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A total of 31 independent isolates confirmed as\n            <jats:named-content content-type=\"genus-species\">V. cholerae<\/jats:named-content>\n            were collected from water, sediment, and oysters in 2008 and 2009 from the Great Bay Estuary (GBE) in New Hampshire, a location where the organism has never been detected. Environmental analyses suggested that abundance correlates most strongly with rainfall events, as determined from data averaged over several days prior to collection. Phenotyping, genotyping, and multilocus sequence analysis (MLSA) revealed a highly diverse endemic population, with clones recurring in both years. Certain isolates were closely related to toxigenic O1 strains, yet no virulence genes were detected. Multiple statistical tests revealed evidence of recombination among strains that contributed to allelic diversity equally as mutation. This relatively isolated population discovered on the northern limit of detection for\n            <jats:named-content content-type=\"genus-species\">V. cholerae<\/jats:named-content>\n            can serve as a model of natural population dynamics that augments predictive models for disease emergence.\n          <\/jats:p>","DOI":"10.1128\/aem.00378-11","type":"journal-article","created":{"date-parts":[[2011,9,17]],"date-time":"2011-09-17T02:06:58Z","timestamp":1316225218000},"page":"7568-7575","update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":37,"title":["Ecology and Genetic Structure of a Northern Temperate Vibrio cholerae Population Related to Toxigenic Isolates"],"prefix":"10.1128","volume":"77","author":[{"given":"Brian M.","family":"Schuster","sequence":"first","affiliation":[{"name":"University of New Hampshire, Department of Molecular, Cellular, and Biomedical Sciences, Durham, New Hampshire 03824"},{"name":"University of New Hampshire, Graduate Program in Microbiology, Durham, New Hampshire 03824"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anna L.","family":"Tyzik","sequence":"additional","affiliation":[{"name":"University of New Hampshire, Department of Molecular, Cellular, and Biomedical Sciences, Durham, New Hampshire 03824"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rachel A.","family":"Donner","sequence":"additional","affiliation":[{"name":"University of New Hampshire, Department of Molecular, Cellular, and Biomedical Sciences, Durham, New Hampshire 03824"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Megan J.","family":"Striplin","sequence":"additional","affiliation":[{"name":"University of New Hampshire, Department of Molecular, Cellular, and Biomedical Sciences, Durham, New Hampshire 03824"},{"name":"University of New Hampshire, Graduate Program in Microbiology, Durham, New Hampshire 03824"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Salvador","family":"Almagro-Moreno","sequence":"additional","affiliation":[{"name":"Dartmouth Medical School, Department of Microbiology and Immunology, Hanover, New Hampshire 03755"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stephen H.","family":"Jones","sequence":"additional","affiliation":[{"name":"University of New Hampshire, Graduate Program in Microbiology, Durham, New Hampshire 03824"},{"name":"University of New Hampshire, Department of Natural Resources and the Environment, Durham, New Hampshire 03824"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vaughn S.","family":"Cooper","sequence":"additional","affiliation":[{"name":"University of New Hampshire, Department of Molecular, Cellular, and Biomedical Sciences, Durham, New Hampshire 03824"},{"name":"University of New Hampshire, Graduate Program in Microbiology, Durham, New Hampshire 03824"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cheryl A.","family":"Whistler","sequence":"additional","affiliation":[{"name":"University of New Hampshire, Department of Molecular, Cellular, and Biomedical Sciences, Durham, New Hampshire 03824"},{"name":"University of New Hampshire, Graduate Program in Microbiology, Durham, New Hampshire 03824"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"235","reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/0140-6736(93)90481-U"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.00279-09"},{"key":"e_1_3_2_4_2","volume-title":"Current protocols in molecular biology","author":"Ausubel F.","year":"1990","unstructured":"AusubelF.. 1990. 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