{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,25]],"date-time":"2026-03-25T05:36:24Z","timestamp":1774416984505,"version":"3.50.1"},"reference-count":36,"publisher":"American Society for Microbiology","issue":"11","license":[{"start":{"date-parts":[[2008,6,1]],"date-time":"2008-06-01T00:00:00Z","timestamp":1212278400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["Appl Environ Microbiol"],"published-print":{"date-parts":[[2008,6]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n          <jats:p>\n            In the aftermath of the 2001 anthrax letters, researchers have been exploring ways to predict the production environment of unknown-source microorganisms. Culture medium, presence of agar, culturing temperature, and drying method are just some of the broad spectrum of characteristics an investigator might like to infer. The effects of many of these factors on microorganisms are not well understood, but the complex way in which microbes interact with their environments suggests that numerous analytical techniques measuring different properties will eventually be needed for complete characterization. In this work, we present a Bayesian statistical framework for integrating disparate analytical measurements. We illustrate its application to the problem of characterizing the culture medium of\n            <jats:italic>Bacillus<\/jats:italic>\n            spores using three different mass spectral techniques. The results of our study suggest that integrating data in this way significantly improves the accuracy and robustness of the analyses.\n          <\/jats:p>","DOI":"10.1128\/aem.02526-07","type":"journal-article","created":{"date-parts":[[2008,4,5]],"date-time":"2008-04-05T00:54:07Z","timestamp":1207356847000},"page":"3573-3582","update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":28,"title":["Bayesian-Integrated Microbial Forensics"],"prefix":"10.1128","volume":"74","author":[{"given":"Kristin H.","family":"Jarman","sequence":"first","affiliation":[{"name":"Pacific Northwest National Laboratory, P.O. Box 999, Richland, WA 99352"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Helen W.","family":"Kreuzer-Martin","sequence":"additional","affiliation":[{"name":"Pacific Northwest National Laboratory, P.O. Box 999, Richland, WA 99352"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David S.","family":"Wunschel","sequence":"additional","affiliation":[{"name":"Pacific Northwest National Laboratory, P.O. Box 999, Richland, WA 99352"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nancy B.","family":"Valentine","sequence":"additional","affiliation":[{"name":"Pacific Northwest National Laboratory, P.O. Box 999, Richland, WA 99352"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"John B.","family":"Cliff","sequence":"additional","affiliation":[{"name":"Pacific Northwest National Laboratory, P.O. Box 999, Richland, WA 99352"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Catherine E.","family":"Petersen","sequence":"additional","affiliation":[{"name":"Pacific Northwest National Laboratory, P.O. Box 999, Richland, WA 99352"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Heather A.","family":"Colburn","sequence":"additional","affiliation":[{"name":"Pacific Northwest National Laboratory, P.O. Box 999, Richland, WA 99352"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Karen L.","family":"Wahl","sequence":"additional","affiliation":[{"name":"Pacific Northwest National Laboratory, P.O. Box 999, Richland, WA 99352"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"235","reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1021\/pr060440a"},{"key":"e_1_3_2_3_2","first-page":"703","volume":"39","year":"2006","unstructured":"Bae, S. M., S. M. Yeon, T. S. Kim, and K. J. Lee. 2006. The effect on protein expression of Streptococcus pneumoniae by blood. J. Biochem. Mol. Biol.39:703-708.","journal-title":"J. Biochem. Mol. Biol."},{"key":"e_1_3_2_4_2","unstructured":"Bayesian theory. 2000"},{"key":"e_1_3_2_5_2","unstructured":"Microbial forensics. 2005"},{"key":"e_1_3_2_6_2","first-page":"1","volume":"1","year":"1990","unstructured":"Bridson, E. Y. 1990. Media in microbiology. Rev. Med. Microbiol.1:1-9.","journal-title":"Rev. Med. Microbiol."},{"key":"e_1_3_2_7_2","doi-asserted-by":"publisher","DOI":"10.1128\/AEM.71.5.2209-2213.2005"},{"key":"e_1_3_2_8_2","doi-asserted-by":"publisher","DOI":"10.1080\/10408410500304082"},{"key":"e_1_3_2_9_2","doi-asserted-by":"publisher","DOI":"10.1128\/AEM.71.11.6524-6530.2005"},{"key":"e_1_3_2_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/0016-7037(96)00263-3"},{"key":"e_1_3_2_11_2","unstructured":"Probabilistic networks and expert systems. 1999"},{"key":"e_1_3_2_12_2","doi-asserted-by":"publisher","DOI":"10.1016\/0016-7037(78)90199-0"},{"key":"e_1_3_2_13_2","doi-asserted-by":"publisher","DOI":"10.1016\/0016-7037(81)90244-1"},{"key":"e_1_3_2_14_2","first-page":"1374","volume":"214","year":"1980","unstructured":"Estep, M. 1980. Hydrogen isotope ratios of mouse tissues are influenced by a variety of factors other than diet. Science214:1374-1376.","journal-title":"Science"},{"key":"e_1_3_2_15_2","first-page":"1","volume":"1","year":"1980","unstructured":"Fritz, P., and J. C. Fontes. 1980. The terrestrial environment, A, vol. 1, p. 1-19. Elsevier, New York, NY.","journal-title":"The terrestrial environment"},{"key":"e_1_3_2_16_2","unstructured":"Bayesian data analysis. 2000"},{"key":"e_1_3_2_17_2","unstructured":"Molecular biological methods for Bacillus. 1990"},{"key":"e_1_3_2_18_2","doi-asserted-by":"publisher","DOI":"10.1139\/m60-022"},{"key":"e_1_3_2_19_2","doi-asserted-by":"publisher","DOI":"10.1099\/00221287-137-4-725"},{"key":"e_1_3_2_20_2","doi-asserted-by":"crossref","unstructured":"Jensen F. V. 2001. Bayesian networks and decision graphs. Springer-Verlag Inc. New York NY.","DOI":"10.1007\/978-1-4757-3502-4"},{"key":"e_1_3_2_21_2","doi-asserted-by":"publisher","DOI":"10.1128\/AEM.02906-06"},{"key":"e_1_3_2_22_2","first-page":"961","volume":"49","year":"2004","unstructured":"Kreuzer-Martin, H. W., L. A. Chesson, M. J. Lott, J. V. Dorigan, and J. R. Ehleringer. 2004. Stable isotope ratios as a tool in microbial forensics, 2. Isotopic variation among different growth media as a tool for sourcing origins of bacterial cells or spores. J. Forensic Sci.49:961-967.","journal-title":"J. Forensic Sci."},{"key":"e_1_3_2_23_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.252747799"},{"key":"e_1_3_2_24_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9258(18)62213-6"},{"key":"e_1_3_2_25_2","doi-asserted-by":"publisher","DOI":"10.1074\/mcp.D500006-MCP200"},{"key":"e_1_3_2_26_2","unstructured":"Probabilistic reasoning in expert systems: theory and algorithms. 1990"},{"key":"e_1_3_2_27_2","unstructured":"Bayesian artificial intelligence. 2003"},{"key":"e_1_3_2_28_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.1060331"},{"key":"e_1_3_2_29_2","unstructured":"Causality: models reasoning and inference. 2000"},{"key":"e_1_3_2_30_2","doi-asserted-by":"publisher","DOI":"10.1006\/bbrc.2001.2022"},{"key":"e_1_3_2_31_2","doi-asserted-by":"publisher","DOI":"10.1364\/AO.42.006205"},{"key":"e_1_3_2_32_2","doi-asserted-by":"publisher","DOI":"10.1128\/AEM.71.1.58-64.2005"},{"key":"e_1_3_2_33_2","first-page":"U121","volume":"226","year":"2003","unstructured":"Wahl, K. L., N. B. Valentine, S. C. Wunschel, D. S. Wunschel, K. H. Jarman, and C. E. Petersen. 2003. Microorganism analysis and identification by MALDI-TOF-MS. Abstr. Pap. Am. Chem. Soc.226:U121.","journal-title":"Pap. Am. Chem. Soc."},{"key":"e_1_3_2_34_2","first-page":"8","volume":"541","year":"1994","unstructured":"White, D. C., D. B. Ringelberg, D. B. Hedrick, and D. E. Nivens. 1994. Rapid identification of microbes and environmental matrices\u2014characterization of signature lipids. Mass Spectrom. Characterization Microorg.541:8-17.","journal-title":"Characterization Microorg."},{"key":"e_1_3_2_35_2","doi-asserted-by":"publisher","DOI":"10.1021\/ac034959r"},{"key":"e_1_3_2_36_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.mimet.2005.04.033"},{"key":"e_1_3_2_37_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jasms.2004.12.004"}],"container-title":["Applied and Environmental Microbiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/AEM.02526-07","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/AEM.02526-07","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,2,23]],"date-time":"2022-02-23T16:32:22Z","timestamp":1645633942000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.asm.org\/doi\/10.1128\/AEM.02526-07"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,6]]},"references-count":36,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2008,6]]}},"alternative-id":["10.1128\/AEM.02526-07"],"URL":"https:\/\/doi.org\/10.1128\/aem.02526-07","relation":{},"ISSN":["0099-2240","1098-5336"],"issn-type":[{"value":"0099-2240","type":"print"},{"value":"1098-5336","type":"electronic"}],"subject":[],"published":{"date-parts":[[2008,6]]},"assertion":[{"value":"2007-11-08","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2008-03-23","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2008-06-01","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}