{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,4]],"date-time":"2026-10-04T12:49:06Z","timestamp":1791118146716,"version":"4.1.0"},"reference-count":39,"publisher":"American Society for Microbiology","issue":"6","license":[{"start":{"date-parts":[[2000,6,1]],"date-time":"2000-06-01T00:00:00Z","timestamp":959817600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["Appl Environ Microbiol"],"published-print":{"date-parts":[[2000,6]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n          <jats:p>\n            We have characterized the nucleotide sequences of the 70-kDa heat shock protein (HSP70) genes of\n            <jats:italic>Cryptosporidium baileyi<\/jats:italic>\n            ,\n            <jats:italic>C. felis<\/jats:italic>\n            ,\n            <jats:italic>C. meleagridis<\/jats:italic>\n            ,\n            <jats:italic>C. muris<\/jats:italic>\n            ,\n            <jats:italic>C. serpentis<\/jats:italic>\n            ,\n            <jats:italic>C. wrairi<\/jats:italic>\n            , and\n            <jats:italic>C. parvum<\/jats:italic>\n            from various animals. Results of the phylogenetic analysis revealed the presence of several genetically distinct species in the genus\n            <jats:italic>Cryptosporidium<\/jats:italic>\n            and eight distinct genotypes within the species\n            <jats:italic>C. parvum<\/jats:italic>\n            . Some of the latter may represent cryptic species. The phylogenetic tree constructed from these sequences is in agreement with our previous results based on the small-subunit rRNA genes of\n            <jats:italic>Cryptosporidium<\/jats:italic>\n            parasites. The\n            <jats:italic>Cryptosporidium<\/jats:italic>\n            species formed two major clades: isolates of\n            <jats:italic>C. muris<\/jats:italic>\n            and\n            <jats:italic>C. serpentis<\/jats:italic>\n            formed the first major group, while isolates of\n            <jats:italic>C. felis<\/jats:italic>\n            ,\n            <jats:italic>C. meleagridis<\/jats:italic>\n            ,\n            <jats:italic>C. wrairi<\/jats:italic>\n            , and eight genotypes of\n            <jats:italic>C. parvum<\/jats:italic>\n            formed the second major group. Sequence variations were also observed between\n            <jats:italic>C. muris<\/jats:italic>\n            isolates from ruminants and rodents. The HSP70 gene provides another useful locus for phylogenetic analysis of the genus\n            <jats:italic>Cryptosporidium<\/jats:italic>\n            .\n          <\/jats:p>","DOI":"10.1128\/aem.66.6.2385-2391.2000","type":"journal-article","created":{"date-parts":[[2002,7,27]],"date-time":"2002-07-27T09:55:30Z","timestamp":1027763730000},"page":"2385-2391","update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":174,"title":["Phylogenetic Relationships of\n            <i>Cryptosporidium<\/i>\n            Parasites Based on the 70-Kilodalton Heat Shock Protein (HSP70) Gene"],"prefix":"10.1128","volume":"66","author":[{"given":"Irshad M.","family":"Sulaiman","sequence":"first","affiliation":[{"name":"<!--label omitted: 1-->Division of Parasitic Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Public Health Services, U.S. Department of Health and Human Services, Atlanta, Georgia 30341,1 and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Una M.","family":"Morgan","sequence":"additional","affiliation":[{"name":"<!--label omitted: 2-->State Agricultural Biotechnological Centre, Murdoch University, Murdoch, Western Australia 6150, Australia2"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R. C. Andrew","family":"Thompson","sequence":"additional","affiliation":[{"name":"<!--label omitted: 2-->State Agricultural Biotechnological Centre, Murdoch University, Murdoch, Western Australia 6150, Australia2"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Altaf A.","family":"Lal","sequence":"additional","affiliation":[{"name":"<!--label omitted: 1-->Division of Parasitic Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Public Health Services, U.S. Department of Health and Human Services, Atlanta, Georgia 30341,1 and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lihua","family":"Xiao","sequence":"additional","affiliation":[{"name":"<!--label omitted: 1-->Division of Parasitic Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Public Health Services, U.S. Department of Health and Human Services, Atlanta, Georgia 30341,1 and"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"235","reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.2307\/3282084"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1017\/S0031182000077714"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.1093\/oxfordjournals.molbev.a026010"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.93.18.9651"},{"key":"e_1_3_2_6_2","doi-asserted-by":"publisher","DOI":"10.1128\/AEM.64.4.1454-1458.1998"},{"key":"e_1_3_2_7_2","first-page":"311","article-title":"Cryptosporidiosis in child care settings: a review of the literature and recommendations for prevention and control.","volume":"13","author":"Cordell R. 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