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Although metagenomics and bioinformatic studies suggest that natural bacteria remain a source of novel compounds, the identification of genes and their products specific to activity against MDR pathogens remains problematic. Here, we examine water-derived pseudomonads and identify gene clusters whose compounds inhibit CF-derived MDR pathogens, including carbapenem-resistant\n            <jats:named-content content-type=\"genus-species\">P. aeruginosa<\/jats:named-content>\n            .\n          <\/jats:p>","DOI":"10.1128\/aem.01438-19","type":"journal-article","created":{"date-parts":[[2019,9,18]],"date-time":"2019-09-18T09:43:26Z","timestamp":1568799806000},"update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":7,"title":["Loci Encoding Compounds Potentially Active against Drug-Resistant Pathogens amidst a Decreasing Pool of Novel Antibiotics"],"prefix":"10.1128","volume":"85","author":[{"given":"Joseph","family":"Basalla","sequence":"first","affiliation":[{"name":"Department of Biological Sciences, Bowling Green State University, Bowling Green, Ohio, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Payel","family":"Chatterjee","sequence":"additional","affiliation":[{"name":"Department of Biological Sciences, Bowling Green State University, Bowling Green, Ohio, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elizabeth","family":"Burgess","sequence":"additional","affiliation":[{"name":"Department of Biological Sciences, Bowling Green State University, Bowling Green, Ohio, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mahnur","family":"Khan","sequence":"additional","affiliation":[{"name":"Department of Biological Sciences, Bowling Green State University, Bowling Green, Ohio, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emily","family":"Verbrugge","sequence":"additional","affiliation":[{"name":"Department of Biological Sciences, Bowling Green State University, Bowling Green, Ohio, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel D.","family":"Wiegmann","sequence":"additional","affiliation":[{"name":"Department of Biological Sciences, Bowling Green State University, Bowling Green, Ohio, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John J.","family":"LiPuma","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, University of Michigan Medical School, Ann Arbor, Michigan, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hans","family":"Wildschutte","sequence":"additional","affiliation":[{"name":"Department of Biological Sciences, Bowling Green State University, Bowling Green, Ohio, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"235","reference":[{"key":"e_1_3_3_3_2","unstructured":"O\u2019Neill J. 2016. 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