{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T19:13:14Z","timestamp":1790709194592,"version":"4.1.0"},"reference-count":33,"publisher":"American Society for Microbiology","issue":"3","license":[{"start":{"date-parts":[[2004,3,1]],"date-time":"2004-03-01T00:00:00Z","timestamp":1078099200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["Antimicrob Agents Chemother"],"published-print":{"date-parts":[[2004,3]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n          <jats:p>\n            Fifty-eight multidrug-resistant\n            <jats:italic>Salmonella enterica<\/jats:italic>\n            strains of 20 serotypes, isolated from animal sources in Italy, were analyzed for\n            <jats:italic>tet<\/jats:italic>\n            (A) and\n            <jats:italic>strA<\/jats:italic>\n            -\n            <jats:italic>strB<\/jats:italic>\n            , conferring tetracycline and streptomycin resistance, respectively. The\n            <jats:italic>strA<\/jats:italic>\n            and\n            <jats:italic>strB<\/jats:italic>\n            genes were highly prevalent in\n            <jats:italic>Salmonella<\/jats:italic>\n            strains of our collection, being detected in 84% of the streptomycin-resistant strains. In many strains, the\n            <jats:italic>strA<\/jats:italic>\n            and\n            <jats:italic>strB<\/jats:italic>\n            genes were linked to a particular Tn\n            <jats:italic>5393-<\/jats:italic>\n            derivative transposon characterized by the presence of the insertion sequence IS\n            <jats:italic>1133<\/jats:italic>\n            , previously identified only in the plant pathogen\n            <jats:italic>Erwinia amylovora.<\/jats:italic>\n            Sixty-eight percent of the tetracycline-resistant strains were\n            <jats:italic>tet<\/jats:italic>\n            (A) positive, indicating that this gene is widely diffused in\n            <jats:italic>Salmonella<\/jats:italic>\n            strains circulating in animals in Italy. Most of the\n            <jats:italic>tet<\/jats:italic>\n            (A) genes were localized within a deleted Tn\n            <jats:italic>1721<\/jats:italic>\n            transposon variant. Two prevalent repN and repI1 resistance plasmids were identified in\n            <jats:italic>Salmonella<\/jats:italic>\n            isolates of our collection.\n          <\/jats:p>","DOI":"10.1128\/aac.48.3.903-908.2004","type":"journal-article","created":{"date-parts":[[2004,2,24]],"date-time":"2004-02-24T17:53:08Z","timestamp":1077645188000},"page":"903-908","update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":109,"title":["Tetracycline and Streptomycin Resistance Genes, Transposons, and Plasmids in\n            <i>Salmonella enterica<\/i>\n            Isolates from Animals in Italy"],"prefix":"10.1128","volume":"48","author":[{"given":"Cristina","family":"Pezzella","sequence":"first","affiliation":[{"name":"Laboratory of Bacteriology and Medical Mycology, Istituto Superiore di Sanita\u0300, Rome"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antonia","family":"Ricci","sequence":"additional","affiliation":[{"name":"Istituto Zooprofilattico Sperimentale delle Venezie, Padua"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elisabetta","family":"DiGiannatale","sequence":"additional","affiliation":[{"name":"Istituto Zooprofilattico Sperimentale di Abruzzo e Molise, Teramo, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ida","family":"Luzzi","sequence":"additional","affiliation":[{"name":"Laboratory of Bacteriology and Medical Mycology, Istituto Superiore di Sanita\u0300, Rome"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alessandra","family":"Carattoli","sequence":"additional","affiliation":[{"name":"Laboratory of Bacteriology and Medical Mycology, Istituto Superiore di Sanita\u0300, Rome"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"235","reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/0378-1119(92)90597-I"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1017\/S0022172400056187"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.1128\/JB.183.19.5725-5732.2001"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.46.9.2821-2828.2002"},{"key":"e_1_3_2_6_2","doi-asserted-by":"publisher","DOI":"10.1128\/MMBR.65.2.232-260.2001"},{"key":"e_1_3_2_7_2","doi-asserted-by":"publisher","DOI":"10.1051\/vetres:2001126"},{"key":"e_1_3_2_8_2","doi-asserted-by":"publisher","DOI":"10.1128\/mr.52.3.375-395.1988"},{"key":"e_1_3_2_9_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.42.5.1288"},{"key":"e_1_3_2_10_2","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1111\/j.1574-6968.1999.tb13648.x","volume":"176","year":"1999","unstructured":"Frech, G., and S. 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