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Neither phosphate starvation, nutrient limitation, nor anaerobiosis was required to induce polyP formation. An increase in intracellular polyP was accompanied by a 4.5-fold increase in phosphate uptake from the medium and sixfold-higher levels of cellular polyphosphate kinase activity. This novel accumulation of polyP by\n            <jats:italic>C. humicola<\/jats:italic>\n            G-1 in response to acid pH provides further evidence as to the importance of polyP in the physiological adaptation of microbial cells during growth and development and in their response to environmental stresses.\n          <\/jats:p>","DOI":"10.1128\/aem.66.9.4068-4073.2000","type":"journal-article","created":{"date-parts":[[2002,7,27]],"date-time":"2002-07-27T09:56:57Z","timestamp":1027763817000},"page":"4068-4073","update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":68,"title":["Intracellular Accumulation of Polyphosphate by the Yeast\n            <i>Candida humicola<\/i>\n            G-1 in Response to Acid pH"],"prefix":"10.1128","volume":"66","author":[{"given":"John W.","family":"McGrath","sequence":"first","affiliation":[{"name":"School of Biology and Biochemistry1 and"},{"name":"QUESTOR Centre,2 The Queen's University of Belfast, Belfast, Northern Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John P.","family":"Quinn","sequence":"additional","affiliation":[{"name":"School of Biology and Biochemistry1 and"},{"name":"QUESTOR Centre,2 The Queen's University of Belfast, Belfast, Northern Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"235","reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9258(18)41708-5"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9258(18)54198-3"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.1128\/JB.180.7.1841-1847.1998"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/0167-4889(91)90173-U"},{"key":"e_1_3_2_6_2","doi-asserted-by":"publisher","DOI":"10.1128\/aem.62.4.1214-1219.1996"},{"key":"e_1_3_2_7_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF00245217"},{"key":"e_1_3_2_8_2","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.270.33.19377"},{"key":"e_1_3_2_9_2","doi-asserted-by":"publisher","DOI":"10.1016\/0005-2736(77)90341-8"},{"key":"e_1_3_2_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/0003-2697(76)90527-3"},{"key":"e_1_3_2_11_2","doi-asserted-by":"publisher","DOI":"10.1128\/jb.113.2.599-611.1973"},{"key":"e_1_3_2_12_2","doi-asserted-by":"publisher","DOI":"10.1128\/aem.61.12.4448-4453.1995"},{"key":"e_1_3_2_13_2","first-page":"178","article-title":"Energy reserve polymers in microorganisms","volume":"10","author":"Dawes E. 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