{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,2]],"date-time":"2025-12-02T15:13:29Z","timestamp":1764688409642},"reference-count":14,"publisher":"American Society for Microbiology","issue":"10","license":[{"start":{"date-parts":[[2004,10,1]],"date-time":"2004-10-01T00:00:00Z","timestamp":1096588800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["Antimicrob Agents Chemother"],"published-print":{"date-parts":[[2004,10]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n          <jats:p>\n            A sequential therapy of caspofungin (CAS) and fluconazole (FLC) administration for treatment of\n            <jats:italic>Candida albicans<\/jats:italic>\n            infection was investigated. Treatment with CAS followed by FLC was as effective as CAS treatment given alone for the same duration. Our data suggest that switching from CAS to FLC is a potentially explorable therapeutic option for treatment of systemic candidiasis.\n          <\/jats:p>","DOI":"10.1128\/aac.48.10.4056-4058.2004","type":"journal-article","created":{"date-parts":[[2004,9,23]],"date-time":"2004-09-23T19:02:50Z","timestamp":1095966170000},"page":"4056-4058","update-policy":"http:\/\/dx.doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":7,"title":["Sequential Therapy with Caspofungin and Fluconazole for\n            <i>Candida albicans<\/i>\n            Infection"],"prefix":"10.1128","volume":"48","author":[{"given":"Francesco","family":"Barchiesi","sequence":"first","affiliation":[{"name":"Istituto di Malattie Infettive e Medicina Pubblica"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elisabetta","family":"Spreghini","sequence":"additional","affiliation":[{"name":"Istituto di Malattie Infettive e Medicina Pubblica"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Isabella","family":"Baldassarri","sequence":"additional","affiliation":[{"name":"Istituto di Malattie Infettive e Medicina Pubblica"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anna","family":"Marigliano","sequence":"additional","affiliation":[{"name":"Istituto di Malattie Infettive e Medicina Pubblica"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daniela","family":"Arzeni","sequence":"additional","affiliation":[{"name":"Istituto di Malattie Infettive e Medicina Pubblica"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daniele","family":"Giannini","sequence":"additional","affiliation":[{"name":"Centro di Gestione Presidenza Medicina e Chirurgia, Universita\u0300 Politecnica delle Marche, Ancona, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Giorgio","family":"Scalise","sequence":"additional","affiliation":[{"name":"Istituto di Malattie Infettive e Medicina Pubblica"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"235","reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.46.1.245-247.2002"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.40.6.2228-2230.2002"},{"key":"e_1_3_2_4_2","first-page":"302","volume":"18","year":"1999","unstructured":"Barchiesi, F., A. 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