{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,2]],"date-time":"2026-10-02T11:35:50Z","timestamp":1790940950762,"version":"4.1.0"},"reference-count":44,"publisher":"American Society for Microbiology","issue":"2","license":[{"start":{"date-parts":[[1999,2,1]],"date-time":"1999-02-01T00:00:00Z","timestamp":917827200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["Appl Environ Microbiol"],"published-print":{"date-parts":[[1999,2]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n          <jats:p>\n            The combined effects of Mn and oxygen on lignin peroxidase (LIP) activity and isozyme composition in\n            <jats:italic>Phanerochaete chrysosporium<\/jats:italic>\n            were studied by using shallow stationary cultures grown in the presence of limited or excess N. When no Mn was added, LIP was formed in both N-limited and N-excess cultures exposed to air, but no LIP activity was observed at Mn concentrations greater than 13 mg\/liter. In oxygen-flushed, N-excess cultures, LIP was formed at all Mn concentrations, and the peak LIP activity values in the extracellular fluid were nearly identical in the presence of Mn concentrations ranging from 3 to 1,500 mg\/liter. When the availability of oxygen to cultures exposed to air was increased by growing the fungus under nonimmersed liquid conditions, higher levels of Mn were needed to suppress LIP formation compared with the levels needed in shallow stationary cultures. The composition of LIP isozymes was affected by the levels of N and Mn. Addition of veratryl alcohol to cultures exposed to air did not eliminate the suppressive effect of Mn on LIP formation. A deficiency of Mn in N-excess cultures resulted in lower biomass and a lower rate of glucose consumption than in the presence of Mn. In addition, almost no activity of the antioxidant enzyme Mn superoxide dismutase was observed in Mn-deficient, N-excess cultures, but the activity of this enzyme increased as the Mn concentration increased from 3 to 13 mg\/liter. No Zn\/Cu superoxide dismutase activity was observed in N-excess cultures regardless of the Mn concentration.\n          <\/jats:p>","DOI":"10.1128\/aem.65.2.483-488.1999","type":"journal-article","created":{"date-parts":[[2019,12,19]],"date-time":"2019-12-19T19:46:28Z","timestamp":1576784788000},"page":"483-488","update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":48,"title":["Manganese Deficiency Can Replace High Oxygen Levels Needed for Lignin Peroxidase Formation by\n            <i>Phanerochaete chrysosporium<\/i>"],"prefix":"10.1128","volume":"65","author":[{"given":"Nathan","family":"Rothschild","sequence":"first","affiliation":[{"name":"<!--label omitted: 1-->MIGAL, South Industrial Zone, Kiryat Shmona 10200,1"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ayala","family":"Levkowitz","sequence":"additional","affiliation":[{"name":"<!--label omitted: 1-->MIGAL, South Industrial Zone, Kiryat Shmona 10200,1"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yitzhak","family":"Hadar","sequence":"additional","affiliation":[{"name":"<!--label omitted: 2-->Department of Plant Pathology &amp; Microbiology, Faculty of Agriculture, Hebrew University of Jerusalem, Rehovot 76200,2 and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carlos G.","family":"Dosoretz","sequence":"additional","affiliation":[{"name":"<!--label omitted: 1-->MIGAL, South Industrial Zone, Kiryat Shmona 10200,1"},{"name":"<!--label omitted: 3-->Department of Biotechnology &amp; Environmental Sciences, School of Science &amp; Technology, Academic College Tel-Hai, Upper Galilee 10120,3Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"235","reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/0003-2697(71)90370-8"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1128\/aem.56.1.210-217.1990"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/0014-5793(92)81342-J"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.1128\/jb.173.13.4101-4106.1991"},{"key":"e_1_3_2_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/0891-5849(88)90104-9"},{"key":"e_1_3_2_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/0003-9861(92)90282-2"},{"key":"e_1_3_2_8_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1574-6968.1990.tb04233.x"},{"key":"e_1_3_2_9_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF00170937"},{"key":"e_1_3_2_10_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF02922605"},{"key":"e_1_3_2_11_2","doi-asserted-by":"publisher","DOI":"10.1128\/aem.59.6.1919-1926.1993"},{"key":"e_1_3_2_12_2","unstructured":"Dosoretz\nC. 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C.\nAnder\nP.\n1993\n43\n48\nForbitec Editions\nLisbon Portugal"},{"key":"e_1_3_2_13_2","doi-asserted-by":"publisher","DOI":"10.1128\/aem.49.2.299-304.1985"},{"key":"e_1_3_2_14_2","doi-asserted-by":"publisher","DOI":"10.1351\/pac198759020257"},{"key":"e_1_3_2_15_2","doi-asserted-by":"publisher","DOI":"10.1128\/mr.57.3.605-622.1993"},{"key":"e_1_3_2_16_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9258(19)74369-5"},{"key":"e_1_3_2_17_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1574-6976.1994.tb00105.x"},{"key":"e_1_3_2_18_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF00165892"},{"key":"e_1_3_2_19_2","doi-asserted-by":"publisher","DOI":"10.1021\/bi00023a025"},{"key":"e_1_3_2_20_2","doi-asserted-by":"publisher","DOI":"10.1016\/0141-0229(86)90006-2"},{"key":"e_1_3_2_21_2","unstructured":"Korc\nM.\nManganese as a modulator of signal transduction pathways\nEssential and toxic trace elements in human health and disease: an update.\nPrasad\nA. S.\n1993\n235\n255\nWiley-Liss Inc.\nNew York N.Y"},{"key":"e_1_3_2_22_2","doi-asserted-by":"publisher","DOI":"10.1016\/0014-5793(84)80327-0"},{"key":"e_1_3_2_23_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF00499861"},{"key":"e_1_3_2_24_2","doi-asserted-by":"publisher","DOI":"10.1128\/aem.60.9.3447-3449.1994"},{"key":"e_1_3_2_25_2","doi-asserted-by":"publisher","DOI":"10.1128\/aem.61.1.341-345.1995"},{"key":"e_1_3_2_26_2","doi-asserted-by":"publisher","DOI":"10.1128\/aem.61.5.1881-1887.1995"},{"key":"e_1_3_2_27_2","doi-asserted-by":"publisher","DOI":"10.1128\/aem.58.5.1740-1745.1992"},{"key":"e_1_3_2_28_2","first-page":"3521","article-title":"Intracellular oxygen-metabolizing enzymes of Phanerochaete chrysosporium.","volume":"133","author":"Morpeth F. F.","year":"1987","unstructured":"Morpeth F. F. Intracellular oxygen-metabolizing enzymes of Phanerochaete chrysosporium. J. Gen. Microbiol. 133 1987 3521 3525","journal-title":"J. Gen. 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Biotechnology in the Pulp and Paper Industry Montreal Quebec Canada\n1998\nB77\nB79"},{"key":"e_1_3_2_37_2","doi-asserted-by":"publisher","DOI":"10.1128\/aem.61.5.1833-1838.1995"},{"key":"e_1_3_2_38_2","doi-asserted-by":"publisher","DOI":"10.1128\/aem.63.3.857-861.1997"},{"key":"e_1_3_2_39_2","doi-asserted-by":"publisher","DOI":"10.1128\/jb.174.15.5036-5042.1992"},{"key":"e_1_3_2_40_2","doi-asserted-by":"publisher","DOI":"10.1016\/0891-5849(92)90072-O"},{"key":"e_1_3_2_41_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.221.4611.661"},{"key":"e_1_3_2_42_2","doi-asserted-by":"publisher","DOI":"10.1016\/0076-6879(88)61025-1"},{"key":"e_1_3_2_43_2","doi-asserted-by":"publisher","DOI":"10.1128\/aem.54.2.466-472.1988"},{"key":"e_1_3_2_44_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF00258138"},{"key":"e_1_3_2_45_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.83.11.3820"}],"container-title":["Applied and Environmental Microbiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/AEM.65.2.483-488.1999","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/AEM.65.2.483-488.1999","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,2,23]],"date-time":"2022-02-23T08:10:08Z","timestamp":1645603808000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.asm.org\/doi\/10.1128\/AEM.65.2.483-488.1999"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1999,2]]},"references-count":44,"journal-issue":{"issue":"2","published-print":{"date-parts":[[1999,2]]}},"alternative-id":["10.1128\/AEM.65.2.483-488.1999"],"URL":"https:\/\/doi.org\/10.1128\/aem.65.2.483-488.1999","relation":{},"ISSN":["0099-2240","1098-5336"],"issn-type":[{"value":"0099-2240","type":"print"},{"value":"1098-5336","type":"electronic"}],"subject":[],"published":{"date-parts":[[1999,2]]},"assertion":[{"value":"1998-09-17","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"1998-11-10","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"1999-02-01","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}