{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,9]],"date-time":"2025-10-09T06:41:53Z","timestamp":1759992113008},"reference-count":0,"publisher":"American Society for Microbiology","issue":"2","license":[{"start":{"date-parts":[[1976,2,1]],"date-time":"1976-02-01T00:00:00Z","timestamp":191980800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["Antimicrob Agents Chemother"],"published-print":{"date-parts":[[1976,2]]},"abstract":"<jats:p>\n            One hundred seventy-three strains of shigellae (113\n            <jats:italic>Shigella sonnei<\/jats:italic>\n            , 56\n            <jats:italic>S. flexneri<\/jats:italic>\n            , and four others) isolated in Houston during 1974 were tested for susceptibility to commonly used and newer antimicrobial agents. Forty-five percent of\n            <jats:italic>S. sonnei<\/jats:italic>\n            strains were susceptible to ampicillin, whereas 93% of\n            <jats:italic>S. flexneri<\/jats:italic>\n            strains were susceptible to that agent.\n            <jats:italic>S. sonnei<\/jats:italic>\n            and\n            <jats:italic>S. flexneri<\/jats:italic>\n            strains were equally susceptible to tetracycline (35 and 33%, respectively). All 173 strains were uniformly susceptible to quinoline drugs (cinoxacin, oxolinic acid, and nalidixic acid) and to trimethoprim-sulfamethoxazole. This study supports recent suggestions that the initial therapy of bacillary dysentery no longer should be ampicillin or tetracycline. It remains for field testing to determine whether quinoline agents or trimethoprim-sulfamethoxazole will be the treatment of choice.\n          <\/jats:p>","DOI":"10.1128\/aac.9.2.288","type":"journal-article","created":{"date-parts":[[2012,6,27]],"date-time":"2012-06-27T23:57:02Z","timestamp":1340841422000},"page":"288-291","update-policy":"http:\/\/dx.doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":14,"title":["Antimicrobial Susceptibilities of Shigellae Isolated in Houston, Texas, in 1974"],"prefix":"10.1128","volume":"9","author":[{"given":"Patricia A.","family":"Byers","sequence":"first","affiliation":[{"name":"Program in Infectious Diseases and Clinical Microbiology, The University of Texas Health Science Center at Houston \u2013 Medical School, Houston, Texas 77025"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Herbert L.","family":"Dupont","sequence":"additional","affiliation":[{"name":"Program in Infectious Diseases and Clinical Microbiology, The University of Texas Health Science Center at Houston \u2013 Medical School, Houston, Texas 77025"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Millicent C.","family":"Goldschmidt","sequence":"additional","affiliation":[{"name":"Program in Infectious Diseases and Clinical Microbiology, The University of Texas Health Science Center at Houston \u2013 Medical School, Houston, Texas 77025"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"235","container-title":["Antimicrobial Agents and Chemotherapy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/AAC.9.2.288","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/AAC.9.2.288","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,2,21]],"date-time":"2022-02-21T13:22:02Z","timestamp":1645449722000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.asm.org\/doi\/10.1128\/AAC.9.2.288"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1976,2]]},"references-count":0,"journal-issue":{"issue":"2","published-print":{"date-parts":[[1976,2]]}},"alternative-id":["10.1128\/AAC.9.2.288"],"URL":"https:\/\/doi.org\/10.1128\/aac.9.2.288","relation":{},"ISSN":["0066-4804","1098-6596"],"issn-type":[{"value":"0066-4804","type":"print"},{"value":"1098-6596","type":"electronic"}],"subject":[],"published":{"date-parts":[[1976,2]]},"assertion":[{"value":"1976-02-01","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}