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In particular,\n            <jats:named-content content-type=\"genus-species\">Staphylococcus aureus<\/jats:named-content>\n            is a common and dangerous pathogen, and\n            <jats:named-content content-type=\"genus-species\">Staphylococcus epidermidis<\/jats:named-content>\n            is a ubiquitous skin commensal and opportunistic pathogen. Treatment of infections caused by staphylococci has become more difficult because of the emergence of multidrug-resistant strains as well as biofilm formation. In this study, we found that all tested\n            <jats:named-content content-type=\"genus-species\">S. aureus<\/jats:named-content>\n            ,\n            <jats:named-content content-type=\"genus-species\">S. epidermidis<\/jats:named-content>\n            ,\n            <jats:named-content content-type=\"genus-species\">Staphylococcus haemolyticus<\/jats:named-content>\n            , and\n            <jats:named-content content-type=\"genus-species\">Staphylococcus hominis<\/jats:named-content>\n            strains were sensitive to the phage lysin LysGH15 (MICs ranging from 8 to 32 \u03bcg\/ml). More importantly, LysGH15 not only prevented biofilm formation by these staphylococci but also disrupted 24-h and 72-h biofilms. Furthermore, the\n            <jats:italic>in vivo<\/jats:italic>\n            efficacy of LysGH15 was demonstrated in a mouse model of\n            <jats:named-content content-type=\"genus-species\">S. epidermidis<\/jats:named-content>\n            bacteremia. Thus, LysGH15 exhibits therapeutic potential for treating biofilm-related or non-biofilm-related infections caused by diverse staphylococci.\n          <\/jats:p>","DOI":"10.1128\/aem.00886-18","type":"journal-article","created":{"date-parts":[[2018,5,17]],"date-time":"2018-05-17T09:40:51Z","timestamp":1526550051000},"update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":52,"title":["Antibacterial Effects of Phage Lysin LysGH15 on Planktonic Cells and Biofilms of Diverse Staphylococci"],"prefix":"10.1128","volume":"84","author":[{"given":"Yufeng","family":"Zhang","sequence":"first","affiliation":[{"name":"Key Laboratory of Zoonosis, Ministry of Education, College of Veterinary Medicine, Jilin University, Changchun, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mengjun","family":"Cheng","sequence":"additional","affiliation":[{"name":"Key Laboratory of Zoonosis, Ministry of Education, College of 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