{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,4]],"date-time":"2026-10-04T10:27:16Z","timestamp":1791109636045,"version":"4.1.0"},"reference-count":35,"publisher":"American Society for Microbiology","issue":"1","license":[{"start":{"date-parts":[[2005,1,1]],"date-time":"2005-01-01T00:00:00Z","timestamp":1104537600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["Appl Environ Microbiol"],"published-print":{"date-parts":[[2005,1]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n          <jats:p>\n            Mutations designated\n            <jats:italic>gtaC<\/jats:italic>\n            and\n            <jats:italic>gtaE<\/jats:italic>\n            that affect \u03b1-phosphoglucomutase activity required for interconversion of glucose 6-phosphate and \u03b1-glucose 1-phosphate were mapped to the\n            <jats:italic>Bacillus subtilis pgcA<\/jats:italic>\n            (\n            <jats:italic>yhxB<\/jats:italic>\n            ) gene. Backcrossing of the two mutations into the 168 reference strain was accompanied by impaired \u03b1-phosphoglucomutase activity in the soluble cell extract fraction, altered colony and cell morphology, and resistance to phages \u03c629 and \u03c111. Altered cell morphology, reversible by additional magnesium ions, may be correlated with a deficiency in the membrane glycolipid. The deficiency in biofilm formation in\n            <jats:italic>gtaC<\/jats:italic>\n            and\n            <jats:italic>gtaE<\/jats:italic>\n            mutants may be attributed to an inability to synthesize UDP-glucose, an important intermediate in a number of cell envelope biosynthetic processes.\n          <\/jats:p>","DOI":"10.1128\/aem.71.1.39-45.2005","type":"journal-article","created":{"date-parts":[[2005,1,7]],"date-time":"2005-01-07T12:21:15Z","timestamp":1105100475000},"page":"39-45","update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":94,"title":["<i>Bacillus subtilis<\/i>\n            \u03b1-Phosphoglucomutase Is Required for Normal Cell Morphology and Biofilm Formation"],"prefix":"10.1128","volume":"71","author":[{"given":"Vladimir","family":"Lazarevic","sequence":"first","affiliation":[{"name":"D\u00e9partement de Microbiologie Fondamentale, B\u00c2timent de Biologie, Facult\u00e9 de Biologie et de M\u00e9decine, Universit\u00e9 de Lausanne, Lausanne, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Blazenka","family":"Soldo","sequence":"additional","affiliation":[{"name":"D\u00e9partement de Microbiologie Fondamentale, B\u00c2timent de Biologie, Facult\u00e9 de Biologie et de M\u00e9decine, Universit\u00e9 de Lausanne, Lausanne, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"No\u00ebl","family":"M\u00e9dico","sequence":"additional","affiliation":[{"name":"D\u00e9partement de Microbiologie Fondamentale, B\u00c2timent de Biologie, Facult\u00e9 de Biologie et de M\u00e9decine, Universit\u00e9 de Lausanne, Lausanne, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Harold","family":"Pooley","sequence":"additional","affiliation":[{"name":"D\u00e9partement de Microbiologie Fondamentale, B\u00c2timent de Biologie, Facult\u00e9 de Biologie et de M\u00e9decine, Universit\u00e9 de Lausanne, Lausanne, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sierd","family":"Bron","sequence":"additional","affiliation":[{"name":"Groningen Biomolecular Sciences and Biotechnology Institute, Department of Genetics, University of Groningen, Haren, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dimitri","family":"Karamata","sequence":"additional","affiliation":[{"name":"D\u00e9partement de Microbiologie Fondamentale, B\u00c2timent de Biologie, Facult\u00e9 de Biologie et de M\u00e9decine, Universit\u00e9 de Lausanne, Lausanne, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"235","reference":[{"key":"e_1_3_3_2_2","first-page":"425","year":"1993","unstructured":"Anagnostopoulos, C., P. 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