{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,6]],"date-time":"2026-03-06T18:46:48Z","timestamp":1772822808826,"version":"3.50.1"},"reference-count":27,"publisher":"American Society for Microbiology","issue":"7","license":[{"start":{"date-parts":[[2004,7,1]],"date-time":"2004-07-01T00:00:00Z","timestamp":1088640000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["Antimicrob Agents Chemother"],"published-print":{"date-parts":[[2004,7]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n          <jats:p>\n            Susceptibilities of\n            <jats:italic>Madurella mycetomatis<\/jats:italic>\n            against amphotericin B and itraconazole in vitro were determined by protocols based on NCCLS guidelines (visual reading) and a 2,3-bis (2-methoxy-4-nitro-5-sulfophenyl)-5-[(phenylamino) carbonyl]-2\n            <jats:italic>H<\/jats:italic>\n            -tetrazolium hydroxide (XTT) assay for fungal viability. The XTT assay was reproducible and sensitive for both antifungals. Itraconazole (MIC at which 50% of the isolates tested are inhibited [MIC\n            <jats:sub>50<\/jats:sub>\n            ]) of 0.06 to 0.13 mg\/liter) was superior to amphotericin B (MIC\n            <jats:sub>50<\/jats:sub>\n            of 0.5 to 1.0 mg\/liter).\n          <\/jats:p>","DOI":"10.1128\/aac.48.7.2742-2746.2004","type":"journal-article","created":{"date-parts":[[2004,6,23]],"date-time":"2004-06-23T22:18:08Z","timestamp":1088029088000},"page":"2742-2746","update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":73,"title":["In Vitro Susceptibilities of\n            <i>Madurella mycetomatis<\/i>\n            to Itraconazole and Amphotericin B Assessed by a Modified NCCLS Method and a Viability-Based 2,3-Bis(2-Methoxy-4-Nitro-5- Sulfophenyl)-5-[(Phenylamino)Carbonyl]-2\n            <i>H<\/i>\n            - Tetrazolium Hydroxide (XTT) Assay"],"prefix":"10.1128","volume":"48","author":[{"given":"Abdalla O. 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