{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,13]],"date-time":"2026-06-13T03:09:16Z","timestamp":1781320156421,"version":"3.54.1"},"reference-count":59,"publisher":"American Society for Microbiology","issue":"1","license":[{"start":{"date-parts":[[2022,1,11]],"date-time":"2022-01-11T00:00:00Z","timestamp":1641859200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2022,1,11]],"date-time":"2022-01-11T00:00:00Z","timestamp":1641859200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"funder":[{"DOI":"10.13039\/100008370","name":"National Pork Board","doi-asserted-by":"publisher","award":["#18-180"],"award-info":[{"award-number":["#18-180"]}],"id":[{"id":"10.13039\/100008370","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["Appl Environ Microbiol"],"published-print":{"date-parts":[[2022,1,11]]},"abstract":"<jats:p>Despite a recognized need for more longitudinal studies to assess the effects of antimicrobial use on resistance in food animals, they remain sparse in the literature, and most longitudinal studies of pigs have been observational. The current experimental study had the advantages of greater control of potential confounding, precise measurement of antimicrobial exposures which varied markedly between groups and tracking of pigs until market age.<\/jats:p>","DOI":"10.1128\/aem.00970-21","type":"journal-article","created":{"date-parts":[[2021,10,13]],"date-time":"2021-10-13T17:33:13Z","timestamp":1634146393000},"update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":6,"title":["Evaluation of the Impact of Antimicrobial Use Protocols in Porcine Reproductive and Respiratory Syndrome Virus-Infected Swine on Phenotypic Antimicrobial Resistance Patterns"],"prefix":"10.1128","volume":"88","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0787-4985","authenticated-orcid":true,"given":"Carissa A.","family":"Odland","sequence":"first","affiliation":[{"name":"Pipestone Veterinary Services, Pipestone, Minnesota, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roy","family":"Edler","sequence":"additional","affiliation":[{"name":"Pipestone Applied Research, Pipestone, Minnesota, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Noelle R.","family":"Noyes","sequence":"additional","affiliation":[{"name":"University of Minnesota, Saint Paul, Minnesota, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Scott A.","family":"Dee","sequence":"additional","affiliation":[{"name":"Pipestone Applied Research, Pipestone, Minnesota, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joel","family":"Nerem","sequence":"additional","affiliation":[{"name":"Pipestone Applied Research, Pipestone, Minnesota, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter R.","family":"Davies","sequence":"additional","affiliation":[{"name":"University of Minnesota, Saint Paul, Minnesota, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"235","reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.1892\/0891-6640"},{"key":"e_1_3_3_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/S2542-5196(17)30141-9"},{"key":"e_1_3_3_4_2","doi-asserted-by":"publisher","DOI":"10.1128\/microbiolspec.ARBA-0009-2017"},{"key":"e_1_3_3_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijantimicag.2018.04.005"},{"key":"e_1_3_3_6_2","doi-asserted-by":"publisher","DOI":"10.3390\/antibiotics9020049"},{"key":"e_1_3_3_7_2","doi-asserted-by":"publisher","DOI":"10.1093\/jac\/dkr430"},{"key":"e_1_3_3_8_2","doi-asserted-by":"publisher","DOI":"10.15585\/mmwr.mm6737a3"},{"key":"e_1_3_3_9_2","doi-asserted-by":"publisher","DOI":"10.1111\/evj.12785"},{"key":"e_1_3_3_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.vas.2019.100058"},{"key":"e_1_3_3_11_2","unstructured":"DANMAP. 2018. Use of antimicrobial agents and occurrence of antimicrobial resistance in bacteria from food animals food and humans in Denmark. https:\/\/www.danmap.org\/reports\/2018."},{"key":"e_1_3_3_12_2","doi-asserted-by":"publisher","DOI":"10.1093\/jac\/dky503"},{"key":"e_1_3_3_13_2","doi-asserted-by":"publisher","DOI":"10.1111\/zph.12760"},{"key":"e_1_3_3_14_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.prevetmed.2013.12.007"},{"key":"e_1_3_3_15_2","doi-asserted-by":"publisher","DOI":"10.1089\/mdr.2018.0154"},{"key":"e_1_3_3_16_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1120238109"},{"key":"e_1_3_3_17_2","doi-asserted-by":"publisher","DOI":"10.1089\/mdr.2008.0821"},{"key":"e_1_3_3_18_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-019-40496-8"},{"key":"e_1_3_3_19_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.vetmic.2017.07.005"},{"key":"e_1_3_3_20_2","doi-asserted-by":"publisher","DOI":"10.1111\/jam.14721"},{"key":"e_1_3_3_21_2","doi-asserted-by":"publisher","DOI":"10.3389\/fvets.2020.00255"},{"key":"e_1_3_3_22_2","doi-asserted-by":"publisher","DOI":"10.1089\/fpd.2018.2551"},{"key":"e_1_3_3_23_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.prevetmed.2019.02.008"},{"key":"e_1_3_3_24_2","doi-asserted-by":"publisher","DOI":"10.1128\/AEM.02624-07"},{"key":"e_1_3_3_25_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.prevetmed.2009.11.014"},{"key":"e_1_3_3_26_2","doi-asserted-by":"publisher","DOI":"10.1186\/s12866-016-0823-3"},{"key":"e_1_3_3_27_2","doi-asserted-by":"publisher","DOI":"10.1186\/s12866-019-1619-z"},{"key":"e_1_3_3_28_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-020-58659-3"},{"key":"e_1_3_3_29_2","doi-asserted-by":"publisher","DOI":"10.1080\/01652176.1991.9694296"},{"key":"e_1_3_3_30_2","doi-asserted-by":"crossref","first-page":"72","DOI":"10.54846\/jshap\/754","article-title":"Assessment of the economic impact of porcine reproductive and respiratory syndrome virus on U.S pork producers","volume":"21","author":"Holtkamp DJ","year":"2013","unstructured":"Holtkamp DJ, Kliebenstein JB, Neumann EJ, Zimmerman JJ, Rotto H, Yoder TK, Wang C, Yeske P, Mowrer C, Haley C. 2013. Assessment of the economic impact of porcine reproductive and respiratory syndrome virus on U.S pork producers. Swine Health Prod 21:72\u201384.","journal-title":"Swine Health Prod"},{"key":"e_1_3_3_31_2","doi-asserted-by":"publisher","DOI":"10.1017\/S1466252311000120"},{"key":"e_1_3_3_32_2","volume-title":"Swine 2012, Part II: reference of swine health and health management in the United States, 2012.","author":"USDA","year":"2015","unstructured":"USDA. 2015. Swine 2012, Part II: reference of swine health and health management in the United States, 2012. USDA\u2013APHIS\u2013VS\u2013CEAH\u2013NAHMS, Fort Collins, CO."},{"key":"e_1_3_3_33_2","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.01251-17"},{"key":"e_1_3_3_34_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0208430"},{"key":"e_1_3_3_35_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.virusres.2010.08.015"},{"key":"e_1_3_3_36_2","unstructured":"U.S. Food and Drug Administration\u2013Center for Veterinary Medicine. 2020. 2019 summary report on antimicrobials sold or distributed for use in food-producing animals. U.S. FDA Silver Spring MD."},{"key":"e_1_3_3_37_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(15)00473-0"},{"key":"e_1_3_3_38_2","unstructured":"Anderson M Clift C Schulze K Sagan A Nahrgang S Ait Ouakrim D Mossialos E 2019. Averting the AMR crisis: What are the avenues for policy action for countries in Europe? European Observatory on Health Systems and Policies Copenhagen (Denmark). https:\/\/europepmc.org\/article\/med\/31287637."},{"key":"e_1_3_3_39_2","doi-asserted-by":"publisher","DOI":"10.2147\/IDR.S173867"},{"key":"e_1_3_3_40_2","doi-asserted-by":"publisher","DOI":"10.1186\/s12879-019-4630-y"},{"key":"e_1_3_3_41_2","doi-asserted-by":"publisher","DOI":"10.1146\/annurev-animal-072020-080638"},{"key":"e_1_3_3_42_2","doi-asserted-by":"publisher","DOI":"10.1186\/s12915-019-0692-y"},{"key":"e_1_3_3_43_2","doi-asserted-by":"publisher","DOI":"10.1089\/mdr.2014.0037"},{"key":"e_1_3_3_44_2","doi-asserted-by":"publisher","DOI":"10.1093\/clinids\/7.5.702"},{"key":"e_1_3_3_45_2","unstructured":"World Organisation for Animal Health. 2020. OIE annual report on antimicrobial agents intended for use in animals\u2014fourth report. https:\/\/www.oie.int\/fileadmin\/Home\/eng\/Our_scientific_expertise\/docs\/pdf\/AMR\/A_Fourth_Annual_Report_AMR.pdf."},{"key":"e_1_3_3_46_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.aaw1944"},{"key":"e_1_3_3_47_2","doi-asserted-by":"publisher","DOI":"10.1111\/tbed.13528"},{"key":"e_1_3_3_48_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.rvsc.2019.11.010"},{"key":"e_1_3_3_49_2","doi-asserted-by":"publisher","DOI":"10.1186\/s12917-019-2162-8"},{"key":"e_1_3_3_50_2","doi-asserted-by":"publisher","DOI":"10.1021\/es901221x"},{"key":"e_1_3_3_51_2","doi-asserted-by":"publisher","DOI":"10.1038\/s42003-020-0966-5"},{"key":"e_1_3_3_52_2","doi-asserted-by":"publisher","DOI":"10.1111\/jvp.12369"},{"key":"e_1_3_3_53_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0167-5877(97)00095-0"},{"key":"e_1_3_3_54_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.00670-13"},{"key":"e_1_3_3_55_2","doi-asserted-by":"crossref","first-page":"345","DOI":"10.54846\/jshap\/699","article-title":"A one-night downtime period prevents the spread of porcine reproductive and respiratory syndrome virus and Mycoplasma hyopneumoniae by personnel and fomites (boots and coveralls)","volume":"19","author":"Pitkin A","year":"2011","unstructured":"Pitkin A, Otake S, Dee S. 2011. A one-night downtime period prevents the spread of porcine reproductive and respiratory syndrome virus and Mycoplasma hyopneumoniae by personnel and fomites (boots and coveralls). J Swine Health Prod 19:345\u2013348.","journal-title":"J Swine Health Prod"},{"key":"e_1_3_3_56_2","doi-asserted-by":"crossref","first-page":"188","DOI":"10.54846\/jshap\/747","article-title":"Impact of a husbandry education program on nursery pig mortality, productivity, and treatment cost","volume":"21","author":"Galina Pantoja L","year":"2013","unstructured":"Galina Pantoja L, Kuhn M, Hoover T, Amodie D, Weigel D, Dice C, Moeller T, Farrand E. 2013. Impact of a husbandry education program on nursery pig mortality, productivity, and treatment cost. J Swine Health Prod 21:188\u2013194.","journal-title":"J Swine Health Prod"},{"key":"e_1_3_3_57_2","doi-asserted-by":"crossref","first-page":"296","DOI":"10.54846\/jshap\/831","article-title":"Individual Pig Care program improves productive performance and animal health in nursery-growing pigs","volume":"22","author":"Pineiro C","year":"2014","unstructured":"Pineiro C, Morales J, Dereu A, Wuyts N, Azlor O, Vizcaino E, Doncecchi P. 2014. Individual Pig Care program improves productive performance and animal health in nursery-growing pigs. J Swine Health Prod 22:296\u2013299.","journal-title":"J Swine Health Prod"},{"key":"e_1_3_3_58_2","doi-asserted-by":"publisher","DOI":"10.17226\/13298"},{"key":"e_1_3_3_59_2","doi-asserted-by":"publisher","DOI":"10.2527\/2000.7841010x"},{"key":"e_1_3_3_60_2","unstructured":"CDC\u2014National Center for Emerging and Zoonotic Infectious Diseases (NCEZID) Division of Foodborne Waterborne and Environmental Diseases (DFWED). March 2019. Antibiotics tested by NARMS. https:\/\/www.cdc.gov\/narms\/antibiotics-tested.html. Accessed April 2021."}],"container-title":["Applied and Environmental Microbiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/AEM.00970-21","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/AEM.00970-21","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,9,9]],"date-time":"2024-09-09T22:15:52Z","timestamp":1725920152000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.asm.org\/doi\/10.1128\/AEM.00970-21"}},"subtitle":[],"editor":[{"given":"Christopher A.","family":"Elkins","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2022,1,11]]},"references-count":59,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2022,1,11]]}},"alternative-id":["10.1128\/AEM.00970-21"],"URL":"https:\/\/doi.org\/10.1128\/aem.00970-21","relation":{},"ISSN":["0099-2240","1098-5336"],"issn-type":[{"value":"0099-2240","type":"print"},{"value":"1098-5336","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,1,11]]},"assertion":[{"value":"2021-05-22","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-09-09","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-01-11","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e00970-21"}}