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In two studies, all formulations prolonged survival, with the results for AmBisome nearly equivalent to those for Fungizone; Amphocil and Abelcet were less effective or equivalent depending on the severity of infection. No survivors were cured in both kidneys and brain, but each formulation showed efficacy, especially in the kidneys. Although higher doses could be given, no lipid-based formulation showed consistent superiority over Fungizone or over each other.<\/jats:p>","DOI":"10.1128\/aac.48.3.1047-1050.2004","type":"journal-article","created":{"date-parts":[[2004,2,24]],"date-time":"2004-02-24T17:53:08Z","timestamp":1077645188000},"page":"1047-1050","update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":72,"title":["Comparative Efficacies of Four Amphotericin B Formulations\u2014Fungizone, Amphotec (Amphocil), AmBisome, and Abelcet\u2014against Systemic Murine Aspergillosis"],"prefix":"10.1128","volume":"48","author":[{"given":"Karl V.","family":"Clemons","sequence":"first","affiliation":[{"name":"California Institute for Medical Research and Department of Medicine, Division of Infectious Diseases, Santa Clara Valley Medical Center, San Jose, California 95128"},{"name":"Department of Medicine, Division of Infectious Diseases and Geographic Medicine, Stanford University, Stanford, California 94305"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David A.","family":"Stevens","sequence":"additional","affiliation":[{"name":"California Institute for Medical Research and Department of Medicine, Division of Infectious Diseases, Santa Clara Valley Medical Center, San Jose, California 95128"},{"name":"Department of Medicine, Division of Infectious Diseases and Geographic Medicine, Stanford University, Stanford, California 94305"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"235","reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1093\/jac\/49.suppl_1.21"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1093\/jac\/34.6.1001"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.38.3.518"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.35.4.615"},{"key":"e_1_3_2_6_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.38.3.460"},{"key":"e_1_3_2_7_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.45.2.612-615.2001"},{"key":"e_1_3_2_8_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.35.10.2144"},{"key":"e_1_3_2_9_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.35.9.1829"},{"key":"e_1_3_2_10_2","doi-asserted-by":"crossref","first-page":"353","DOI":"10.1093\/jac\/30.3.353","volume":"30","year":"1992","unstructured":"Clemons, K. 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