{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T01:30:03Z","timestamp":1787016603289,"version":"build-2736575974"},"reference-count":77,"publisher":"American Society for Microbiology","issue":"2","license":[{"start":{"date-parts":[[2021,1,4]],"date-time":"2021-01-04T00:00:00Z","timestamp":1609718400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"funder":[{"name":"Rainwater Foundation"},{"DOI":"10.13039\/100000002","name":"HHS | National Institutes of Health","doi-asserted-by":"publisher","award":["R01 AI 130105"],"award-info":[{"award-number":["R01 AI 130105"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["Appl Environ Microbiol"],"published-print":{"date-parts":[[2021,1,4]]},"abstract":"<jats:p>White-footed mice are thought to be the most important reservoir host for the deer tick-transmitted pathogens that cause Lyme disease and human babesiosis because they are the primary host for immature ticks. Transmission would be reduced, however, if ticks feed on deer, which are not capable of infecting ticks with either pathogen. By directly measuring whether ticks had fed on either mice or deer using a new quantitative PCR (qPCR) assay to detect remnants of host DNA leftover from the larval blood meal, we demonstrate that host utilization by ticks varies significantly over time and space and that mice often feed fewer ticks than expected. This finding has implications for our understanding of the ecology of these diseases and for the efficacy of control measures.<\/jats:p>","DOI":"10.1128\/aem.02370-20","type":"journal-article","created":{"date-parts":[[2020,11,5]],"date-time":"2020-11-05T09:28:12Z","timestamp":1604568492000},"update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":31,"title":["Retrotransposon-Based Blood Meal Analysis of Nymphal Deer Ticks Demonstrates Spatiotemporal Diversity of Borrelia burgdorferi and Babesia microti Reservoirs"],"prefix":"10.1128","volume":"87","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5145-9047","authenticated-orcid":false,"given":"Heidi K.","family":"Goethert","sequence":"first","affiliation":[{"name":"Department of Infectious Disease and Global Health, Tufts University, North Grafton, Massachusetts, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas N.","family":"Mather","sequence":"additional","affiliation":[{"name":"University of Rhode Island, Center for Vector Borne Disease, Kingston, Rhode Island, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joanna","family":"Buchthal","sequence":"additional","affiliation":[{"name":"Media Lab, Massachusetts Institute of Technology, Cambridge, Massachusetts, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"suffix":"III","given":"Sam R.","family":"Telford","sequence":"additional","affiliation":[{"name":"Department of Infectious Disease and Global Health, Tufts University, North Grafton, Massachusetts, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"235","reference":[{"key":"e_1_3_4_2_2","doi-asserted-by":"publisher","DOI":"10.1002\/art.1780200102"},{"key":"e_1_3_4_3_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM197010152831607"},{"key":"e_1_3_4_4_2","doi-asserted-by":"publisher","DOI":"10.15585\/mmwr.mm6717e1"},{"key":"e_1_3_4_5_2","unstructured":"Centers for Disease Control and Prevention. 2018. Nationally notifiable infectious diseases and conditions United States: annual tables. https:\/\/wonder.cdc.gov\/nndss\/nndss_annual_tables_menu.asp."},{"key":"e_1_3_4_6_2","doi-asserted-by":"publisher","DOI":"10.15585\/mmwr.ss6622a1"},{"key":"e_1_3_4_7_2","doi-asserted-by":"publisher","DOI":"10.1080\/21548331.1979.11707564"},{"key":"e_1_3_4_8_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.769166"},{"key":"e_1_3_4_9_2","doi-asserted-by":"publisher","DOI":"10.4269\/ajtmh.1985.34.355"},{"key":"e_1_3_4_10_2","doi-asserted-by":"publisher","DOI":"10.1093\/jmedent\/19.6.655"},{"key":"e_1_3_4_11_2","doi-asserted-by":"publisher","DOI":"10.1093\/oxfordjournals.aje.a115306"},{"key":"e_1_3_4_12_2","doi-asserted-by":"publisher","DOI":"10.4269\/ajtmh.1981.30.560"},{"key":"e_1_3_4_13_2","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.25.8.1564-1566.1987"},{"key":"e_1_3_4_14_2","doi-asserted-by":"publisher","DOI":"10.1016\/0020-7519(88)90105-1"},{"key":"e_1_3_4_15_2","doi-asserted-by":"publisher","DOI":"10.1016\/0014-4894(90)90085-Q"},{"key":"e_1_3_4_16_2","doi-asserted-by":"publisher","DOI":"10.1016\/0014-4894(82)90065-0"},{"key":"e_1_3_4_17_2","doi-asserted-by":"publisher","DOI":"10.1093\/clinids\/11.Supplement_6.S1451"},{"key":"e_1_3_4_18_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0233733100"},{"key":"e_1_3_4_19_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1749-6632.1988.tb31855.x"},{"key":"e_1_3_4_20_2","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.en.30.010185.002255"},{"key":"e_1_3_4_21_2","doi-asserted-by":"publisher","DOI":"10.1890\/0012-9658(2001)082[0609:BATDEI]2.0.CO;2"},{"key":"e_1_3_4_22_2","first-page":"473","article-title":"Identification of blood meals of blood-sucking arthropods","volume":"15","author":"Weitz B","year":"1956","unstructured":"Weitz B. 1956. Identification of blood meals of blood-sucking arthropods. Bull World Health Organ 15:473\u2013490.","journal-title":"Bull World Health Organ"},{"key":"e_1_3_4_23_2","doi-asserted-by":"publisher","DOI":"10.4269\/ajtmh.1981.30.1336"},{"key":"e_1_3_4_24_2","unstructured":"Balashov YS. 1968. Bloodsucking ticks ( Ixodoidea )\u2014vectors of disease in man and animals. Nauka Moscow Russia."},{"key":"e_1_3_4_25_2","doi-asserted-by":"publisher","DOI":"10.1603\/0022-2585(2007)44[1109:IOHBSA]2.0.CO;2"},{"key":"e_1_3_4_26_2","doi-asserted-by":"publisher","DOI":"10.1186\/s13071-016-1901-y"},{"key":"e_1_3_4_27_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.vetpar.2015.04.007"},{"key":"e_1_3_4_28_2","doi-asserted-by":"publisher","DOI":"10.1007\/s10493-005-3271-6"},{"key":"e_1_3_4_29_2","doi-asserted-by":"publisher","DOI":"10.1093\/femsec\/fix129"},{"key":"e_1_3_4_30_2","doi-asserted-by":"publisher","DOI":"10.1603\/0022-2585(2007)44[869:MIOBSI]2.0.CO;2"},{"key":"e_1_3_4_31_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0934-8840(99)80052-8"},{"key":"e_1_3_4_32_2","doi-asserted-by":"publisher","DOI":"10.1603\/0022-2585-40.5.723"},{"key":"e_1_3_4_33_2","doi-asserted-by":"publisher","DOI":"10.1007\/s10493-013-9763-x"},{"key":"e_1_3_4_34_2","doi-asserted-by":"publisher","DOI":"10.5604\/12321966.1196853"},{"key":"e_1_3_4_35_2","doi-asserted-by":"publisher","DOI":"10.1111\/mve.12372"},{"key":"e_1_3_4_36_2","doi-asserted-by":"publisher","DOI":"10.1038\/ncomms2730"},{"key":"e_1_3_4_37_2","doi-asserted-by":"publisher","DOI":"10.1128\/microbiolspec.MDNA3-0061-2014"},{"key":"e_1_3_4_38_2","doi-asserted-by":"crossref","first-page":"310","DOI":"10.1093\/oso\/9780195150933.003.0024","volume-title":"Conservation medicine: ecological health in practice","author":"Telford SR","year":"2002","unstructured":"Telford SR, III. 2002. Deer tick transmitted zoonoses in the eastern United States, p 310\u2013324. In Conservation medicine: ecological health in practice. Oxford University Press, New York, NY."},{"key":"e_1_3_4_39_2","doi-asserted-by":"publisher","DOI":"10.1093\/jmedent\/25.4.224"},{"key":"e_1_3_4_40_2","doi-asserted-by":"publisher","DOI":"10.3201\/eid1812.111392"},{"key":"e_1_3_4_41_2","doi-asserted-by":"publisher","DOI":"10.4269\/ajtmh.1988.39.105"},{"key":"e_1_3_4_42_2","doi-asserted-by":"publisher","DOI":"10.1093\/aesa\/72.6.829"},{"key":"e_1_3_4_43_2","doi-asserted-by":"publisher","DOI":"10.3201\/eid0302.970209"},{"key":"e_1_3_4_44_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.93.12.6209"},{"key":"e_1_3_4_45_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1749-6632.1988.tb31852.x"},{"key":"e_1_3_4_46_2","doi-asserted-by":"publisher","DOI":"10.1093\/jmedent\/30.4.740"},{"key":"e_1_3_4_47_2","doi-asserted-by":"publisher","DOI":"10.7589\/0090-3558-33.1.40"},{"key":"e_1_3_4_48_2","doi-asserted-by":"publisher","DOI":"10.4269\/ajtmh.1987.36.92"},{"key":"e_1_3_4_49_2","first-page":"147","volume-title":"The biology of parasitism","author":"Spielman A","year":"1988","unstructured":"Spielman A. 1988. Lyme disease and human babesiosis: evidence incriminating vector and reservoir hosts, p 147\u2013165. In Englund PT, Sher A (ed), The biology of parasitism. Alan R. Liss, New York, NY."},{"key":"e_1_3_4_50_2","doi-asserted-by":"publisher","DOI":"10.4269\/ajtmh.2011.11-0292"},{"key":"e_1_3_4_51_2","doi-asserted-by":"publisher","DOI":"10.4269\/ajtmh.1987.36.609"},{"key":"e_1_3_4_52_2","doi-asserted-by":"publisher","DOI":"10.1093\/jmedent\/28.4.537"},{"key":"e_1_3_4_53_2","doi-asserted-by":"publisher","DOI":"10.1603\/0022-2585-41.6.1043"},{"key":"e_1_3_4_54_2","first-page":"91","article-title":"Effectiveness of Metarhizium anisopliae (Deuteromycetes) against Ixodes scapularis (Acari: Ixodidae) engorging on Peromyscus leucopus","volume":"30","author":"Hornbostel VL","year":"2005","unstructured":"Hornbostel VL, Ostfeld RS, Benjamin MA. 2005. Effectiveness of Metarhizium anisopliae (Deuteromycetes) against Ixodes scapularis (Acari: Ixodidae) engorging on Peromyscus leucopus. J Vector Ecol 30:91\u2013101.","journal-title":"J Vector Ecol"},{"key":"e_1_3_4_55_2","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/jiu005"},{"key":"e_1_3_4_56_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0405763102"},{"key":"e_1_3_4_57_2","doi-asserted-by":"publisher","DOI":"10.1098\/rspb.2007.1208"},{"key":"e_1_3_4_58_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.0021-8790.2001.00558.x"},{"key":"e_1_3_4_59_2","doi-asserted-by":"publisher","DOI":"10.1093\/jipm\/pmx024"},{"key":"e_1_3_4_60_2","doi-asserted-by":"publisher","DOI":"10.4269\/ajtmh.2003.68.447"},{"key":"e_1_3_4_61_2","doi-asserted-by":"publisher","DOI":"10.2307\/3284526"},{"key":"e_1_3_4_62_2","volume-title":"Life on a hostile landscape: success, distributions, and consequences of ectoparasites on their hosts","author":"Arnold E","year":"2015","unstructured":"Arnold E. 2015. Life on a hostile landscape: success, distributions, and consequences of ectoparasites on their hosts. Thesis. University of Illinois at Chicago, Chicago, IL."},{"key":"e_1_3_4_63_2","doi-asserted-by":"publisher","DOI":"10.1080\/03949370.2016.1179683"},{"key":"e_1_3_4_64_2","doi-asserted-by":"publisher","DOI":"10.1093\/jmedent\/29.5.813"},{"key":"e_1_3_4_65_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ttbdis.2010.12.002"},{"key":"e_1_3_4_66_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ttbdis.2014.06.004"},{"key":"e_1_3_4_67_2","doi-asserted-by":"publisher","DOI":"10.1016\/s0966-842x(01)02298-3"},{"key":"e_1_3_4_68_2","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.66.3.1248-1251.1998"},{"key":"e_1_3_4_69_2","doi-asserted-by":"publisher","DOI":"10.2307\/3285006"},{"key":"e_1_3_4_70_2","doi-asserted-by":"publisher","DOI":"10.3389\/fvets.2018.00346"},{"key":"e_1_3_4_71_2","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2016.00385"},{"key":"e_1_3_4_72_2","doi-asserted-by":"publisher","DOI":"10.1017\/S0031182097001868"},{"key":"e_1_3_4_73_2","doi-asserted-by":"publisher","DOI":"10.1093\/jmedent\/15.5-6.537"},{"key":"e_1_3_4_74_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.1604318"},{"key":"e_1_3_4_75_2","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/168.3.687"},{"key":"e_1_3_4_76_2","doi-asserted-by":"publisher","DOI":"10.1093\/jme\/tjz046"},{"key":"e_1_3_4_77_2","doi-asserted-by":"publisher","DOI":"10.1128\/mSphere.00151-17"},{"key":"e_1_3_4_78_2","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gks1263"}],"container-title":["Applied and Environmental Microbiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/AEM.02370-20","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/AEM.02370-20","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,8,16]],"date-time":"2024-08-16T19:51:59Z","timestamp":1723837919000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.asm.org\/doi\/10.1128\/AEM.02370-20"}},"subtitle":[],"editor":[{"given":"Karyn N.","family":"Johnson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2021,1,4]]},"references-count":77,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2021,1,4]]}},"alternative-id":["10.1128\/AEM.02370-20"],"URL":"https:\/\/doi.org\/10.1128\/aem.02370-20","relation":{},"ISSN":["0099-2240","1098-5336"],"issn-type":[{"value":"0099-2240","type":"print"},{"value":"1098-5336","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,1,4]]},"assertion":[{"value":"2020-09-28","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-10-29","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-01-04","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e02370-20"}}