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For instance, nasal\n                    <jats:italic>Staphylococcus<\/jats:italic>\n                    species strains can inhibit the growth of other bacteria through the production of nonribosomal peptides and ribosomally synthesized and posttranslationally modified peptides. In contrast, bacteria engaging in exploitation competition modify the external environment to prevent competitors from growing, usually by hindering access to or depleting essential nutrients. As the nasal cavity is a nutrient-limited environment, we hypothesized that exploitation competition occurs in this system. We determined that\n                    <jats:named-content content-type=\"genus-species\">Corynebacterium propinquum<\/jats:named-content>\n                    produces an iron-chelating siderophore, and this iron-sequestering molecule correlates with the ability to inhibit the growth of coagulase-negative staphylococci. Furthermore, we found that the genes required for siderophore production are expressed\n                    <jats:italic>in vivo<\/jats:italic>\n                    . Thus, although siderophore production by bacteria is often considered a virulence trait, our work indicates that bacteria may produce siderophores to compete for limited iron in the human nasal cavity.\n                  <\/jats:p>","DOI":"10.1128\/aem.02406-18","type":"journal-article","created":{"date-parts":[[2018,12,21]],"date-time":"2018-12-21T06:11:24Z","timestamp":1545372684000},"update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":92,"title":["Competition among Nasal Bacteria Suggests a Role for Siderophore-Mediated Interactions in Shaping the Human Nasal Microbiota"],"prefix":"10.1128","volume":"85","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1507-3272","authenticated-orcid":false,"given":"Reed M.","family":"Stubbendieck","sequence":"first","affiliation":[{"name":"Department of Bacteriology, University of Wisconsin\u2014Madison, Madison, Wisconsin, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1387-9061","authenticated-orcid":false,"given":"Daniel S.","family":"May","sequence":"additional","affiliation":[{"name":"Department of Bacteriology, University of Wisconsin\u2014Madison, Madison, Wisconsin, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7209-0717","authenticated-orcid":false,"given":"Marc G.","family":"Chevrette","sequence":"additional","affiliation":[{"name":"Department of Bacteriology, University of Wisconsin\u2014Madison, Madison, Wisconsin, USA"},{"name":"Laboratory of Genetics, University of Wisconsin\u2014Madison, Madison, Wisconsin, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mia I.","family":"Temkin","sequence":"additional","affiliation":[{"name":"Department of Bacteriology, University of Wisconsin\u2014Madison, Madison, Wisconsin, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Evelyn","family":"Wendt-Pienkowski","sequence":"additional","affiliation":[{"name":"Department of Bacteriology, University of Wisconsin\u2014Madison, Madison, Wisconsin, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Julian","family":"Cagnazzo","sequence":"additional","affiliation":[{"name":"Department of Bacteriology, University of Wisconsin\u2014Madison, Madison, Wisconsin, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Caitlin M.","family":"Carlson","sequence":"additional","affiliation":[{"name":"Department of Bacteriology, University of Wisconsin\u2014Madison, Madison, Wisconsin, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6667-4708","authenticated-orcid":false,"given":"James E.","family":"Gern","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin, USA"},{"name":"Department of Medicine, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cameron R.","family":"Currie","sequence":"additional","affiliation":[{"name":"Department of Bacteriology, University of Wisconsin\u2014Madison, Madison, Wisconsin, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"235","reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0028742"},{"key":"e_1_3_3_3_2","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2014.02.008"},{"key":"e_1_3_3_4_2","doi-asserted-by":"publisher","DOI":"10.1097\/00008469-199703001-00009"},{"key":"e_1_3_3_5_2","doi-asserted-by":"publisher","DOI":"10.1113\/jphysiol.2009.176370"},{"key":"e_1_3_3_6_2","doi-asserted-by":"publisher","DOI":"10.1038\/nri3535"},{"key":"e_1_3_3_7_2","doi-asserted-by":"publisher","DOI":"10.1128\/mBio.00974-15"},{"key":"e_1_3_3_8_2","doi-asserted-by":"publisher","DOI":"10.1146\/annurev-micro-091014-104209"},{"key":"e_1_3_3_9_2","doi-asserted-by":"publisher","DOI":"10.1038\/nrmicro1955"},{"key":"e_1_3_3_10_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1574-6976.2011.00301.x"},{"key":"e_1_3_3_11_2","doi-asserted-by":"publisher","DOI":"10.1038\/nrmicro2746"},{"key":"e_1_3_3_12_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1219247110"},{"key":"e_1_3_3_13_2","doi-asserted-by":"publisher","DOI":"10.1038\/nature09415"},{"key":"e_1_3_3_14_2","doi-asserted-by":"publisher","DOI":"10.1111\/1523-1747.ep12724177"},{"key":"e_1_3_3_15_2","doi-asserted-by":"publisher","DOI":"10.1099\/00221287-143-5-1745"},{"key":"e_1_3_3_16_2","doi-asserted-by":"publisher","DOI":"10.1111\/1523-1747.ep12543549"},{"key":"e_1_3_3_17_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.ppat.1005846"},{"key":"e_1_3_3_18_2","first-page":"275","article-title":"Quantitative composition of nasal secretions in normal subjects","volume":"80","author":"Lorin MI","year":"1972","unstructured":"Lorin MI, Gaerlan PF, Mandel ID. 1972. 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