{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,9,13]],"date-time":"2023-09-13T16:19:46Z","timestamp":1694621986360},"reference-count":7,"publisher":"American Society for Microbiology","issue":"1","license":[{"start":{"date-parts":[[2004,1,1]],"date-time":"2004-01-01T00:00:00Z","timestamp":1072915200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["Antimicrob Agents Chemother"],"published-print":{"date-parts":[[2004,1]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n          <jats:p>\n            Testing of susceptibility to penicillin G by E-test and sequencing of an internal fragment of the\n            <jats:italic>penA<\/jats:italic>\n            gene were done for 43 meningococcal strains. Those strains for which the MIC was \u22650.094 \u03bcg\/ml showed mosaic alleles, so 0.094 \u03bcg\/ml is suggested as the penicillin G intermediate breakpoint when E-test is used.\n          <\/jats:p>","DOI":"10.1128\/aac.48.1.358-359.2004","type":"journal-article","created":{"date-parts":[[2003,12,24]],"date-time":"2003-12-24T02:03:22Z","timestamp":1072231402000},"page":"358-359","update-policy":"http:\/\/dx.doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":12,"title":["Sequencing of\n            <i>Neisseria meningitidis penA<\/i>\n            Gene: the Key to Success in Defining Penicillin G Breakpoints"],"prefix":"10.1128","volume":"48","author":[{"given":"Luisa","family":"Arreaza","sequence":"first","affiliation":[{"name":"Reference Laboratory for Meningococci, National Center of Microbiology, Institute of Health Carlos III, Madrid, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Celia","family":"Salcedo","sequence":"additional","affiliation":[{"name":"Reference Laboratory for Meningococci, National Center of Microbiology, Institute of Health Carlos III, Madrid, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bele\u0301n","family":"Alcala\u0301","sequence":"additional","affiliation":[{"name":"Reference Laboratory for Meningococci, National Center of Microbiology, Institute of Health Carlos III, Madrid, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mari\u0301a Jose\u0301","family":"Uri\u0301a","sequence":"additional","affiliation":[{"name":"Reference Laboratory for Meningococci, National Center of Microbiology, Institute of Health Carlos III, Madrid, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Raquel","family":"Abad","sequence":"additional","affiliation":[{"name":"Reference Laboratory for Meningococci, National Center of Microbiology, Institute of Health Carlos III, Madrid, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Roci\u0301o","family":"Enri\u0301quez","sequence":"additional","affiliation":[{"name":"Reference Laboratory for Meningococci, National Center of Microbiology, Institute of Health Carlos III, Madrid, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Julio A.","family":"Va\u0301zquez","sequence":"additional","affiliation":[{"name":"Reference Laboratory for Meningococci, National Center of Microbiology, Institute of Health Carlos III, Madrid, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"235","reference":[{"key":"e_1_3_2_2_2","first-page":"107","volume":"67","year":"2001","unstructured":"Arreaza, L., and J. 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