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Mutations in\n            <jats:italic>parC<\/jats:italic>\n            , which encodes a subunit of topoisomerase IV, were associated with loss of susceptibility to sparfloxacin, moxifloxacin, and Bay-Y3118, but not ciprofloxacin. This is the first description of fluoroquinolone resistance in the spirochete phylum.\n          <\/jats:p>","DOI":"10.1128\/aac.49.10.4354-4357.2005","type":"journal-article","created":{"date-parts":[[2005,9,27]],"date-time":"2005-09-27T16:28:08Z","timestamp":1127838488000},"page":"4354-4357","update-policy":"http:\/\/dx.doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":11,"title":["<i>parC<\/i>\n            Mutations in Fluoroquinolone-Resistant\n            <i>Borrelia burgdorferi<\/i>"],"prefix":"10.1128","volume":"49","author":[{"given":"Kendal M.","family":"Galbraith","sequence":"first","affiliation":[{"name":"Division of Biological Sciences, The University of Montana, Missoula, Montana 59812"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amanda C.","family":"Ng","sequence":"additional","affiliation":[{"name":"Division of Biological Sciences, The University of Montana, Missoula, Montana 59812"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Betsy J.","family":"Eggers","sequence":"additional","affiliation":[{"name":"Division of Biological Sciences, The University of Montana, Missoula, Montana 59812"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Craig R.","family":"Kuchel","sequence":"additional","affiliation":[{"name":"Division of Biological Sciences, The University of Montana, Missoula, Montana 59812"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christian H.","family":"Eggers","sequence":"additional","affiliation":[{"name":"Division of Biological Sciences, The University of Montana, Missoula, Montana 59812"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D. Scott","family":"Samuels","sequence":"additional","affiliation":[{"name":"Division of Biological Sciences, The University of Montana, Missoula, Montana 59812"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"235","reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.3603026"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.72.11.6433-6445.2004"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.1006\/jmbi.1996.0274"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.33.6.886"},{"key":"e_1_3_2_6_2","doi-asserted-by":"publisher","DOI":"10.1128\/jcm.30.10.2692-2697.1992"},{"key":"e_1_3_2_7_2","doi-asserted-by":"publisher","DOI":"10.1093\/jac\/dkg269"},{"key":"e_1_3_2_8_2","doi-asserted-by":"publisher","DOI":"10.2174\/1568026033452537"},{"key":"e_1_3_2_9_2","doi-asserted-by":"publisher","DOI":"10.1128\/mmbr.61.3.377-392.1997"},{"key":"e_1_3_2_10_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2958.2004.04047.x"},{"key":"e_1_3_2_11_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2958.1994.tb00458.x"},{"key":"e_1_3_2_12_2","doi-asserted-by":"publisher","DOI":"10.1038\/37551"},{"key":"e_1_3_2_13_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.44.12.3351-3356.2000"},{"key":"e_1_3_2_14_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.74.11.4772"},{"key":"e_1_3_2_15_2","doi-asserted-by":"publisher","DOI":"10.3201\/eid0702.010239"},{"key":"e_1_3_2_16_2","first-page":"39","year":"1992","unstructured":"Huang, W. 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