin B (LAmB) and amphotericin B deoxycholate (AmB) were compared in a diabetic murine model of hematogenously disseminated\n            <jats:italic>Rhizopus oryzae<\/jats:italic>\n            infection. At 7.5 mg\/kg of body weight twice a day (b.i.d.), LAmB significantly improved overall survival compared to the rates of survival in both untreated control mice (\n            <jats:italic>P<\/jats:italic>\n            = 0.001) and mice treated with 0.5 mg of AmB per kg b.i.d. (\n            <jats:italic>P<\/jats:italic>\n            = 0.047). These data indicate that high-dose LAmB is more effective than AmB in treating murine disseminated zygomycosis.\n          <\/jats:p>","DOI":"10.1128\/aac.47.10.3343-3344.2003","type":"journal-article","created":{"date-parts":[[2003,9,23]],"date-time":"2003-09-23T22:25:36Z","timestamp":1064355936000},"page":"3343-3344","update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":84,"title":["Liposomal Amphotericin B, and Not Amphotericin B Deoxycholate, Improves Survival of Diabetic Mice Infected with\n            <i>Rhizopus oryzae<\/i>"],"prefix":"10.1128","volume":"47","author":[{"given":"Ashraf S.","family":"Ibrahim","sequence":"first","affiliation":[{"name":"Harbor-UCLA Research and Education Institute, Torrance, California 90502"},{"name":"UCLA School of Medicine, Los Angeles, California 90024"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Valentina","family":"Avanessian","sequence":"additional","affiliation":[{"name":"Harbor-UCLA Research and Education Institute, Torrance, California 90502"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brad","family":"Spellberg","sequence":"additional","affiliation":[{"name":"Harbor-UCLA Research and Education Institute, Torrance, California 90502"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"suffix":"Jr.","given":"John E.","family":"Edwards","sequence":"additional","affiliation":[{"name":"Harbor-UCLA Research and Education Institute, Torrance, California 90502"},{"name":"UCLA School of Medicine, Los Angeles, California 90024"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"235","reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1093\/jac\/49.suppl_1.21"},{"key":"e_1_3_2_3_2","first-page":"1","volume":"28","year":"1994","unstructured":"Boelaert, J. 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