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Here, we managed to identify key factors to clarify the virulence of\n            <jats:named-content content-type=\"genus-species\">S. suis<\/jats:named-content>\n            strain CZ130302 from a novel serotype, Chz. Notably, it was shown that a fimbria-like structure was significantly connected to the pathogenicity of the CZ130302 strain by comparative genomics analysis and animal infection assays. The mechanisms of how the CZ130302 strain constructs these fimbria-like structures in the cell surface by genes encoding and production transport were subsequently elucidated. Biosynthesis of the fimbria-like structure was achieved by the production of SssP1 glycoproteins, and its construction was dependent on the SecA2\/Y2 secretion system. This study identified a visible fimbria-like protein, SssP1, participating in adhesion to host cells and contributing to the virulence in\n            <jats:named-content content-type=\"genus-species\">S. suis<\/jats:named-content>\n            . These findings will promote a better understanding of the pathogenesis of\n            <jats:named-content content-type=\"genus-species\">S. suis<\/jats:named-content>\n            .\n          <\/jats:p>","DOI":"10.1128\/aem.01385-18","type":"journal-article","created":{"date-parts":[[2018,7,17]],"date-time":"2018-07-17T11:50:46Z","timestamp":1531828246000},"update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":23,"title":["SssP1, a Streptococcus suis Fimbria-Like Protein Transported by the SecY2\/A2 System, Contributes to Bacterial Virulence"],"prefix":"10.1128","volume":"84","author":[{"given":"Yue","family":"Zhang","sequence":"first","affiliation":[{"name":"College of Veterinary Medicine, Nanjing Agricultural University, Nanjing, China"},{"name":"OIE Reference Lab for Swine Streptococcus suis, Nanjing, China"},{"name":"Key Laboratory of Animal Bacteriology, Ministry of Agriculture, Nanjing, 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