{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T01:20:44Z","timestamp":1790817644703,"version":"4.1.0"},"reference-count":34,"publisher":"American Society for Microbiology","issue":"8","license":[{"start":{"date-parts":[[2005,8,1]],"date-time":"2005-08-01T00:00:00Z","timestamp":1122854400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["Appl Environ Microbiol"],"published-print":{"date-parts":[[2005,8]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n          <jats:p>\n            Phosphorus is an essential component of macromolecules, like DNA, and central metabolic intermediates, such as sugar phosphates, and bacteria possess enzymes and control mechanisms that provide an optimal supply of phosphorus from the environment. UDP-sugar hydrolases and 5\u2032 nucleotidases may play roles in signal transduction, as they do in mammals, in nucleotide salvage, as demonstrated for UshA of\n            <jats:italic>Escherichia coli<\/jats:italic>\n            , or in phosphorus metabolism. The\n            <jats:italic>Corynebacterium glutamicum<\/jats:italic>\n            gene\n            <jats:italic>ushA<\/jats:italic>\n            was found to encode a secreted enzyme which is active as a 5\u2032 nucleotidase and a UDP-sugar hydrolase. This enzyme was synthesized and secreted into the medium when\n            <jats:italic>C. glutamicum<\/jats:italic>\n            was starved for inorganic phosphate. UshA was required for growth of\n            <jats:italic>C. glutamicum<\/jats:italic>\n            on AMP and UDP-glucose as sole sources of phosphorus. Thus, in contrast to UshA from\n            <jats:italic>E. coli<\/jats:italic>\n            ,\n            <jats:italic>C. glutamicum<\/jats:italic>\n            UshA is an important component of the phosphate starvation response of this species and is necessary to access nucleotides and related compounds as sources of phosphorus.\n          <\/jats:p>","DOI":"10.1128\/aem.71.8.4339-4344.2005","type":"journal-article","created":{"date-parts":[[2005,8,5]],"date-time":"2005-08-05T21:53:12Z","timestamp":1123278792000},"page":"4339-4344","update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":50,"title":["Phosphate Starvation-Inducible Gene\n            <i>ushA<\/i>\n            Encodes a 5\u2032 Nucleotidase Required for Growth of\n            <i>Corynebacterium glutamicum<\/i>\n            on Media with Nucleotides as the Phosphorus Source"],"prefix":"10.1128","volume":"71","author":[{"given":"Doris","family":"Rittmann","sequence":"first","affiliation":[{"name":"Institute of Biotechnology 1, Research Center Juelich, D-52428 Juelich, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ulrike","family":"Sorger-Herrmann","sequence":"additional","affiliation":[{"name":"Institute of Biotechnology 1, Research Center Juelich, D-52428 Juelich, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Volker F.","family":"Wendisch","sequence":"additional","affiliation":[{"name":"Institute of Biotechnology 1, Research Center Juelich, D-52428 Juelich, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"235","reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1128\/JB.182.16.4478-4490.2000"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.pp.24.060173.001301"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/14.10.4325"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.1128\/jb.178.13.3926-3933.1996"},{"key":"e_1_3_2_6_2","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1111\/j.1574-6968.1993.tb06588.x","volume":"114","year":"1993","unstructured":"Edwards, C. 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