{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T00:31:16Z","timestamp":1792024276238,"version":"4.4.0"},"reference-count":44,"publisher":"American Society for Microbiology","issue":"2","license":[{"start":{"date-parts":[[2021,1,4]],"date-time":"2021-01-04T00:00:00Z","timestamp":1609718400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["Appl Environ Microbiol"],"published-print":{"date-parts":[[2021,1,4]]},"abstract":"<jats:p>\n                    Some microbes utilize different dissimilatory nitrate reduction (DNR) pathways, including DNR to ammonia (DNRA) and denitrification pathways, for anaerobic respiration in response to ambient carbon\/nitrogen ratio changes. Large-scale industrial nitrogen fixation and fertilizer application raise the concern of emission of N\n                    <jats:sub>2<\/jats:sub>\n                    O, a stable gas with potent global warming potential, as consequence of microbial respiration, thereby aggravating global warming and climate change. However, little is known about the molecular mechanism underlying the choice of two competing DNR pathways. We demonstrate that the global regulator CRP1, which is widely encoded in bacteria, is required for DNRA in\n                    <jats:named-content content-type=\"genus-species\">S. loihica<\/jats:named-content>\n                    PV-4 strain, while the CRP2 paralogue is required for transcription of the nitrite reductase gene\n                    <jats:italic>nirK<\/jats:italic>\n                    for denitrification. Sufficient carbon source lead to the predominance of DNRA, while carbon source\/electron donor deficiency may result in an incomplete denitrification process, raising the concern of high levels of N\n                    <jats:sub>2<\/jats:sub>\n                    O emission from nitrate-rich and carbon source-poor waters and soils.\n                  <\/jats:p>","DOI":"10.1128\/aem.01964-20","type":"journal-article","created":{"date-parts":[[2020,11,4]],"date-time":"2020-11-04T09:24:36Z","timestamp":1604481876000},"update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":78,"title":["Dissimilatory Nitrate Reduction to Ammonium (DNRA) and Denitrification Pathways Are Leveraged by Cyclic AMP Receptor Protein (CRP) Paralogues Based on Electron Donor\/Acceptor Limitation in Shewanella loihica PV-4"],"prefix":"10.1128","volume":"87","author":[{"given":"Shuangyuan","family":"Liu","sequence":"first","affiliation":[{"name":"Institute of Hydrobiology, Chinese Academy of Sciences, Wuhan, China"},{"name":"University of Chinese Academy of Sciences, Beijing, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jingcheng","family":"Dai","sequence":"additional","affiliation":[{"name":"Institute of Hydrobiology, Chinese Academy of Sciences, Wuhan, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hehong","family":"Wei","sequence":"additional","affiliation":[{"name":"Institute of Hydrobiology, Chinese Academy of Sciences, Wuhan, China"},{"name":"College of Energy and Environmental Engineering, Hebei University of Engineering, Handan, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shuyang","family":"Li","sequence":"additional","affiliation":[{"name":"Institute of Hydrobiology, Chinese Academy of Sciences, Wuhan, China"},{"name":"University of Chinese Academy of Sciences, Beijing, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pei","family":"Wang","sequence":"additional","affiliation":[{"name":"Institute of Hydrobiology, Chinese Academy of Sciences, Wuhan, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tongbin","family":"Zhu","sequence":"additional","affiliation":[{"name":"Institute of Karst Geology, Chinese Academy of Geological Sciences, Guilin, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jizhong","family":"Zhou","sequence":"additional","affiliation":[{"name":"Institute for Environmental Genomics and Department of Plant Biology and Microbiology, University of Oklahoma, Norman, Oklahoma, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5344-6493","authenticated-orcid":false,"given":"Dongru","family":"Qiu","sequence":"additional","affiliation":[{"name":"Institute of Hydrobiology, Chinese Academy of Sciences, Wuhan, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"235","reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.scitotenv.2017.01.127"},{"key":"e_1_3_3_3_2","doi-asserted-by":"publisher","DOI":"10.1039\/c3cs60249d"},{"key":"e_1_3_3_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1367-5931(99)80034-9"},{"key":"e_1_3_3_5_2","doi-asserted-by":"publisher","DOI":"10.1128\/.61.4.533-616.1997"},{"key":"e_1_3_3_6_2","doi-asserted-by":"publisher","DOI":"10.1128\/AEM.02508-06"},{"key":"e_1_3_3_7_2","doi-asserted-by":"publisher","DOI":"10.1128\/AEM.00688-15"},{"key":"e_1_3_3_8_2","doi-asserted-by":"publisher","DOI":"10.1038\/ismej.2014.201"},{"key":"e_1_3_3_9_2","doi-asserted-by":"publisher","DOI":"10.3389\/fmicb.2017.01820"},{"key":"e_1_3_3_10_2","doi-asserted-by":"publisher","DOI":"10.1128\/AEM.00619-13"},{"key":"e_1_3_3_11_2","doi-asserted-by":"publisher","DOI":"10.1038\/ismej.2010.182"},{"key":"e_1_3_3_12_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0051643"},{"key":"e_1_3_3_13_2","doi-asserted-by":"publisher","DOI":"10.1099\/mic.0.034421-0"},{"key":"e_1_3_3_14_2","doi-asserted-by":"publisher","DOI":"10.1128\/jb.185.12.3668-3671.2003"},{"key":"e_1_3_3_15_2","doi-asserted-by":"publisher","DOI":"10.1128\/AEM.00203-16"},{"key":"e_1_3_3_16_2","doi-asserted-by":"publisher","DOI":"10.1128\/JB.01194-06"},{"key":"e_1_3_3_17_2","doi-asserted-by":"publisher","DOI":"10.1038\/ismej.2009.40"},{"key":"e_1_3_3_18_2","doi-asserted-by":"publisher","DOI":"10.1099\/mic.0.000285"},{"key":"e_1_3_3_19_2","doi-asserted-by":"publisher","DOI":"10.1128\/JB.00873-08"},{"key":"e_1_3_3_20_2","doi-asserted-by":"publisher","DOI":"10.1128\/JB.01829-08"},{"key":"e_1_3_3_21_2","doi-asserted-by":"publisher","DOI":"10.1128\/JB.01293-08"},{"key":"e_1_3_3_22_2","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkh908"},{"key":"e_1_3_3_23_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0015295"},{"key":"e_1_3_3_24_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2958.1997.4971855.x"},{"key":"e_1_3_3_25_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.89.18.8419"},{"key":"e_1_3_3_26_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2958.1992.tb01364.x"},{"key":"e_1_3_3_27_2","doi-asserted-by":"publisher","DOI":"10.1099\/ijs.0.64354-0"},{"key":"e_1_3_3_28_2","doi-asserted-by":"publisher","DOI":"10.1128\/jb.172.11.6232-6238.1990"},{"key":"e_1_3_3_29_2","doi-asserted-by":"publisher","DOI":"10.1128\/AEM.03872-12"},{"key":"e_1_3_3_30_2","doi-asserted-by":"publisher","DOI":"10.1128\/JB.186.24.8385-8400.2004"},{"key":"e_1_3_3_31_2","volume-title":"Wastewater monitoring methods","author":"Ministry of Environmental Protection of the People\u2019s Republic of China","year":"2002","unstructured":"Ministry of Environmental Protection of the People\u2019s Republic of China. 2002. Wastewater monitoring methods. Chinese Environmental Science Publishing House, Beijing, China. (In Chinese.)"},{"key":"e_1_3_3_32_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.scitotenv.2017.11.192"},{"key":"e_1_3_3_33_2","doi-asserted-by":"publisher","DOI":"10.1038\/ismej.2011.63"},{"key":"e_1_3_3_34_2","doi-asserted-by":"publisher","DOI":"10.1021\/es3017446"},{"key":"e_1_3_3_35_2","doi-asserted-by":"publisher","DOI":"10.1021\/es202183w"},{"key":"e_1_3_3_36_2","doi-asserted-by":"publisher","DOI":"10.1038\/ngeo1683"},{"key":"e_1_3_3_37_2","doi-asserted-by":"publisher","DOI":"10.1038\/ismej.2015.25"},{"key":"e_1_3_3_38_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00253-010-2451-4"},{"key":"e_1_3_3_39_2","doi-asserted-by":"publisher","DOI":"10.1128\/aem.68.3.1312-1318.2002"},{"key":"e_1_3_3_40_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41396-018-0316-5"},{"key":"e_1_3_3_41_2","doi-asserted-by":"publisher","DOI":"10.1006\/meth.2001.1262"},{"key":"e_1_3_3_42_2","doi-asserted-by":"publisher","DOI":"10.1038\/nprot.2008.73"},{"key":"e_1_3_3_43_2","doi-asserted-by":"publisher","DOI":"10.1186\/s12866-015-0357-0"},{"key":"e_1_3_3_44_2","doi-asserted-by":"publisher","DOI":"10.3389\/fmicb.2017.01714"},{"key":"e_1_3_3_45_2","doi-asserted-by":"publisher","DOI":"10.1128\/AEM.01369-08"}],"container-title":["Applied and Environmental Microbiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/AEM.01964-20","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/AEM.01964-20","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,2,23]],"date-time":"2022-02-23T14:16:58Z","timestamp":1645625818000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.asm.org\/doi\/10.1128\/AEM.01964-20"}},"subtitle":[],"editor":[{"given":"Haruyuki","family":"Atomi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2021,1,4]]},"references-count":44,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2021,1,4]]}},"alternative-id":["10.1128\/AEM.01964-20"],"URL":"https:\/\/doi.org\/10.1128\/aem.01964-20","relation":{},"ISSN":["0099-2240","1098-5336"],"issn-type":[{"value":"0099-2240","type":"print"},{"value":"1098-5336","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,1,4]]},"assertion":[{"value":"2020-08-11","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-10-29","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-01-04","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e01964-20"}}