{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,13]],"date-time":"2026-05-13T01:08:44Z","timestamp":1778634524008,"version":"3.51.4"},"reference-count":15,"publisher":"American Society for Microbiology","issue":"6","license":[{"start":{"date-parts":[[2005,6,1]],"date-time":"2005-06-01T00:00:00Z","timestamp":1117584000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["Antimicrob Agents Chemother"],"published-print":{"date-parts":[[2005,6]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:p>Peptide deformylase inhibitor LBM-415 and seven other drugs were tested against<jats:italic>Mycoplasma pneumoniae<\/jats:italic>(100 isolates),<jats:italic>Mycoplasma hominis<\/jats:italic>(20 isolates),<jats:italic>Mycoplasma fermentans<\/jats:italic>(10 isolates), and<jats:italic>Ureaplasma<\/jats:italic>species (50 isolates). LBM-415 was active against<jats:italic>M. pneumoniae<\/jats:italic>(MICs, \u22640.008 \u03bcg\/ml). It showed no activity against<jats:italic>M. hominis<\/jats:italic>and<jats:italic>M. fermentans<\/jats:italic>and modest activity against<jats:italic>Ureaplasma<\/jats:italic>spp.<\/jats:p>","DOI":"10.1128\/aac.49.6.2541-2542.2005","type":"journal-article","created":{"date-parts":[[2005,5,25]],"date-time":"2005-05-25T23:07:56Z","timestamp":1117062476000},"page":"2541-2542","update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":19,"title":["Comparative In Vitro Activities of Investigational Peptide Deformylase Inhibitor NVP LBM-415 and Other Agents against Human Mycoplasmas and Ureaplasmas"],"prefix":"10.1128","volume":"49","author":[{"given":"Ken B.","family":"Waites","sequence":"first","affiliation":[{"name":"Department of Pathology, University of Alabama at Birmingham, Birmingham, Alabama 35249"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nipun B.","family":"Reddy","sequence":"additional","affiliation":[{"name":"Department of Pathology, University of Alabama at Birmingham, Birmingham, Alabama 35249"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Donna M.","family":"Crabb","sequence":"additional","affiliation":[{"name":"Department of Pathology, University of Alabama at Birmingham, Birmingham, Alabama 35249"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lynn B.","family":"Duffy","sequence":"additional","affiliation":[{"name":"Department of Pathology, University of Alabama at Birmingham, Birmingham, Alabama 35249"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"235","reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1016\/S0732-8893(03)00162-7","volume":"48","year":"2004","unstructured":"Anderegg, T. R., and R. N. Jones. 2004. Disk diffusion quality control guidelines for NVP-PDF 713: a novel peptide deformylase inhibitor. Diagn. Microbiol. Infect. Dis.48:55-57.","journal-title":"Diagn. Microbiol. Infect. Dis."},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.45.4.1058-1064.2001"},{"key":"e_1_3_2_4_2","first-page":"275","year":"1979","unstructured":"Clyde, W. A., Jr. 1979. Mycoplasma pneumoniae infections of man, p. 275-306. In J. G. Tully and R. F. Whitcomb (ed.), The mycoplasmas II. Human and animal mycoplasmas, vol. II. Academic Press, New York, N.Y.","journal-title":"The mycoplasmas II. Human and animal mycoplasmas"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.48.10.4033-4036.2004"},{"key":"e_1_3_2_6_2","first-page":"29","volume":"45","year":"2000","unstructured":"Duffy, L. B., D. Crabb, K. Searcey, and M. C. Kempf. 2000. Comparative potency of gemifloxacin, new quinolones, macrolides, tetracycline and clindamycin against Mycoplasma spp. J. Antimicrob. Chemother.45(Suppl. 1):29-33.","journal-title":"J. Antimicrob. Chemother."},{"key":"e_1_3_2_7_2","doi-asserted-by":"crossref","first-page":"415","DOI":"10.1517\/14728222.5.3.415","volume":"5","year":"2001","unstructured":"Giglione, C., and T. Meinnel. 2001. Resistance to anti-peptide deformylase drugs. Expert Opin. Ther. Targets5:415-418.","journal-title":"Expert Opin. Ther. Targets"},{"key":"e_1_3_2_8_2","doi-asserted-by":"crossref","first-page":"1197","DOI":"10.1046\/j.1365-2958.2000.01908.x","volume":"36","year":"2000","unstructured":"Giglione, C., M. Pierre, and T. Meinnel. 2000. Peptide deformylase as a target for new generation, broad spectrum antimicrobial agents. Mol. Microbiol.36:1197-1205.","journal-title":"Mol. 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