{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T06:42:17Z","timestamp":1791182537995,"version":"4.1.0"},"reference-count":32,"publisher":"American Society for Microbiology","issue":"7","license":[{"start":{"date-parts":[[2014,4,1]],"date-time":"2014-04-01T00:00:00Z","timestamp":1396310400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["Appl Environ Microbiol"],"published-print":{"date-parts":[[2014,4]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n          <jats:p>\n            <jats:named-content content-type=\"genus-species\">Legionella pneumophila<\/jats:named-content>\n            serogroup 1 causes Legionnaires' disease. Water systems contaminated with\n            <jats:named-content content-type=\"genus-species\">Legionella<\/jats:named-content>\n            are the implicated sources of Legionnaires' disease. This study analyzed\n            <jats:named-content content-type=\"genus-species\">L. pneumophila<\/jats:named-content>\n            serogroup 1 strains in China using sequence-based typing. Strains were isolated from cooling towers (\n            <jats:italic>n<\/jats:italic>\n            = 96), hot springs (\n            <jats:italic>n<\/jats:italic>\n            = 42), and potable water systems (\n            <jats:italic>n<\/jats:italic>\n            = 26). Isolates from cooling towers, hot springs, and potable water systems were divided into 25 sequence types (STs; index of discrimination [IOD], 0.711), 19 STs (IOD, 0.934), and 3 STs (IOD, 0.151), respectively. The genetic variation among the potable water isolates was lower than that among cooling tower and hot spring isolates. ST1 was the predominant type, accounting for 49.4% of analyzed strains (\n            <jats:italic>n<\/jats:italic>\n            = 81), followed by ST154. With the exception of two strains, all potable water isolates (92.3%) belonged to ST1. In contrast, 53.1% (51\/96) and only 14.3% (6\/42) of cooling tower and hot spring, respectively, isolates belonged to ST1. There were differences in the distributions of clone groups among the water sources. The comparisons among\n            <jats:named-content content-type=\"genus-species\">L. pneumophila<\/jats:named-content>\n            strains isolated in China, Japan, and South Korea revealed that similar clones (ST1 complex and ST154 complex) exist in these countries. In conclusion, in China, STs had several unique allelic profiles, and ST1 was the most prevalent sequence type of environmental\n            <jats:named-content content-type=\"genus-species\">L. pneumophila<\/jats:named-content>\n            serogroup 1 isolates, similar to its prevalence in Japan and South Korea.\n          <\/jats:p>","DOI":"10.1128\/aem.03844-13","type":"journal-article","created":{"date-parts":[[2014,1,25]],"date-time":"2014-01-25T05:11:31Z","timestamp":1390626691000},"page":"2150-2157","update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":37,"title":["Distribution of Sequence-Based Types of Legionella pneumophila Serogroup 1 Strains Isolated from Cooling Towers, Hot Springs, and Potable Water Systems in China"],"prefix":"10.1128","volume":"80","author":[{"given":"Tian","family":"Qin","sequence":"first","affiliation":[{"name":"National Institute for Communicable Disease Control and Prevention and State Key Laboratory for Infectious Disease Prevention and Control, Chinese Centre for Disease Control and Prevention, Beijing, China"},{"name":"Collaborative Innovation Centre for Diagnosis and Treatment of Infectious Diseases, Hangzhou, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Haijian","family":"Zhou","sequence":"additional","affiliation":[{"name":"National Institute for Communicable Disease Control and Prevention and State Key Laboratory for Infectious Disease Prevention and Control, Chinese Centre for Disease Control and Prevention, Beijing, China"},{"name":"Collaborative Innovation Centre for Diagnosis and Treatment of Infectious Diseases, Hangzhou, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hongyu","family":"Ren","sequence":"additional","affiliation":[{"name":"National Institute for Communicable Disease Control and Prevention and State Key Laboratory for Infectious Disease Prevention and Control, Chinese Centre for Disease Control and Prevention, Beijing, China"},{"name":"Collaborative Innovation Centre for Diagnosis and Treatment of Infectious Diseases, Hangzhou, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hong","family":"Guan","sequence":"additional","affiliation":[{"name":"National Institute for Communicable Disease Control and Prevention and State Key Laboratory for Infectious Disease Prevention and Control, Chinese Centre for Disease Control and Prevention, Beijing, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Machao","family":"Li","sequence":"additional","affiliation":[{"name":"National Institute for Communicable Disease Control and Prevention and State Key Laboratory for Infectious Disease Prevention and Control, Chinese Centre for Disease Control and Prevention, Beijing, China"},{"name":"Collaborative Innovation Centre for Diagnosis and Treatment of Infectious Diseases, Hangzhou, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bingqing","family":"Zhu","sequence":"additional","affiliation":[{"name":"National Institute for Communicable Disease Control and Prevention and State Key Laboratory for Infectious Disease Prevention and Control, Chinese Centre for Disease Control and Prevention, Beijing, China"},{"name":"Collaborative Innovation Centre for Diagnosis and Treatment of Infectious Diseases, Hangzhou, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhujun","family":"Shao","sequence":"additional","affiliation":[{"name":"National Institute for Communicable Disease Control and Prevention and State Key Laboratory for Infectious Disease Prevention and Control, Chinese Centre for Disease Control and Prevention, Beijing, China"},{"name":"Collaborative Innovation Centre for Diagnosis and Treatment of Infectious Diseases, Hangzhou, 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A.","family":"Elkins","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2014,4]]},"references-count":32,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2014,4]]}},"alternative-id":["10.1128\/AEM.03844-13"],"URL":"https:\/\/doi.org\/10.1128\/aem.03844-13","relation":{},"ISSN":["0099-2240","1098-5336"],"issn-type":[{"value":"0099-2240","type":"print"},{"value":"1098-5336","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,4]]},"assertion":[{"value":"2013-11-19","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2014-01-22","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2014-03-11","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}