{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,4]],"date-time":"2026-10-04T03:33:51Z","timestamp":1791084831683,"version":"4.1.0"},"reference-count":75,"publisher":"American Society for Microbiology","issue":"5","license":[{"start":{"date-parts":[[2013,3,1]],"date-time":"2013-03-01T00:00:00Z","timestamp":1362096000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["Appl Environ Microbiol"],"published-print":{"date-parts":[[2013,3]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n          <jats:p>\n            Comparative analysis of\n            <jats:italic>ospC<\/jats:italic>\n            genes from 127\n            <jats:named-content content-type=\"genus-species\">Borrelia burgdorferi<\/jats:named-content>\n            sensu stricto strains collected in European and North American regions where Lyme disease is endemic and where it is not endemic revealed a close relatedness of geographically distinct populations.\n            <jats:italic>ospC<\/jats:italic>\n            alleles A, B, and L were detected on both continents in vectors and hosts, including humans. Six\n            <jats:italic>ospC<\/jats:italic>\n            alleles, A, B, L, Q, R, and V, were prevalent in Europe; 4 of them were detected in samples of human origin. Ten\n            <jats:italic>ospC<\/jats:italic>\n            alleles, A, B, D, E3, F, G, H, H3, I3, and M, were identified in the far-western United States. Four\n            <jats:italic>ospC<\/jats:italic>\n            alleles, B, G, H, and L, were abundant in the southeastern United States. Here we present the first expanded analysis of\n            <jats:italic>ospC<\/jats:italic>\n            alleles of\n            <jats:named-content content-type=\"genus-species\">B. burgdorferi<\/jats:named-content>\n            strains from the southeastern United States with respect to their relatedness to strains from other North American and European localities. We demonstrate that\n            <jats:italic>ospC<\/jats:italic>\n            genotypes commonly associated with human Lyme disease in European and North American regions where the disease is endemic were detected in\n            <jats:named-content content-type=\"genus-species\">B. burgdorferi<\/jats:named-content>\n            strains isolated from the non-human-biting tick\n            <jats:named-content content-type=\"genus-species\">Ixodes affinis<\/jats:named-content>\n            and rodent hosts in the southeastern United States. We discovered that some\n            <jats:italic>ospC<\/jats:italic>\n            alleles previously known only from Europe are widely distributed in the southeastern United States, a finding that confirms the hypothesis of transoceanic migration of\n            <jats:named-content content-type=\"genus-species\">Borrelia<\/jats:named-content>\n            species.\n          <\/jats:p>","DOI":"10.1128\/aem.02749-12","type":"journal-article","created":{"date-parts":[[2012,12,22]],"date-time":"2012-12-22T07:03:55Z","timestamp":1356159835000},"page":"1444-1453","update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":45,"title":["Detection of Borrelia burgdorferi Sensu Stricto\n            <i>ospC<\/i>\n            Alleles Associated with Human Lyme Borreliosis Worldwide in Non-Human-Biting Tick Ixodes affinis and Rodent Hosts in Southeastern United States"],"prefix":"10.1128","volume":"79","author":[{"given":"Nataliia","family":"Rudenko","sequence":"first","affiliation":[{"name":"Biology Centre v.v.i., Institute of Parasitology AS CR, \u010cesk\u00e9 Bud\u011bjovice, Czech Republic"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maryna","family":"Golovchenko","sequence":"additional","affiliation":[{"name":"Biology Centre v.v.i., Institute of Parasitology AS CR, \u010cesk\u00e9 Bud\u011bjovice, Czech Republic"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"V\u00e1clav","family":"H\u00f6nig","sequence":"additional","affiliation":[{"name":"Biology Centre v.v.i., Institute of Parasitology AS CR, \u010cesk\u00e9 Bud\u011bjovice, Czech Republic"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nadja","family":"Mall\u00e1tov\u00e1","sequence":"additional","affiliation":[{"name":"Laboratory of Mycology and Parasitology, Regional Hospital \u010cesk\u00e9 Bud\u011bjovice, \u010cesk\u00e9 Bud\u011bjovice, Czech Republic"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lenka","family":"Krbkov\u00e1","sequence":"additional","affiliation":[{"name":"Department of Pediatric Infectious Diseases, Faculty Hospital in Brno, Brno, Czech Republic"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter","family":"Mikul\u00e1\u0161ek","sequence":"additional","affiliation":[{"name":"Department of Pediatric Infectious Diseases, Faculty Hospital in Brno, Brno, Czech Republic"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Natalia","family":"Fedorova","sequence":"additional","affiliation":[{"name":"Department of Environmental Science, Policy and Management, University of California, Berkeley, California, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Natalia M.","family":"Belfiore","sequence":"additional","affiliation":[{"name":"Department of Biology, University of Tampa, Tampa, Florida, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Libor","family":"Grubhoffer","sequence":"additional","affiliation":[{"name":"Biology Centre v.v.i., Institute of Parasitology AS CR, \u010cesk\u00e9 Bud\u011bjovice, Czech Republic"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert S.","family":"Lane","sequence":"additional","affiliation":[{"name":"Department of Environmental Science, Policy and Management, University of California, Berkeley, California, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"suffix":"Jr.","given":"James H.","family":"Oliver","sequence":"additional","affiliation":[{"name":"James H. 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