{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T18:50:49Z","timestamp":1792003849030,"version":"4.4.0"},"reference-count":58,"publisher":"American Society for Microbiology","issue":"21","license":[{"start":{"date-parts":[[2018,11,1]],"date-time":"2018-11-01T00:00:00Z","timestamp":1541030400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"funder":[{"name":"German Federal Ministry of Education and Research","award":["03Z22DN11"],"award-info":[{"award-number":["03Z22DN11"]}]},{"DOI":"10.13039\/501100001659","name":"Deutsche Forschungsgemeinschaft","doi-asserted-by":"publisher","award":["DFG-TRR34"],"award-info":[{"award-number":["DFG-TRR34"]}],"id":[{"id":"10.13039\/501100001659","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["Appl Environ Microbiol"],"published-print":{"date-parts":[[2018,11]]},"abstract":"<jats:p>Microbial communities are an increasing problem in medicine but also in industry. Thus, an efficient and rapid removal of biofilms is becoming increasingly important. With the aid of the kINPen09, a radiofrequency plasma jet (RFPJ) instrument, decisive new findings on the effects of plasma on<jats:named-content content-type=\"genus-species\">C. albicans<\/jats:named-content>biofilms were obtained. This work showed that the inactivation of biofilms takes place mainly on the bottom, which in turn offers new possibilities for the removal of biofilms by other strategies, e.g., mechanical treatment. This result demonstrated that nonthermal atmospheric pressure plasma is well suited for biofilm decontamination.<\/jats:p>","DOI":"10.1128\/aem.01163-18","type":"journal-article","created":{"date-parts":[[2018,8,27]],"date-time":"2018-08-27T13:23:40Z","timestamp":1535376220000},"update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":35,"title":["Nonthermal Plasma Jet Treatment Negatively Affects the Viability and Structure of Candida albicans SC5314 Biofilms"],"prefix":"10.1128","volume":"84","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0786-5456","authenticated-orcid":false,"given":"O.","family":"Handorf","sequence":"first","affiliation":[{"name":"Leibniz Institute for Plasma Science and Technology (INP), Greifswald, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3533-2713","authenticated-orcid":false,"given":"T.","family":"Weihe","sequence":"additional","affiliation":[{"name":"Leibniz Institute for Plasma Science and Technology (INP), Greifswald, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8773-8862","authenticated-orcid":false,"given":"S.","family":"Bekeschus","sequence":"additional","affiliation":[{"name":"Leibniz Institute for Plasma Science and Technology (INP), Greifswald, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5975-2819","authenticated-orcid":false,"given":"A. C.","family":"Graf","sequence":"additional","affiliation":[{"name":"Ernst Moritz Arndt University, Microbial Physiology and Molecular Biology, Greifswald, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0691-3700","authenticated-orcid":false,"given":"U.","family":"Schnabel","sequence":"additional","affiliation":[{"name":"Leibniz Institute for Plasma Science and Technology (INP), Greifswald, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"K.","family":"Riedel","sequence":"additional","affiliation":[{"name":"Ernst Moritz Arndt University, Microbial Physiology and Molecular Biology, Greifswald, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5782-3345","authenticated-orcid":false,"given":"J.","family":"Ehlbeck","sequence":"additional","affiliation":[{"name":"Leibniz Institute for Plasma Science and Technology (INP), Greifswald, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"235","reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1109\/TPAMI.2016.2574706"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.3390\/pathogens7010015"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2621.1988.tb09321.x"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.4315\/0362-028X-53.9.742"},{"key":"e_1_3_2_6_2","doi-asserted-by":"publisher","DOI":"10.1080\/08927019109378226"},{"key":"e_1_3_2_7_2","doi-asserted-by":"publisher","DOI":"10.1093\/femsre\/fuw002"},{"key":"e_1_3_2_8_2","doi-asserted-by":"publisher","DOI":"10.1038\/nrd1008"},{"key":"e_1_3_2_9_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00772-003-0319-y"},{"key":"e_1_3_2_10_2","first-page":"239","article-title":"Chronische Wunden - Ulcus cruris, diabetisches Fu\u00dfsyndrom, Dekubitus, Verbrennungen","volume":"2","author":"Lauterbach S","year":"2006","unstructured":"Lauterbach S. 2006. Chronische Wunden - Ulcus cruris, diabetisches Fu\u00dfsyndrom, Dekubitus, Verbrennungen. PZ Prisma 2:239.","journal-title":"PZ Prisma"},{"key":"e_1_3_2_11_2","volume-title":"Candida and candidiasis","author":"Calderone RA","year":"2012","unstructured":"Calderone RA, Clancy C. 2012. Candida and candidiasis, 2nd ed. ASM Press, Washington, DC.","edition":"2"},{"key":"e_1_3_2_12_2","doi-asserted-by":"publisher","DOI":"10.4161\/viru.22913"},{"key":"e_1_3_2_13_2","doi-asserted-by":"publisher","DOI":"10.1128\/CMR.00029-06"},{"key":"e_1_3_2_14_2","doi-asserted-by":"publisher","DOI":"10.3109\/10408410903241444"},{"key":"e_1_3_2_15_2","doi-asserted-by":"publisher","DOI":"10.2174\/138945006776359421"},{"key":"e_1_3_2_16_2","volume-title":"Candida and candidiasis","author":"Calderone RA","year":"2002","unstructured":"Calderone RA. 2002. Candida and candidiasis. ASM Press, Washington, DC."},{"key":"e_1_3_2_17_2","first-page":"54","article-title":"Candida albicans importance to denture wearers. A literature review","volume":"17","author":"Gleiznys A","year":"2015","unstructured":"Gleiznys A, Zdanaviciene E, Zilinskas J. 2015. Candida albicans importance to denture wearers. A literature review. Stomatologija 17:54\u201366.","journal-title":"Stomatologija"},{"key":"e_1_3_2_18_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1741-2358.2011.00506.x"},{"key":"e_1_3_2_19_2","doi-asserted-by":"publisher","DOI":"10.1067\/mpr.2002.121203"},{"key":"e_1_3_2_20_2","doi-asserted-by":"publisher","DOI":"10.1128\/CMR.13.4.547-558.2000"},{"key":"e_1_3_2_21_2","doi-asserted-by":"publisher","DOI":"10.4103\/0975-7406.155902"},{"key":"e_1_3_2_22_2","doi-asserted-by":"publisher","DOI":"10.3389\/fmicb.2017.00659"},{"key":"e_1_3_2_23_2","doi-asserted-by":"publisher","DOI":"10.1186\/s12866-017-1031-5"},{"key":"e_1_3_2_24_2","doi-asserted-by":"publisher","DOI":"10.1093\/femsre\/fuw030"},{"key":"e_1_3_2_25_2","doi-asserted-by":"publisher","DOI":"10.1093\/femsre\/fux010"},{"key":"e_1_3_2_26_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF01569816"},{"key":"e_1_3_2_27_2","doi-asserted-by":"publisher","DOI":"10.1021\/bm800269h"},{"key":"e_1_3_2_28_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1574-6976.2008.00150.x"},{"key":"e_1_3_2_29_2","doi-asserted-by":"publisher","DOI":"10.1093\/jac\/dkq136"},{"key":"e_1_3_2_30_2","doi-asserted-by":"publisher","DOI":"10.1086\/375081"},{"key":"e_1_3_2_31_2","doi-asserted-by":"publisher","DOI":"10.4103\/jispcd.JISPCD_512_16"},{"key":"e_1_3_2_32_2","doi-asserted-by":"publisher","DOI":"10.1007\/s40735-015-0007-y"},{"key":"e_1_3_2_33_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijantimicag.2015.02.026"},{"key":"e_1_3_2_34_2","doi-asserted-by":"publisher","DOI":"10.1099\/jmm.0.020263-0"},{"key":"e_1_3_2_35_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0099300"},{"key":"e_1_3_2_36_2","doi-asserted-by":"publisher","DOI":"10.1002\/ppap.200400078"},{"key":"e_1_3_2_37_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.304.5676.1421b"},{"key":"e_1_3_2_38_2","doi-asserted-by":"publisher","DOI":"10.3389\/fmicb.2018.00537"},{"key":"e_1_3_2_39_2","doi-asserted-by":"publisher","DOI":"10.1109\/TPS.2005.844524"},{"key":"e_1_3_2_40_2","doi-asserted-by":"publisher","DOI":"10.1109\/TPS.2006.878431"},{"key":"e_1_3_2_41_2","doi-asserted-by":"publisher","DOI":"10.1088\/1367-2630\/11\/11\/115020"},{"key":"e_1_3_2_42_2","doi-asserted-by":"publisher","DOI":"10.1063\/1.3020223"},{"key":"e_1_3_2_43_2","doi-asserted-by":"publisher","DOI":"10.1088\/1367-2630\/12\/7\/073039"},{"key":"e_1_3_2_44_2","doi-asserted-by":"publisher","DOI":"10.3205\/dgkh000201"},{"key":"e_1_3_2_45_2","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1515\/chem-2015-0028","article-title":"Influence of a plasma jet on the viability of Candida albicans","volume":"13","author":"Moravsky L","year":"2015","unstructured":"Moravsky L, Klas M, Machova E, Pisklova K, Matejcik S. 2015. Influence of a plasma jet on the viability of Candida albicans. Open Chem 13:257\u2013262.","journal-title":"Open Chem"},{"key":"e_1_3_2_46_2","first-page":"31","article-title":"Analytical techniques to study microbial biofilm on abiotic surfaces: pros and cons of the main techniques currently in use","volume":"25","author":"Pantanella P","year":"2013","unstructured":"Pantanella P, Valenti P, Natalizi T, Passeri D. 2013. Analytical techniques to study microbial biofilm on abiotic surfaces: pros and cons of the main techniques currently in use. Ann Ig 25:31\u201342.","journal-title":"Ann Ig"},{"key":"e_1_3_2_47_2","doi-asserted-by":"publisher","DOI":"10.1088\/0022-3727\/45\/16\/165205"},{"key":"e_1_3_2_48_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0155427"},{"key":"e_1_3_2_49_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1216376110"},{"key":"e_1_3_2_50_2","doi-asserted-by":"publisher","DOI":"10.1128\/AEM.01192-13"},{"key":"e_1_3_2_51_2","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.micro.54.1.49"},{"key":"e_1_3_2_52_2","doi-asserted-by":"publisher","DOI":"10.1128\/CMR.15.2.155-166.2002"},{"key":"e_1_3_2_53_2","doi-asserted-by":"publisher","DOI":"10.1109\/TPS.2012.2204280"},{"key":"e_1_3_2_54_2","doi-asserted-by":"publisher","DOI":"10.1128\/JB.185.5.1485-1491.2003"},{"key":"e_1_3_2_55_2","doi-asserted-by":"publisher","DOI":"10.1083\/jcb.91.3.695"},{"key":"e_1_3_2_56_2","doi-asserted-by":"publisher","DOI":"10.1002\/ctpp.200910067"},{"key":"e_1_3_2_57_2","first-page":"p 429","volume-title":"Mikrobiologische Methoden: eine Einf\u00fchrung in grundlegende Arbeitstechniken","author":"Bast E","year":"2001","unstructured":"Bast E. 2001. Mikrobiologische Methoden: eine Einf\u00fchrung in grundlegende Arbeitstechniken, vol 2, p 429. Elsevier, Amsterdam, Netherlands."},{"key":"e_1_3_2_58_2","volume-title":"Messung beendet\u2014was nun?","author":"Gr\u00e4nicher WHH","year":"1994","unstructured":"Gr\u00e4nicher WHH. 1994. Messung beendet\u2014was nun?, 2:section 6.2.2.\/S6-4-6\u20139. Hochschulverlag AG, Zurich, Switzerland."},{"key":"e_1_3_2_59_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0130350"}],"container-title":["Applied and Environmental Microbiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/AEM.01163-18","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/AEM.01163-18","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,8,30]],"date-time":"2022-08-30T11:33:14Z","timestamp":1661859194000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.asm.org\/doi\/10.1128\/AEM.01163-18"}},"subtitle":[],"editor":[{"given":"Janet L.","family":"Schottel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2018,11]]},"references-count":58,"journal-issue":{"issue":"21","published-print":{"date-parts":[[2018,11]]}},"alternative-id":["10.1128\/AEM.01163-18"],"URL":"https:\/\/doi.org\/10.1128\/aem.01163-18","relation":{},"ISSN":["0099-2240","1098-5336"],"issn-type":[{"value":"0099-2240","type":"print"},{"value":"1098-5336","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,11]]},"assertion":[{"value":"2018-05-15","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2018-08-15","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2018-10-17","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e01163-18"}}