{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T08:07:04Z","timestamp":1790842024594,"version":"4.1.0"},"reference-count":50,"publisher":"American Society for Microbiology","issue":"16","license":[{"start":{"date-parts":[[2009,8,15]],"date-time":"2009-08-15T00:00:00Z","timestamp":1250294400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["Appl Environ Microbiol"],"published-print":{"date-parts":[[2009,8,15]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>\n                    A new family of synthetic, membrane-active, ultrashort lipopeptides composed of only four amino acids linked to fatty acids was tested for the ability to induce systemic resistance and defense responses in plants. We found that two peptides wherein the third residue is a\n                    <jats:sc>d<\/jats:sc>\n                    -enantiomer (italic), C\n                    <jats:sub>16<\/jats:sub>\n                    -KK\n                    <jats:italic>K<\/jats:italic>\n                    K and C\n                    <jats:sub>16<\/jats:sub>\n                    -KL\n                    <jats:italic>L<\/jats:italic>\n                    K, can induce medium alkalinization of tobacco suspension-cultured cells and expression of defense-related genes in cucumber and\n                    <jats:italic>Arabidopsis<\/jats:italic>\n                    seedlings. Moreover, these compounds can prime systemic induction of antimicrobial compounds in cucumber leaves similarly to the plant-beneficial fungus\n                    <jats:italic>Trichoderma asperellum<\/jats:italic>\n                    T203 and provide systemic protection against the phytopathogens\n                    <jats:italic>Botrytis cinerea<\/jats:italic>\n                    B05,\n                    <jats:italic>Pseudomonas syringae<\/jats:italic>\n                    pv.\n                    <jats:italic>lachrimans<\/jats:italic>\n                    , and\n                    <jats:italic>P. syringae<\/jats:italic>\n                    pv.\n                    <jats:italic>tomato<\/jats:italic>\n                    DC3000. Thus, short cationic lipopeptides are a new category of compounds with potentially high utility in the induction of systemic resistance in plants.\n                  <\/jats:p>","DOI":"10.1128\/aem.00724-09","type":"journal-article","created":{"date-parts":[[2009,6,19]],"date-time":"2009-06-19T21:46:03Z","timestamp":1245447963000},"page":"5373-5379","update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":42,"title":["Synthetic Ultrashort Cationic Lipopeptides Induce Systemic Plant Defense Responses against Bacterial and Fungal Pathogens"],"prefix":"10.1128","volume":"75","author":[{"given":"Yariv","family":"Brotman","sequence":"first","affiliation":[{"name":"Department of Plant Pathology and Microbiology, The Smith Faculty of Agriculture, Food and Environment, The Hebrew University of Jerusalem, Rehovot 76100, Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arik","family":"Makovitzki","sequence":"additional","affiliation":[{"name":"Department of Biological Chemistry, Weizmann Institute of Science, Rehovot 76100, Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yechiel","family":"Shai","sequence":"additional","affiliation":[{"name":"Department of Biological Chemistry, Weizmann Institute of Science, Rehovot 76100, Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ilan","family":"Chet","sequence":"additional","affiliation":[{"name":"Department of Plant Pathology and Microbiology, The Smith Faculty of Agriculture, Food and Environment, The Hebrew University of Jerusalem, Rehovot 76100, Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ada","family":"Viterbo","sequence":"additional","affiliation":[{"name":"Department of Plant Pathology and Microbiology, The Smith Faculty of Agriculture, Food and Environment, The Hebrew University of Jerusalem, Rehovot 76100, Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"235","reference":[{"key":"e_1_3_2_2_2","first-page":"386","year":"2006","unstructured":"Anderson, A. 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