{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,2]],"date-time":"2025-11-02T10:15:27Z","timestamp":1762078527024},"reference-count":8,"publisher":"American Society for Microbiology","issue":"6","license":[{"start":{"date-parts":[[2004,6,1]],"date-time":"2004-06-01T00:00:00Z","timestamp":1086048000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["Antimicrob Agents Chemother"],"published-print":{"date-parts":[[2004,6]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n          <jats:p>\n            We investigated the minimum exposure times of prazicuantel (PZQ) and albendazole sulfoxide (ABZSO) required for their activities against\n            <jats:italic>Taenia<\/jats:italic>\n            cysts in vitro as well as the 50 and 99% effective concentrations. The results showed that although the effects of both drugs are time and concentration dependent, ABZSO acts much slower and is less potent than PZQ.\n          <\/jats:p>","DOI":"10.1128\/aac.48.6.2302-2304.2004","type":"journal-article","created":{"date-parts":[[2004,5,21]],"date-time":"2004-05-21T18:38:42Z","timestamp":1085164722000},"page":"2302-2304","update-policy":"http:\/\/dx.doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":26,"title":["In Vitro Effects of Albendazole Sulfoxide and Praziquantel against\n            <i>Taenia solium<\/i>\n            and\n            <i>Taenia crassiceps<\/i>\n            Cysts"],"prefix":"10.1128","volume":"48","author":[{"given":"Francisca","family":"Palomares","sequence":"first","affiliation":[{"name":"Laboratorio de Neuropsicofarmacologi\u0301a"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Guadalupe","family":"Palencia","sequence":"additional","affiliation":[{"name":"Laboratorio de Neuroinmunologi\u0301a, Instituto Nacional de Neurologi\u0301a y Neurocirugi\u0301a 14269"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rodolfo","family":"Pe\u0301rez","sequence":"additional","affiliation":[{"name":"Laboratorio de Neuroinmunologi\u0301a, Instituto Nacional de Neurologi\u0301a y Neurocirugi\u0301a 14269"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dinora","family":"Gonza\u0301lez-Esquivel","sequence":"additional","affiliation":[{"name":"Laboratorio de Neuropsicofarmacologi\u0301a"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nelly","family":"Castro","sequence":"additional","affiliation":[{"name":"Laboratorio de Neuropsicofarmacologi\u0301a"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Helgi Jung","family":"Cook","sequence":"additional","affiliation":[{"name":"Laboratorio de Neuropsicofarmacologi\u0301a"},{"name":"Facultad de Qui\u0301mica, UNAM, Me\u0301xico, D.F., Me\u0301xico"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"235","reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1016\/0020-7519(95)00095-X","volume":"26","year":"1996","unstructured":"Casado, N., G. P\u00e9rez-Serrano, G. Denegri, and F. Rodr\u00edguez-Caabeiro. 1996. Development of a chemotherapic model for the in vitro screening of drugs against Echinococcus granulosus cysts: the effects of an albendazole-albendazole sulphoxide combination. Int. J. Parasitol.26:59-65.","journal-title":"Int. J. Parasitol."},{"key":"e_1_3_2_3_2","doi-asserted-by":"crossref","first-page":"815","DOI":"10.1016\/0035-9203(86)90392-5","volume":"80","year":"1986","unstructured":"Chinnery, J. B., and D. L. Morris. 1986. Effect of albendazole sulphoxide on viability of hydatid protoscoleces in vitro. Trans. R. Soc. Trop. Med. Hyg.80:815-817.","journal-title":"Trans. R. Soc. Trop. Med. Hyg."},{"key":"e_1_3_2_4_2","doi-asserted-by":"crossref","first-page":"543","DOI":"10.1007\/BF00932019","volume":"81","year":"1995","unstructured":"Da Silva, S. P., and F. Noel. 1995. Time course of the effect of praziquantel on Schistosoma masoni attachment in vitro: comparison with its effects on worm length and motility. Parasitol. Res.81:543-548.","journal-title":"Parasitol. Res."},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.43.5.1052"},{"key":"e_1_3_2_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/0169-4758(90)90227-U"},{"key":"e_1_3_2_7_2","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1016\/0020-7519(94)90029-9","volume":"24","year":"1994","unstructured":"P\u00e9rez-Serrano, J., N. Casado, and G. Denegri. 1994. The effects of albendazole and albendazole sulphoxide combination-therapy on Echinococcus granulosus in vitro.Int. J. Parasitol.24:219-224.","journal-title":"Int. J. Parasitol."},{"key":"e_1_3_2_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/0035-9203(88)90443-9"},{"key":"e_1_3_2_9_2","doi-asserted-by":"publisher","DOI":"10.1007\/PL00008526"}],"container-title":["Antimicrobial Agents and Chemotherapy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/AAC.48.6.2302-2304.2004","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/AAC.48.6.2302-2304.2004","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,2,21]],"date-time":"2022-02-21T18:21:39Z","timestamp":1645467699000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.asm.org\/doi\/10.1128\/AAC.48.6.2302-2304.2004"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2004,6]]},"references-count":8,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2004,6]]}},"alternative-id":["10.1128\/AAC.48.6.2302-2304.2004"],"URL":"https:\/\/doi.org\/10.1128\/aac.48.6.2302-2304.2004","relation":{},"ISSN":["0066-4804","1098-6596"],"issn-type":[{"value":"0066-4804","type":"print"},{"value":"1098-6596","type":"electronic"}],"subject":[],"published":{"date-parts":[[2004,6]]},"assertion":[{"value":"2003-09-10","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2004-02-08","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2004-06-01","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}