{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T23:51:48Z","timestamp":1790380308461,"version":"4.1.0"},"reference-count":35,"publisher":"American Society for Microbiology","issue":"7","license":[{"start":{"date-parts":[[2020,3,18]],"date-time":"2020-03-18T00:00:00Z","timestamp":1584489600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["Appl Environ Microbiol"],"published-print":{"date-parts":[[2020,3,18]]},"abstract":"<jats:p>\n                    This study investigated the effect of\n                    <jats:named-content content-type=\"genus-species\">Akkermansia muciniphila<\/jats:named-content>\n                    on fatty liver disease. Although some research about the effects of\n                    <jats:italic>A. muciniphila<\/jats:italic>\n                    on host health has been published, study of the relationship between\n                    <jats:italic>A. muciniphila<\/jats:italic>\n                    administration and fatty liver, as well as changes in the gut microbiota, has not been conducted. In this study, we demonstrated that\n                    <jats:named-content content-type=\"genus-species\">A. muciniphila<\/jats:named-content>\n                    prevented fatty liver disease by regulation of the expression of genes that regulate fat synthesis and inflammation in the liver.\n                  <\/jats:p>","DOI":"10.1128\/aem.03004-19","type":"journal-article","created":{"date-parts":[[2020,1,20]],"date-time":"2020-01-20T04:42:28Z","timestamp":1579495348000},"update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":189,"title":["Akkermansia muciniphila Prevents Fatty Liver Disease, Decreases Serum Triglycerides, and Maintains Gut Homeostasis"],"prefix":"10.1128","volume":"86","author":[{"given":"Sejeong","family":"Kim","sequence":"first","affiliation":[{"name":"Risk Analysis Research Center, Seoul, South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yewon","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Food and Nutrition, Sookmyung Women\u2019s University, Seoul, South Korea"},{"name":"Risk Analysis Research Center, Seoul, South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yujin","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Food and Nutrition, Sookmyung Women\u2019s University, Seoul, South Korea"},{"name":"Risk Analysis Research Center, Seoul, South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yeongeun","family":"Seo","sequence":"additional","affiliation":[{"name":"Department of Food and Nutrition, Sookmyung Women\u2019s University, Seoul, South Korea"},{"name":"Risk Analysis Research Center, Seoul, South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Heeyoung","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Food and Nutrition, Sookmyung Women\u2019s University, Seoul, South Korea"},{"name":"Risk Analysis Research Center, Seoul, South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jimyeong","family":"Ha","sequence":"additional","affiliation":[{"name":"Department of Food and Nutrition, Sookmyung Women\u2019s University, Seoul, South Korea"},{"name":"Risk Analysis Research Center, Seoul, South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeeyeon","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Food and Nutrition, Sookmyung Women\u2019s University, Seoul, South Korea"},{"name":"Risk Analysis Research Center, Seoul, South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yukyung","family":"Choi","sequence":"additional","affiliation":[{"name":"Department of Food and Nutrition, Sookmyung Women\u2019s University, Seoul, South Korea"},{"name":"Risk Analysis Research Center, Seoul, South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hyemin","family":"Oh","sequence":"additional","affiliation":[{"name":"Department of Food and Nutrition, Sookmyung Women\u2019s University, Seoul, South Korea"},{"name":"Risk Analysis Research Center, Seoul, South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yohan","family":"Yoon","sequence":"additional","affiliation":[{"name":"Department of Food and Nutrition, Sookmyung Women\u2019s University, Seoul, South Korea"},{"name":"Risk Analysis Research Center, Seoul, South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"235","reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.5851\/kosfa.2018.e62"},{"key":"e_1_3_3_3_2","doi-asserted-by":"publisher","DOI":"10.1007\/s12263-011-0229-7"},{"key":"e_1_3_3_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(03)12489-0"},{"key":"e_1_3_3_5_2","doi-asserted-by":"publisher","DOI":"10.1038\/nutd.2014.23"},{"key":"e_1_3_3_6_2","doi-asserted-by":"publisher","DOI":"10.1038\/nature05414"},{"key":"e_1_3_3_7_2","doi-asserted-by":"publisher","DOI":"10.1038\/nrd2505"},{"key":"e_1_3_3_8_2","doi-asserted-by":"publisher","DOI":"10.1099\/ijs.0.02873-0"},{"key":"e_1_3_3_9_2","doi-asserted-by":"publisher","DOI":"10.1128\/AEM.01477-07"},{"key":"e_1_3_3_10_2","doi-asserted-by":"publisher","DOI":"10.1038\/ni.3400"},{"key":"e_1_3_3_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2013.12.016"},{"key":"e_1_3_3_12_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0016876"},{"key":"e_1_3_3_13_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1219451110"},{"key":"e_1_3_3_14_2","doi-asserted-by":"publisher","DOI":"10.1136\/gutjnl-2014-306928"},{"key":"e_1_3_3_15_2","doi-asserted-by":"publisher","DOI":"10.1038\/oby.2012.110"},{"key":"e_1_3_3_16_2","doi-asserted-by":"publisher","DOI":"10.1097\/MIB.0b013e31827fec6d"},{"key":"e_1_3_3_17_2","doi-asserted-by":"publisher","DOI":"10.3389\/fmicb.2017.01804"},{"key":"e_1_3_3_18_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.molmet.2016.06.003"},{"key":"e_1_3_3_19_2","doi-asserted-by":"publisher","DOI":"10.1242\/dmm.011981"},{"key":"e_1_3_3_20_2","doi-asserted-by":"publisher","DOI":"10.1097\/MPG.0b013e318284abb5"},{"key":"e_1_3_3_21_2","doi-asserted-by":"publisher","DOI":"10.1186\/s12866-019-1557-9"},{"key":"e_1_3_3_22_2","doi-asserted-by":"publisher","DOI":"10.4161\/gmic.20168"},{"key":"e_1_3_3_23_2","doi-asserted-by":"publisher","DOI":"10.1128\/mBio.01438-14"},{"key":"e_1_3_3_24_2","doi-asserted-by":"publisher","DOI":"10.3389\/fmicb.2011.00166"},{"key":"e_1_3_3_25_2","doi-asserted-by":"publisher","DOI":"10.1155\/2015\/287348"},{"key":"e_1_3_3_26_2","doi-asserted-by":"publisher","DOI":"10.1111\/1469-0691.12140"},{"key":"e_1_3_3_27_2","doi-asserted-by":"publisher","DOI":"10.5851\/kosfa.2018.38.3.554"},{"key":"e_1_3_3_28_2","doi-asserted-by":"publisher","DOI":"10.5851\/kosfa.2018.e38"},{"key":"e_1_3_3_29_2","doi-asserted-by":"publisher","DOI":"10.1093\/bioinformatics\/btu170"},{"key":"e_1_3_3_30_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pcbi.1002195"},{"key":"e_1_3_3_31_2","doi-asserted-by":"publisher","DOI":"10.1093\/bioinformatics\/btq461"},{"key":"e_1_3_3_32_2","doi-asserted-by":"publisher","DOI":"10.1006\/meth.2001.1262"},{"key":"e_1_3_3_33_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0065641"},{"key":"e_1_3_3_34_2","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2164-14-758"},{"key":"e_1_3_3_35_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0047713"},{"key":"e_1_3_3_36_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajpath.2013.08.004"}],"container-title":["Applied and Environmental Microbiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/AEM.03004-19","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/AEM.03004-19","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,2,23]],"date-time":"2022-02-23T14:14:13Z","timestamp":1645625653000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.asm.org\/doi\/10.1128\/AEM.03004-19"}},"subtitle":[],"editor":[{"given":"Harold L.","family":"Drake","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2020,3,18]]},"references-count":35,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2020,3,18]]}},"alternative-id":["10.1128\/AEM.03004-19"],"URL":"https:\/\/doi.org\/10.1128\/aem.03004-19","relation":{},"ISSN":["0099-2240","1098-5336"],"issn-type":[{"value":"0099-2240","type":"print"},{"value":"1098-5336","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,3,18]]},"assertion":[{"value":"2019-12-22","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-01-12","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-03-18","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e03004-19"}}