{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T19:21:48Z","timestamp":1790882508594,"version":"4.1.0"},"reference-count":120,"publisher":"American Society for Microbiology","license":[{"start":{"date-parts":[[2024,2,13]],"date-time":"2024-02-13T00:00:00Z","timestamp":1707782400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/doi.org\/10.1128\/ASMCopyrightv2"},{"start":{"date-parts":[[2024,2,13]],"date-time":"2024-02-13T00:00:00Z","timestamp":1707782400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"funder":[{"name":"Government of Canada | Natural Sciences and Engineering Research Council of Canada","award":["NETGP 479720"],"award-info":[{"award-number":["NETGP 479720"]}]}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["Appl Environ Microbiol"],"abstract":"<jats:p>\n            A One Health perspective is crucial to understand the extent of antimicrobial resistance (AMR) globally, and investigation of AMR in the environment has been increasing in recent years. However, most studies have focused on waterways that are directly polluted by sewage, industrial manufacturing, or agricultural activities. Therefore, there remains a lack of knowledge about more natural, less overtly impacted environments. Through phenotypic and genotypic investigation of AMR in\n            <jats:italic>Escherichia coli<\/jats:italic>\n            , this study adds to our understanding of the extent and patterns of resistance in these types of environments, including over a time series, and showed that complex biotic and abiotic factors contribute to the patterns observed. Our study further emphasizes the importance of incorporating the surveillance of microbes in freshwater environments in order to better comprehend potential risks for both human and animal health and how the environment may serve as a sentinel for potential future clinical infections.\n          <\/jats:p>","DOI":"10.1128\/aem.01809-23","type":"journal-article","created":{"date-parts":[[2024,2,13]],"date-time":"2024-02-13T14:01:03Z","timestamp":1707832863000},"update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":11,"title":["Anthropogenic contamination sources drive differences in antimicrobial-resistant\n            <i>Escherichia coli<\/i>\n            in three urban lakes"],"prefix":"10.1128","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7405-0911","authenticated-orcid":false,"given":"Jordan","family":"Wight","sequence":"first","affiliation":[{"name":"Department of Biology, Memorial University of Newfoundland, St. John\u2019s, Newfoundland, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0003-4084-5673","authenticated-orcid":false,"given":"Alexander S.","family":"Byrne","sequence":"additional","affiliation":[{"name":"Department of Biology, Memorial University of Newfoundland, St. John\u2019s, Newfoundland, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2436-682X","authenticated-orcid":false,"given":"Kapil","family":"Tahlan","sequence":"additional","affiliation":[{"name":"Department of Biology, Memorial University of Newfoundland, St. John\u2019s, Newfoundland, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4510-7683","authenticated-orcid":false,"given":"Andrew S.","family":"Lang","sequence":"additional","affiliation":[{"name":"Department of Biology, Memorial University of Newfoundland, St. John\u2019s, Newfoundland, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"235","published-online":{"date-parts":[[2024,2,13]]},"reference":[{"key":"e_1_3_4_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(21)02724-0"},{"key":"e_1_3_4_3_2","first-page":"25","article-title":"Antibiotic resistance of fecal coliform bacteria inhabiting sea water and sand of marine recreation beach in the Southern Baltic sea","volume":"20","author":"Mudryk ZJ","year":"2016","unstructured":"Mudryk ZJ, Perli\u0144ski P, Robak D. 2016. Antibiotic resistance of fecal coliform bacteria inhabiting sea water and sand of marine recreation beach in the Southern Baltic sea. Balt Coast Zone - J Ecol Manag Coastline 20:25\u201336.","journal-title":"Balt Coast Zone - J Ecol Manag Coastline"},{"key":"e_1_3_4_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0043-1354(02)00569-9"},{"key":"e_1_3_4_5_2","doi-asserted-by":"publisher","DOI":"10.1128\/AEM.01880-13"},{"key":"e_1_3_4_6_2","doi-asserted-by":"publisher","DOI":"10.1128\/AEM.02703-16"},{"key":"e_1_3_4_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.watres.2020.115835"},{"key":"e_1_3_4_8_2","doi-asserted-by":"publisher","DOI":"10.1128\/AEM.02980-20"},{"key":"e_1_3_4_9_2","doi-asserted-by":"publisher","DOI":"10.3389\/fmicb.2020.01416"},{"key":"e_1_3_4_10_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-018-25474-w"},{"key":"e_1_3_4_11_2","doi-asserted-by":"publisher","DOI":"10.1080\/10643389.2019.1692611"},{"key":"e_1_3_4_12_2","doi-asserted-by":"publisher","DOI":"10.1146\/annurev-micro-090816-093420"},{"key":"e_1_3_4_13_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.mib.2010.08.005"},{"key":"e_1_3_4_14_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.copbio.2008.05.006"},{"key":"e_1_3_4_15_2","doi-asserted-by":"publisher","DOI":"10.2134\/jeq2010.0253"},{"key":"e_1_3_4_16_2","doi-asserted-by":"publisher","DOI":"10.1089\/mdr.2019.0480"},{"key":"e_1_3_4_17_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.scitotenv.2014.04.100"},{"key":"e_1_3_4_18_2","doi-asserted-by":"publisher","DOI":"10.1038\/nrmicro2298"},{"key":"e_1_3_4_19_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.scitotenv.2021.151937"},{"key":"e_1_3_4_20_2","doi-asserted-by":"publisher","DOI":"10.1186\/s13099-019-0290-0"},{"key":"e_1_3_4_21_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.watres.2013.03.008"},{"key":"e_1_3_4_22_2","doi-asserted-by":"publisher","DOI":"10.1128\/AEM.01445-06"},{"key":"e_1_3_4_23_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijheh.2016.07.015"},{"key":"e_1_3_4_24_2","doi-asserted-by":"publisher","DOI":"10.1101\/gr.216606.116"},{"key":"e_1_3_4_25_2","doi-asserted-by":"publisher","DOI":"10.3201\/eid1402.070350"},{"key":"e_1_3_4_26_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.01118-20"},{"key":"e_1_3_4_27_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.meegid.2020.104265"},{"key":"e_1_3_4_28_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.ppat.1008162"},{"key":"e_1_3_4_30_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejrh.2019.100646"},{"key":"e_1_3_4_31_2","unstructured":"Health Canada. 2009. Categorization of antimicrobial drugs based on importance in human medicine. Available from: https:\/\/www.canada.ca\/en\/health-canada\/services\/drugs-health-products\/veterinary-drugs\/antimicrobial-resistance\/categorization-antimicrobial-drugs-based-importance-human-medicine.html. Retrieved 3 Nov 2022."},{"key":"e_1_3_4_32_2","volume-title":"M100-performance standards for antimicrobial susceptibility testing","author":"CLSI","year":"2018","unstructured":"CLSI. 2018. M100-performance standards for antimicrobial susceptibility testing. 28th ed. Clinical and Laboratory Standards Institute.","edition":"28"},{"key":"e_1_3_4_34_2","doi-asserted-by":"publisher","DOI":"10.1093\/jac\/dkx146"},{"key":"e_1_3_4_35_2","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2180-13-58"},{"key":"e_1_3_4_36_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.01447-16"},{"key":"e_1_3_4_37_2","doi-asserted-by":"publisher","DOI":"10.1111\/lam.13550"},{"key":"e_1_3_4_38_2","doi-asserted-by":"publisher","DOI":"10.1111\/1758-2229.12019"},{"key":"e_1_3_4_39_2","doi-asserted-by":"publisher","DOI":"10.1099\/mgen.0.000192"},{"key":"e_1_3_4_40_2","doi-asserted-by":"publisher","DOI":"10.1128\/AEM.02812-18"},{"key":"e_1_3_4_41_2","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gky379"},{"key":"e_1_3_4_42_2","doi-asserted-by":"publisher","DOI":"10.1093\/bioinformatics\/bty560"},{"key":"e_1_3_4_43_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pcbi.1005595"},{"key":"e_1_3_4_44_2","doi-asserted-by":"publisher","DOI":"10.1186\/s13073-014-0090-6"},{"key":"e_1_3_4_45_2","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkac920"},{"key":"e_1_3_4_46_2","unstructured":"Seemann T. 2022. Abricate: mass screening of contigs for antiobiotic resistance genes. Available from: https:\/\/github.com\/tseemann\/abricate. Retrieved 5 Apr 2023."},{"key":"e_1_3_4_47_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.02412-14"},{"key":"e_1_3_4_48_2","unstructured":"Leimback A. 2016. Ecoli_Vf_Collection: V0.1. doi:https:\/\/zenodo.org\/records\/56686"},{"key":"e_1_3_4_49_2","doi-asserted-by":"publisher","DOI":"10.3390\/microorganisms10020292"},{"key":"e_1_3_4_50_2","doi-asserted-by":"publisher","DOI":"10.1093\/jac\/dkx217"},{"key":"e_1_3_4_51_2","doi-asserted-by":"publisher","DOI":"10.1099\/mgen.0.000206"},{"key":"e_1_3_4_52_2","doi-asserted-by":"publisher","DOI":"10.1093\/bioinformatics\/btx433"},{"key":"e_1_3_4_53_2","doi-asserted-by":"publisher","DOI":"10.3390\/microorganisms10040700"},{"key":"e_1_3_4_54_2","doi-asserted-by":"publisher","DOI":"10.1093\/bioinformatics\/btu153"},{"key":"e_1_3_4_55_2","doi-asserted-by":"publisher","DOI":"10.1093\/bioinformatics\/btv421"},{"key":"e_1_3_4_56_2","doi-asserted-by":"publisher","DOI":"10.1099\/mgen.0.000056"},{"key":"e_1_3_4_57_2","doi-asserted-by":"publisher","DOI":"10.1093\/molbev\/msaa015"},{"key":"e_1_3_4_58_2","doi-asserted-by":"publisher","DOI":"10.1038\/nmeth.4285"},{"key":"e_1_3_4_59_2","doi-asserted-by":"publisher","DOI":"10.1093\/molbev\/msx281"},{"key":"e_1_3_4_60_2","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkab301"},{"key":"e_1_3_4_61_2","volume-title":"Rstudio: integrated development environment for R","author":"RStudio Team","year":"2021","unstructured":"RStudio Team. 2021. Rstudio: integrated development environment for R. RStudio, PBC, Boston, MA."},{"key":"e_1_3_4_62_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.cmi.2017.11.020"},{"key":"e_1_3_4_63_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-0691.2011.03570.x"},{"key":"e_1_3_4_66_2","doi-asserted-by":"publisher","DOI":"10.9778\/cmajo.20200274"},{"key":"e_1_3_4_67_2","doi-asserted-by":"publisher","DOI":"10.1128\/AEM.01682-13"},{"key":"e_1_3_4_68_2","doi-asserted-by":"publisher","DOI":"10.1128\/AEM.02389-14"},{"key":"e_1_3_4_69_2","doi-asserted-by":"publisher","DOI":"10.1139\/w05-028"},{"key":"e_1_3_4_70_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.40.1.237"},{"key":"e_1_3_4_71_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ecolind.2007.06.002"},{"key":"e_1_3_4_72_2","volume-title":"Antibiotics in laboratory medicine","author":"Lorian V","year":"2005","unstructured":"Lorian V. 2005. Antibiotics in laboratory medicine. 5th ed. Lippincott Williams & Wilkins, Philadelphia, PA.","edition":"5"},{"key":"e_1_3_4_73_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.scitotenv.2018.01.343"},{"key":"e_1_3_4_74_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0084048"},{"key":"e_1_3_4_75_2","doi-asserted-by":"publisher","DOI":"10.1099\/mic.0.26486-0"},{"key":"e_1_3_4_76_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0262236"},{"key":"e_1_3_4_77_2","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2180-10-161"},{"key":"e_1_3_4_78_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-020-64544-w"},{"key":"e_1_3_4_79_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.vetmic.2007.08.004"},{"key":"e_1_3_4_80_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.diagmicrobio.2013.02.016"},{"key":"e_1_3_4_81_2","doi-asserted-by":"publisher","DOI":"10.3389\/fmicb.2015.00336"},{"key":"e_1_3_4_82_2","doi-asserted-by":"publisher","DOI":"10.3390\/antibiotics10030237"},{"key":"e_1_3_4_83_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.watres.2013.09.021"},{"key":"e_1_3_4_84_2","doi-asserted-by":"publisher","DOI":"10.1159\/000361011"},{"key":"e_1_3_4_85_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijantimicag.2020.106019"},{"key":"e_1_3_4_86_2","doi-asserted-by":"publisher","DOI":"10.1128\/spectrum.01256-21"},{"key":"e_1_3_4_87_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0020819"},{"key":"e_1_3_4_88_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.watres.2017.07.017"},{"key":"e_1_3_4_89_2","doi-asserted-by":"publisher","DOI":"10.3389\/fmicb.2014.00023"},{"key":"e_1_3_4_90_2","doi-asserted-by":"publisher","DOI":"10.3390\/microbiolres12020026"},{"key":"e_1_3_4_91_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.00451-08"},{"key":"e_1_3_4_92_2","doi-asserted-by":"publisher","DOI":"10.1089\/mdr.2015.0323"},{"key":"e_1_3_4_93_2","doi-asserted-by":"publisher","DOI":"10.1128\/aem.00319-23"},{"key":"e_1_3_4_94_2","doi-asserted-by":"publisher","DOI":"10.1128\/AEM.01913-19"},{"key":"e_1_3_4_95_2","doi-asserted-by":"publisher","DOI":"10.1128\/CMR.00125-13"},{"key":"e_1_3_4_96_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-021-85116-6"},{"key":"e_1_3_4_97_2","doi-asserted-by":"publisher","DOI":"10.1128\/mBio.00644-19"},{"key":"e_1_3_4_98_2","doi-asserted-by":"publisher","DOI":"10.1099\/mic.0.27499-0"},{"key":"e_1_3_4_99_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.00179-17"},{"key":"e_1_3_4_100_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jgar.2021.12.018"},{"key":"e_1_3_4_101_2","doi-asserted-by":"publisher","DOI":"10.1186\/s12941-022-00521-7"},{"key":"e_1_3_4_102_2","doi-asserted-by":"publisher","DOI":"10.3390\/pathogens11070776"},{"key":"e_1_3_4_103_2","doi-asserted-by":"publisher","DOI":"10.1098\/rspb.2020.1680"},{"key":"e_1_3_4_104_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1462-2920.2011.02519.x"},{"key":"e_1_3_4_105_2","doi-asserted-by":"publisher","DOI":"10.1264\/jsme2.23.101"},{"key":"e_1_3_4_106_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1015622108"},{"key":"e_1_3_4_107_2","doi-asserted-by":"publisher","DOI":"10.1128\/ecosalplus.ESP-0002-2015"},{"key":"e_1_3_4_108_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.watres.2019.03.024"},{"key":"e_1_3_4_109_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1462-2920.2007.01341.x"},{"key":"e_1_3_4_110_2","doi-asserted-by":"publisher","DOI":"10.1128\/AEM.01978-18"},{"key":"e_1_3_4_111_2","doi-asserted-by":"publisher","DOI":"10.1128\/AEM.72.1.612-621.2006"},{"key":"e_1_3_4_112_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-019-54004-5"},{"key":"e_1_3_4_113_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.scitotenv.2020.144551"},{"key":"e_1_3_4_114_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.scitotenv.2022.153632"},{"key":"e_1_3_4_115_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.scitotenv.2017.09.232"},{"key":"e_1_3_4_116_2","doi-asserted-by":"publisher","DOI":"10.1111\/1462-2920.13874"},{"key":"e_1_3_4_117_2","doi-asserted-by":"publisher","DOI":"10.3389\/fmicb.2021.703886"},{"key":"e_1_3_4_118_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-020-61318-2"},{"key":"e_1_3_4_119_2","doi-asserted-by":"publisher","DOI":"10.1128\/AEM.00949-08"},{"key":"e_1_3_4_120_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0005958"},{"key":"e_1_3_4_121_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.scitotenv.2020.143699"},{"key":"e_1_3_4_122_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.tim.2006.02.006"},{"key":"e_1_3_4_123_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0027300"},{"key":"e_1_3_4_124_2","doi-asserted-by":"publisher","DOI":"10.3389\/fpubh.2021.726484"},{"key":"e_1_3_4_125_2","doi-asserted-by":"publisher","DOI":"10.1186\/s12864-015-2153-5"}],"container-title":["Applied and Environmental Microbiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/aem.01809-23","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/aem.01809-23","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,3,17]],"date-time":"2024-03-17T17:19:57Z","timestamp":1710695997000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.asm.org\/doi\/10.1128\/aem.01809-23"}},"subtitle":[],"editor":[{"given":"Christopher A.","family":"Elkins","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2024,2,13]]},"references-count":120,"alternative-id":["10.1128\/aem.01809-23"],"URL":"https:\/\/doi.org\/10.1128\/aem.01809-23","relation":{},"ISSN":["0099-2240","1098-5336"],"issn-type":[{"value":"0099-2240","type":"print"},{"value":"1098-5336","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,2,13]]},"assertion":[{"value":"2023-10-13","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-01-12","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-02-13","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e01809-23"}}