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Despite the pervasiveness of pollution, little is known about the effects of these toxicants on honey bee metabolism and their symbiotic microbiomes. Here, we investigated the impact of selenate and cadmium exposure on the gut microbiome and metabolome of honey bees. We found that exposure to these chemicals subtly altered the overall composition of the bees\u2019 microbiome and metabolome and that exposure to toxicants may negatively impact both host and microbe. As the microbiome of animals can reduce mortality upon metal or metalloid challenge, we grew bee-associated bacteria in media spiked with selenate or cadmium. We show that some bacteria can remove these toxicants from their media\n                    <jats:italic>in vitro<\/jats:italic>\n                    and suggest that bacteria may reduce metal burden in their hosts.\n                  <\/jats:p>","DOI":"10.1128\/aem.01411-19","type":"journal-article","created":{"date-parts":[[2019,8,29]],"date-time":"2019-08-29T05:47:27Z","timestamp":1567057647000},"update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":84,"title":["Cadmium and Selenate Exposure Affects the Honey Bee Microbiome and Metabolome, and Bee-Associated Bacteria Show Potential for Bioaccumulation"],"prefix":"10.1128","volume":"85","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4848-8901","authenticated-orcid":false,"given":"Jason A.","family":"Rothman","sequence":"first","affiliation":[{"name":"Department of Molecular Biology and Biochemistry, University of California, Irvine, Irvine, California, USA"},{"name":"Department of Entomology, University of California, Riverside, Riverside, California, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laura","family":"Leger","sequence":"additional","affiliation":[{"name":"Department of Entomology, University of California, Riverside, Riverside, California, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jay S.","family":"Kirkwood","sequence":"additional","affiliation":[{"name":"Metabolomics Core Facility, Institute for Integrative Genome Biology, University of California, Riverside, Riverside, California, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0740-6954","authenticated-orcid":false,"given":"Quinn S.","family":"McFrederick","sequence":"additional","affiliation":[{"name":"Department of Entomology, University of California, Riverside, Riverside, California, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"235","reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.1098\/rspb.2006.3721"},{"key":"e_1_3_3_3_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1461-0248.2006.00927.x"},{"key":"e_1_3_3_4_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0037235"},{"key":"e_1_3_3_5_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.1255957"},{"key":"e_1_3_3_6_2","doi-asserted-by":"publisher","DOI":"10.1002\/etc.3273"},{"key":"e_1_3_3_7_2","doi-asserted-by":"publisher","DOI":"10.1098\/rsbl.2014.0989"},{"key":"e_1_3_3_8_2","first-page":"137","article-title":"Honey bees as bioindicators of environmental pollution","volume":"56","author":"Celli G","year":"2003","unstructured":"Celli G, Maccagnani B. 2003. 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