{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T01:32:57Z","timestamp":1787016777058,"version":"build-2736575974"},"reference-count":32,"publisher":"American Society for Microbiology","issue":"8","license":[{"start":{"date-parts":[[2019,4,15]],"date-time":"2019-04-15T00:00:00Z","timestamp":1555286400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"funder":[{"name":"The project of state key laboratory of freshwater ecology and biotechnology","award":["2016FBZ04"],"award-info":[{"award-number":["2016FBZ04"]}]},{"name":"China Agriculture Research System","award":["CARS-46"],"award-info":[{"award-number":["CARS-46"]}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["31572659"],"award-info":[{"award-number":["31572659"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["Appl Environ Microbiol"],"published-print":{"date-parts":[[2019,4,15]]},"abstract":"<jats:p>\n                    <jats:named-content content-type=\"genus-species\">Edwardsiella piscicida<\/jats:named-content>\n                    , previously known as\n                    <jats:named-content content-type=\"genus-species\">Edwardsiella tarda<\/jats:named-content>\n                    , is a Gram-negative intracellular pathogen that mainly infects fish. The type III secretion system (T3SS) plays a pivotal role in its pathogenesis. The T3SS translocon protein EseB is required for the assembly of filamentous appendages on the surface of\n                    <jats:named-content content-type=\"genus-species\">E. piscicida<\/jats:named-content>\n                    . The interactions between the appendages facilitate autoaggregation and biofilm formation. In this study, we explored the role of the other two translocon proteins, EseC and EseD, in biofilm formation. We have demonstrated that EseC, but not EseD, inhibits the autoaggregation and biofilm formation of\n                    <jats:named-content content-type=\"genus-species\">E. piscicida<\/jats:named-content>\n                    , providing new insights into the regulatory mechanism involved in\n                    <jats:named-content content-type=\"genus-species\">E. piscicida<\/jats:named-content>\n                    biofilm formation.\n                  <\/jats:p>","DOI":"10.1128\/aem.02133-18","type":"journal-article","created":{"date-parts":[[2019,2,14]],"date-time":"2019-02-14T08:25:23Z","timestamp":1550132723000},"update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":14,"title":["The\n                    <i>Edwardsiella piscicida<\/i>\n                    Type III Translocon Protein EseC Inhibits Biofilm Formation by Sequestering EseE"],"prefix":"10.1128","volume":"85","author":[{"given":"Ying Li","family":"Liu","sequence":"first","affiliation":[{"name":"State Key Laboratory of Freshwater Ecology and Biotechnology, and Key Laboratory of Aquaculture Disease Control, Ministry of Agriculture, Institute of Hydrobiology, Chinese Academy of Sciences, Wuhan, Hubei, China"},{"name":"University of Chinese Academy of Sciences, Beijing, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tian Tian","family":"He","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Freshwater Ecology and Biotechnology, and Key Laboratory of Aquaculture Disease Control, Ministry of Agriculture, Institute of Hydrobiology, Chinese Academy of Sciences, Wuhan, Hubei, China"},{"name":"University of Chinese Academy of Sciences, Beijing, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lu Yi","family":"Liu","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Freshwater Ecology and Biotechnology, and Key Laboratory of Aquaculture Disease Control, Ministry of Agriculture, Institute of Hydrobiology, Chinese Academy of Sciences, Wuhan, Hubei, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jia","family":"Yi","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Freshwater Ecology and Biotechnology, and Key Laboratory of Aquaculture Disease Control, Ministry of Agriculture, Institute of Hydrobiology, Chinese Academy of Sciences, Wuhan, Hubei, China"},{"name":"University of Chinese Academy of Sciences, Beijing, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pin","family":"Nie","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Freshwater Ecology and Biotechnology, and Key Laboratory of Aquaculture Disease Control, Ministry of Agriculture, Institute of Hydrobiology, Chinese Academy of Sciences, Wuhan, Hubei, China"},{"name":"Laboratory for Marine Biology and Biotechnology, Qingdao National Laboratory for Marine Science and 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