{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T03:46:08Z","timestamp":1790135168025,"version":"4.0.1"},"reference-count":41,"publisher":"American Society for Microbiology","issue":"18","license":[{"start":{"date-parts":[[2012,9,15]],"date-time":"2012-09-15T00:00:00Z","timestamp":1347667200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["Appl Environ Microbiol"],"published-print":{"date-parts":[[2012,9,15]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n          <jats:p>\n            To characterize isolates of\n            <jats:named-content content-type=\"genus-species\">Staphylococcus aureus<\/jats:named-content>\n            that were associated with staphylococcal food poisoning between 2006 and 2009 in Shenzhen, Southern China, a total of 52\n            <jats:named-content content-type=\"genus-species\">Staphylococcus aureus<\/jats:named-content>\n            isolates from 11 outbreaks were analyzed by using multilocus sequence typing (MLST),\n            <jats:italic>spa<\/jats:italic>\n            typing, and pulsed-field gel electrophoresis (PFGE). PCR analysis was used to analyze the staphylococcal enterotoxin (SE) genes\n            <jats:italic>sea<\/jats:italic>\n            to\n            <jats:italic>sei<\/jats:italic>\n            , and antimicrobial susceptibility testing was also performed. ST6 was the most dominant sequence type (ST), constituting 63.5% (34\/52) of all of the isolates in 7 outbreaks. The next most common ST was ST943, which constituted 23.1% (12\/52) of the isolates that were collected from 3 outbreaks. t701, t091, and t2360 were the most predominant\n            <jats:italic>spa<\/jats:italic>\n            types, constituting 67.3% (35\/52) of the isolates that were collected from 11 outbreaks. Three PFGE types, (types A, B, and C) were the most frequently observed types, constituting 84.6% (44\/52) of all of the isolates. The enterotoxin gene that we detected most frequently was\n            <jats:italic>sea<\/jats:italic>\n            (45\/52; 86.5%). Four SE gene profiles were observed, including\n            <jats:italic>sea<\/jats:italic>\n            (\n            <jats:italic>n<\/jats:italic>\n            = 45),\n            <jats:italic>sec-seh<\/jats:italic>\n            (\n            <jats:italic>n<\/jats:italic>\n            = 3),\n            <jats:italic>seb<\/jats:italic>\n            (\n            <jats:italic>n<\/jats:italic>\n            = 2), and\n            <jats:italic>seg-sei<\/jats:italic>\n            (\n            <jats:italic>n<\/jats:italic>\n            = 2). With respect to antibiotic resistance, penicillin resistance was the most common (96.2%; 50\/52), followed by resistance to tetracycline (28.8%; 15\/52). Approximately 30.8% (16\/52) of the isolates were resistant to at least two antibiotics, and 7.7% (4\/52) of the isolates were resistant to three or more drugs. The two predominant\n            <jats:named-content content-type=\"genus-species\">S. aureus<\/jats:named-content>\n            lineages, (i) PFGE types A and B with ST6 and (ii) PFGE type C with ST943, were identified in the outbreaks.\n          <\/jats:p>","DOI":"10.1128\/aem.01165-12","type":"journal-article","created":{"date-parts":[[2012,7,14]],"date-time":"2012-07-14T10:13:06Z","timestamp":1342260786000},"page":"6637-6642","update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":83,"title":["Characterization of Staphylococcus aureus Strains Associated with Food Poisoning in Shenzhen, China"],"prefix":"10.1128","volume":"78","author":[{"given":"Xiaomei","family":"Yan","sequence":"first","affiliation":[{"name":"National Institute for Communicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention\/State Key Laboratory for Infectious Disease Prevention and Control, Beijing, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bing","family":"Wang","sequence":"additional","affiliation":[{"name":"Shenzhen Center for Disease Control and Prevention, Nanshan District, Shenzhen, Guandong Province, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaoxia","family":"Tao","sequence":"additional","affiliation":[{"name":"National Institute for Communicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention\/State Key Laboratory for Infectious Disease Prevention and Control, Beijing, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qinghua","family":"Hu","sequence":"additional","affiliation":[{"name":"Shenzhen Center for Disease Control and Prevention, Nanshan District, Shenzhen, Guandong Province, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhigang","family":"Cui","sequence":"additional","affiliation":[{"name":"National Institute for Communicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention\/State Key Laboratory for Infectious Disease Prevention and Control, Beijing, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jianzhong","family":"Zhang","sequence":"additional","affiliation":[{"name":"National Institute for Communicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention\/State Key Laboratory for Infectious Disease Prevention and Control, Beijing, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yiman","family":"Lin","sequence":"additional","affiliation":[{"name":"Shenzhen Center for Disease Control and Prevention, Nanshan District, Shenzhen, Guandong Province, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuanhai","family":"You","sequence":"additional","affiliation":[{"name":"National Institute for Communicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention\/State Key Laboratory for Infectious Disease Prevention and Control, Beijing, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaolu","family":"Shi","sequence":"additional","affiliation":[{"name":"Shenzhen Center for Disease Control and Prevention, Nanshan District, Shenzhen, Guandong Province, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hajo","family":"Grundmann","sequence":"additional","affiliation":[{"name":"University Medical Centre Groningen, Rijksuniversiteit Groningen, Groningen, Netherlands, and National Institute for Public Health and the Environment (RIVM), Bilthoven, Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"235","reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0168-1605(00)00377-9"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1128\/jcm.30.7.1654-1660.1992"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2672.2006.02957.x"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.1089\/fpd.2007.0088"},{"key":"e_1_3_2_6_2","first-page":"21","article-title":"Detection of toxin genes among Staphylococcus aureus isolates from food-poisoning episodes by PCR assay","volume":"19","author":"Chen Z","year":"2009","unstructured":"ChenZJiangYXiongYZhouSLongY. 2009. 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