{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,20]],"date-time":"2026-09-20T05:45:57Z","timestamp":1789883157608,"version":"4.0.1"},"reference-count":98,"publisher":"American Society for Microbiology","issue":"5","license":[{"start":{"date-parts":[[2022,3,8]],"date-time":"2022-03-08T00:00:00Z","timestamp":1646697600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/doi.org\/10.1128\/ASMCopyrightv2"},{"start":{"date-parts":[[2022,3,8]],"date-time":"2022-03-08T00:00:00Z","timestamp":1646697600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"funder":[{"name":"Robert Koch Institut"},{"DOI":"10.13039\/501100001659","name":"Deutsche Forschungsgemeinschaft","doi-asserted-by":"publisher","award":["BE5791\/2-1"],"award-info":[{"award-number":["BE5791\/2-1"]}],"id":[{"id":"10.13039\/501100001659","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["Appl Environ Microbiol"],"published-print":{"date-parts":[[2022,3,8]]},"abstract":"<jats:p>\n            To establish infections, Lyme borreliae utilize various means to overcome the host\u2019s immune system. Proteins encoded by the PFam54 gene array play a role in spirochete survival\n            <jats:italic>in vitro<\/jats:italic>\n            and\n            <jats:italic>in vivo<\/jats:italic>\n            .\n          <\/jats:p>","DOI":"10.1128\/aem.01555-21","type":"journal-article","created":{"date-parts":[[2022,1,5]],"date-time":"2022-01-05T21:56:40Z","timestamp":1641419800000},"update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":5,"title":["Utilizing Two Borrelia bavariensis Isolates Naturally Lacking the PFam54 Gene Array To Elucidate the Roles of PFam54-Encoded Proteins"],"prefix":"10.1128","volume":"88","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5779-7001","authenticated-orcid":true,"given":"Robert E.","family":"Rollins","sequence":"first","affiliation":[{"name":"Division of Evolutionary Biology, Faculty of Biology, LMU Munich, Planegg-Martinsried, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Janna","family":"W\u00fclbern","sequence":"additional","affiliation":[{"name":"Division of Evolutionary Biology, Faculty of Biology, LMU Munich, Planegg-Martinsried, Germany"},{"name":"Evolutionary Ecology and Genetics, Faculty of Biology, Christian-Albrechts-Universit\u00e4t zu Kiel, Kiel, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Florian","family":"R\u00f6ttgerding","sequence":"additional","affiliation":[{"name":"Institute of Medical Microbiology and Infection Control, University Hospital Frankfurt, Goethe University Frankfurt, Frankfurt, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tristan A.","family":"Nowak","sequence":"additional","affiliation":[{"name":"Division of Infectious Diseases, Wadsworth Center, New York State Department of Health, Albany, New York, USA"},{"name":"Department of Biomedical Sciences, State University of New York at Albany, Albany, New York, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sabrina","family":"Hepner","sequence":"additional","affiliation":[{"name":"National Reference Centre for Borrelia, Bavarian Health and Food Safety Authority, Oberschleissheim, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Volker","family":"Fingerle","sequence":"additional","affiliation":[{"name":"National Reference Centre for Borrelia, Bavarian Health and Food Safety Authority, Oberschleissheim, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gabriele","family":"Margos","sequence":"additional","affiliation":[{"name":"National Reference Centre for Borrelia, Bavarian Health and Food Safety Authority, Oberschleissheim, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5240-2031","authenticated-orcid":true,"given":"Yi-Pin","family":"Lin","sequence":"additional","affiliation":[{"name":"Division of Infectious Diseases, Wadsworth Center, New York State Department of Health, Albany, New York, USA"},{"name":"Department of Biomedical Sciences, State University of New York at Albany, Albany, New York, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter","family":"Kraiczy","sequence":"additional","affiliation":[{"name":"Institute of Medical Microbiology and Infection Control, University Hospital Frankfurt, Goethe University Frankfurt, Frankfurt, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4968-4103","authenticated-orcid":true,"given":"No\u00e9mie S.","family":"Becker","sequence":"additional","affiliation":[{"name":"Division of Evolutionary Biology, Faculty of Biology, LMU Munich, Planegg-Martinsried, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"235","reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-0691.2010.03175.x"},{"key":"e_1_3_3_3_2","doi-asserted-by":"publisher","DOI":"10.1038\/nrdp.2016.90"},{"key":"e_1_3_3_4_2","doi-asserted-by":"publisher","DOI":"10.2807\/ese.16.27.19906-en"},{"key":"e_1_3_3_5_2","doi-asserted-by":"publisher","DOI":"10.1155\/2012\/595427"},{"key":"e_1_3_3_6_2","doi-asserted-by":"publisher","DOI":"10.15585\/mmwr.ss6622a1"},{"key":"e_1_3_3_7_2","doi-asserted-by":"publisher","DOI":"10.1001\/jamanetworkopen.2020.0328"},{"key":"e_1_3_3_8_2","doi-asserted-by":"publisher","DOI":"10.3201\/eid2702.202731"},{"key":"e_1_3_3_9_2","doi-asserted-by":"publisher","DOI":"10.1038\/nrmicro1475"},{"key":"e_1_3_3_10_2","doi-asserted-by":"publisher","DOI":"10.1038\/nrmicro2714"},{"key":"e_1_3_3_11_2","first-page":"Doc03","article-title":"Guidelines for diagnosis and treatment in neurology: Lyme neuroborreliosis","volume":"18","author":"Rauer S","year":"2020","unstructured":"Rauer S, Kastenbauer S, Hofmann H, Fingerle V, Huppertz H-I, Hunfeld K-P, Krause A, Ruf B, Dersch R, Consensus Group. 2020. Guidelines for diagnosis and treatment in neurology: Lyme neuroborreliosis. Ger Med Sci 18:Doc03.","journal-title":"Ger Med Sci"},{"key":"e_1_3_3_12_2","doi-asserted-by":"publisher","DOI":"10.1051\/parasite\/2008153244"},{"key":"e_1_3_3_13_2","doi-asserted-by":"publisher","DOI":"10.1017\/S0031182003004694"},{"key":"e_1_3_3_14_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41579-020-0400-5"},{"key":"e_1_3_3_15_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF02456135"},{"key":"e_1_3_3_16_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ttbdis.2020.101589"},{"key":"e_1_3_3_17_2","doi-asserted-by":"publisher","DOI":"10.1111\/1462-2920.15100"},{"key":"e_1_3_3_18_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijmm.2007.05.002"},{"key":"e_1_3_3_19_2","doi-asserted-by":"publisher","DOI":"10.1128\/AEM.00116-09"},{"key":"e_1_3_3_20_2","doi-asserted-by":"publisher","DOI":"10.1099\/ijs.0.052001-0"},{"key":"e_1_3_3_21_2","doi-asserted-by":"publisher","DOI":"10.3389\/fevo.2019.00401"},{"key":"e_1_3_3_22_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ttbdis.2021.101766"},{"key":"e_1_3_3_23_2","doi-asserted-by":"publisher","DOI":"10.1186\/s12864-020-07054-3"},{"key":"e_1_3_3_24_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ttbdis.2015.02.008"},{"key":"e_1_3_3_25_2","doi-asserted-by":"publisher","DOI":"10.1186\/s12864-016-3016-4"},{"key":"e_1_3_3_26_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ttbdis.2012.10.039"},{"key":"e_1_3_3_27_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.pt.2020.04.011"},{"key":"e_1_3_3_28_2","doi-asserted-by":"publisher","DOI":"10.21775\/cimb.042.473"},{"key":"e_1_3_3_29_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.tim.2020.05.004"},{"key":"e_1_3_3_30_2","doi-asserted-by":"publisher","DOI":"10.1002\/1873-3468.13894"},{"key":"e_1_3_3_31_2","doi-asserted-by":"publisher","DOI":"10.1016\/B978-0-7020-6896-6.00021-1"},{"key":"e_1_3_3_32_2","doi-asserted-by":"publisher","DOI":"10.1111\/cmi.12786"},{"key":"e_1_3_3_33_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.ppat.1007659"},{"key":"e_1_3_3_34_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.ppat.1005404"},{"key":"e_1_3_3_35_2","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2016.00385"},{"key":"e_1_3_3_36_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.ppat.1008516"},{"key":"e_1_3_3_37_2","doi-asserted-by":"publisher","DOI":"10.1111\/mmi.13239"},{"key":"e_1_3_3_38_2","doi-asserted-by":"publisher","DOI":"10.3389\/fmicb.2011.00141"},{"key":"e_1_3_3_39_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ttbdis.2020.101451"},{"key":"e_1_3_3_40_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.ppat.1007106"},{"key":"e_1_3_3_41_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.gene.2009.05.017"},{"key":"e_1_3_3_42_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0033280"},{"key":"e_1_3_3_43_2","doi-asserted-by":"publisher","DOI":"10.21775\/cimb.042.409"},{"key":"e_1_3_3_44_2","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2180-10-43"},{"key":"e_1_3_3_45_2","doi-asserted-by":"publisher","DOI":"10.1186\/1756-0500-2-134"},{"key":"e_1_3_3_46_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0019536"},{"key":"e_1_3_3_47_2","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.00140-13"},{"key":"e_1_3_3_48_2","doi-asserted-by":"publisher","DOI":"10.1186\/s12864-017-3804-5"},{"key":"e_1_3_3_49_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jmb.2017.12.007"},{"key":"e_1_3_3_50_2","doi-asserted-by":"publisher","DOI":"10.1002\/cpbi.108"},{"key":"e_1_3_3_51_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0197413"},{"key":"e_1_3_3_52_2","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M112.413872"},{"key":"e_1_3_3_53_2","doi-asserted-by":"publisher","DOI":"10.1186\/s12864-018-4597-x"},{"key":"e_1_3_3_54_2","doi-asserted-by":"publisher","DOI":"10.1086\/653825"},{"key":"e_1_3_3_55_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0208432"},{"key":"e_1_3_3_56_2","doi-asserted-by":"publisher","DOI":"10.3389\/fcimb.2020.00001"},{"key":"e_1_3_3_57_2","doi-asserted-by":"publisher","DOI":"10.1128\/iai.56.8.1831-1836.1988"},{"key":"e_1_3_3_58_2","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.71.6.3138-3145.2003"},{"key":"e_1_3_3_59_2","doi-asserted-by":"publisher","DOI":"10.1111\/mmi.12882"},{"key":"e_1_3_3_60_2","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.68.12.6677-6684.2000"},{"key":"e_1_3_3_61_2","doi-asserted-by":"publisher","DOI":"10.1038\/37551"},{"key":"e_1_3_3_62_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2958.2000.01698.x"},{"key":"e_1_3_3_63_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.ppat.1004238"},{"key":"e_1_3_3_64_2","doi-asserted-by":"publisher","DOI":"10.3389\/fmicb.2018.01722"},{"key":"e_1_3_3_65_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41396-021-00939-5"},{"key":"e_1_3_3_66_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00248-019-01442-3"},{"key":"e_1_3_3_67_2","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.01923-06"},{"key":"e_1_3_3_68_2","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.71.8.4432-4440.2003"},{"key":"e_1_3_3_69_2","doi-asserted-by":"publisher","DOI":"10.21775\/cimb.042.223"},{"key":"e_1_3_3_70_2","doi-asserted-by":"publisher","DOI":"10.1128\/mBio.00434-12"},{"key":"e_1_3_3_71_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0022926"},{"key":"e_1_3_3_72_2","doi-asserted-by":"publisher","DOI":"10.1128\/AEM.01567-07"},{"key":"e_1_3_3_73_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0073066"},{"key":"e_1_3_3_74_2","doi-asserted-by":"publisher","DOI":"10.1111\/mmi.14687"},{"key":"e_1_3_3_75_2","doi-asserted-by":"crossref","unstructured":"Margos G Gatewood AG Aanensen DM Hanincov\u00e1 K Terekhova D Vollmer SA Cornet M Piesman J Donaghy M Bormane A Hurn MA Feil EJ Fish D Casjens S Wormser GP Schwartz I Kurtenbach K. 2008. MLST of housekeeping genes captures geographic population structure and suggests a European origin of Borrelia burgdorferi . Proc Natl Acad Sci U S A 105:8730\u20138735. 10.1073\/pnas.0800323105.","DOI":"10.1073\/pnas.0800323105"},{"key":"e_1_3_3_76_2","doi-asserted-by":"publisher","DOI":"10.1007\/82_2017_51"},{"key":"e_1_3_3_77_2","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2164-14-693"},{"key":"e_1_3_3_78_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0176-6724(86)80110-9"},{"key":"e_1_3_3_79_2","doi-asserted-by":"publisher","DOI":"10.1128\/jcm.31.5.1251-1255.1993"},{"key":"e_1_3_3_80_2","doi-asserted-by":"publisher","DOI":"10.1093\/bioinformatics\/btu170"},{"key":"e_1_3_3_81_2","doi-asserted-by":"publisher","DOI":"10.1089\/cmb.2012.0021"},{"key":"e_1_3_3_82_2","doi-asserted-by":"publisher","DOI":"10.1186\/gb-2004-5-2-r12"},{"key":"e_1_3_3_83_2","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/30.11.2478"},{"key":"e_1_3_3_84_2","doi-asserted-by":"publisher","DOI":"10.1093\/bioinformatics\/btv688"},{"key":"e_1_3_3_85_2","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2105-10-421"},{"key":"e_1_3_3_86_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-2836(05)80360-2"},{"key":"e_1_3_3_87_2","doi-asserted-by":"publisher","DOI":"10.1093\/bioinformatics\/17.8.754"},{"key":"e_1_3_3_88_2","doi-asserted-by":"publisher","DOI":"10.1093\/sysbio\/sys029"},{"key":"e_1_3_3_89_2","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.01094-13"},{"key":"e_1_3_3_90_2","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2019.02722"},{"key":"e_1_3_3_91_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0171-2985(00)80094-7"},{"key":"e_1_3_3_92_2","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.69.6.3685-3691.2001"},{"key":"e_1_3_3_93_2","doi-asserted-by":"publisher","DOI":"10.1186\/s13071-021-04959-0"},{"key":"e_1_3_3_94_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ttbdis.2019.101354"},{"key":"e_1_3_3_95_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.ppat.1009801"},{"key":"e_1_3_3_96_2","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.00532-07"},{"key":"e_1_3_3_97_2","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M805844200"},{"key":"e_1_3_3_98_2","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2018.00181"},{"key":"e_1_3_3_99_2","volume-title":"R: a language and environment for statistical computing.","author":"R Core Team","year":"2019","unstructured":"R Core Team. 2019. R: a language and environment for statistical computing. R Foundation for Statistical Computing, Vienna, Austria."}],"container-title":["Applied and Environmental Microbiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/aem.01555-21","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/aem.01555-21","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,3,8]],"date-time":"2022-03-08T16:24:37Z","timestamp":1646756677000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.asm.org\/doi\/10.1128\/aem.01555-21"}},"subtitle":[],"editor":[{"given":"Knut","family":"Rudi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2022,3,8]]},"references-count":98,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2022,3,8]]}},"alternative-id":["10.1128\/aem.01555-21"],"URL":"https:\/\/doi.org\/10.1128\/aem.01555-21","relation":{},"ISSN":["0099-2240","1098-5336"],"issn-type":[{"value":"0099-2240","type":"print"},{"value":"1098-5336","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,3,8]]},"assertion":[{"value":"2021-08-03","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-01-03","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-03-08","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e01555-21"}}