{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T18:10:02Z","timestamp":1791223802290,"version":"4.1.0"},"reference-count":48,"publisher":"American Society for Microbiology","issue":"16","license":[{"start":{"date-parts":[[2011,8,15]],"date-time":"2011-08-15T00:00:00Z","timestamp":1313366400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["Appl Environ Microbiol"],"published-print":{"date-parts":[[2011,8,15]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:p>Little attention has been given in scientific literature to how introduced species may act as a new host for native infectious agents and modify the epidemiology of a disease. In this study, we investigated whether an introduced species, the Siberian chipmunk (<jats:named-content content-type=\"genus-species\">Tamias sibiricus barberi<\/jats:named-content>), was a potentially new reservoir host for<jats:named-content content-type=\"genus-species\">Borrelia burgdorferi<\/jats:named-content>sensu lato, the causative agent of Lyme disease. First, we ascertained whether chipmunks were infected by all of the<jats:named-content content-type=\"genus-species\">B. burgdorferi<\/jats:named-content>sensu lato genospecies associated with rodents and available in their source of infection, questing nymphs. Second, we determined whether the prevalence and diversity of<jats:named-content content-type=\"genus-species\">B. burgdorferi<\/jats:named-content>sensu lato in chipmunks were similar to those of a native reservoir rodent, the bank vole (<jats:named-content content-type=\"genus-species\">Myodes glareolus<\/jats:named-content>). Our research took place between 2006 and 2008 in a suburban French forest, where we trapped 335 chipmunks and 671 voles and collected 743 nymphs of ticks that were questing for hosts by dragging on the vegetation. We assayed for<jats:named-content content-type=\"genus-species\">B. burgdorferi<\/jats:named-content>sensu lato with ear biopsy specimens taken from the rodents and in nymphs using PCR and restriction fragment length polymorphism (RFLP). Chipmunks were infected by the three<jats:named-content content-type=\"genus-species\">Borrelia<\/jats:named-content>genospecies that were present in questing nymphs and that infect rodents (<jats:named-content content-type=\"genus-species\">B. burgdorferi<\/jats:named-content>sensu stricto,<jats:named-content content-type=\"genus-species\">B. afzelii<\/jats:named-content>, and<jats:named-content content-type=\"genus-species\">B. garinii<\/jats:named-content>). In contrast, voles hosted only<jats:named-content content-type=\"genus-species\">B. afzelii<\/jats:named-content>. Furthermore, chipmunks were more infected (35%) than voles (16%). These results may be explained by the higher exposure of chipmunks, because they harbor more ticks, or by their higher tolerance of other<jats:named-content content-type=\"genus-species\">B. burgdorferi<\/jats:named-content>sensu lato genospecies than of<jats:named-content content-type=\"genus-species\">B. afzelii<\/jats:named-content>. If chipmunks are competent reservoir hosts for<jats:named-content content-type=\"genus-species\">B. burgdorferi<\/jats:named-content>sensu lato, they may spill back<jats:named-content content-type=\"genus-species\">B. burgdorferi<\/jats:named-content>sensu lato to native communities and eventually may increase the risk of Lyme disease transmission to humans.<\/jats:p>","DOI":"10.1128\/aem.01846-10","type":"journal-article","created":{"date-parts":[[2011,6,25]],"date-time":"2011-06-25T23:16:27Z","timestamp":1309043787000},"page":"5716-5721","update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":46,"title":["Introduced Siberian Chipmunks (Tamias sibiricus barberi) Harbor More-Diverse Borrelia burgdorferi Sensu Lato Genospecies than Native Bank Voles (Myodes glareolus)"],"prefix":"10.1128","volume":"77","author":[{"given":"M.","family":"Marsot","sequence":"first","affiliation":[{"name":"Institut National de la Recherche Agronomique, UR 346 Epid\u00e9miologie Animale, 63122 Saint Gen\u00e8s Champanelle, France"},{"name":"Mus\u00e9um National d'Histoire Naturelle, D\u00e9partement Ecologie et Gestion de la Biodiversit\u00e9, UMR 7204 CERSP MNHN-CNRS-P6, 61 Rue Buffon, CP 53, 75231 Paris Cedex 05, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Sigaud","sequence":"additional","affiliation":[{"name":"Institut Pasteur, Centre National de R\u00e9f\u00e9rence des Borrelia, 25-28 Rue du Docteur Roux, 75724 Paris Cedex 15, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J. L.","family":"Chapuis","sequence":"additional","affiliation":[{"name":"Mus\u00e9um National d'Histoire Naturelle, D\u00e9partement Ecologie et Gestion de la Biodiversit\u00e9, UMR 7204 CERSP MNHN-CNRS-P6, 61 Rue Buffon, CP 53, 75231 Paris Cedex 05, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"E.","family":"Ferquel","sequence":"additional","affiliation":[{"name":"Institut Pasteur, Centre National de R\u00e9f\u00e9rence des Borrelia, 25-28 Rue du Docteur Roux, 75724 Paris Cedex 15, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Cornet","sequence":"additional","affiliation":[{"name":"Institut Pasteur, Centre National de R\u00e9f\u00e9rence des Borrelia, 25-28 Rue du Docteur Roux, 75724 Paris Cedex 15, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G.","family":"Vourc'h","sequence":"additional","affiliation":[{"name":"Institut National de la Recherche Agronomique, UR 346 Epid\u00e9miologie Animale, 63122 Saint Gen\u00e8s Champanelle, France"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"235","reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"crossref","DOI":"10.1093\/oso\/9780198524137.001.0001","volume-title":"Statistical modelling in GLIM","author":"Aitkin M. 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