{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T11:25:36Z","timestamp":1791285936293,"version":"4.1.0"},"reference-count":36,"publisher":"American Society for Microbiology","issue":"1","license":[{"start":{"date-parts":[[2006,1,1]],"date-time":"2006-01-01T00:00:00Z","timestamp":1136073600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["Appl Environ Microbiol"],"published-print":{"date-parts":[[2006,1]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n          <jats:p>\n            Invasion of intestinal epithelial cells by\n            <jats:italic>Salmonella enterica<\/jats:italic>\n            is decreased after exposure to butyric acid. To understand the molecular mechanisms of this phenomenon, a comparative transcriptomic analysis of\n            <jats:italic>Salmonella enterica<\/jats:italic>\n            serovar Enteritidis and\n            <jats:italic>Salmonella enterica<\/jats:italic>\n            serovar Typhimurium grown in medium supplemented with butyrate was performed. We found that butyrate down-regulated the expression of 19 genes common to both serovars by a factor of twofold or more, and 17 of these genes localized to the\n            <jats:italic>Salmonella<\/jats:italic>\n            pathogenicity island 1 (SPI1). These included the SPI1 regulatory genes\n            <jats:italic>hilD<\/jats:italic>\n            and\n            <jats:italic>invF<\/jats:italic>\n            . Of the remaining two genes,\n            <jats:italic>ampH<\/jats:italic>\n            has 91% homology to an\n            <jats:italic>Escherichia coli<\/jats:italic>\n            penicillin-binding protein and\n            <jats:italic>sopE2<\/jats:italic>\n            encodes a type III-secreted effector protein associated with invasion but located at a separate site on the chromosome from SPI1.\n          <\/jats:p>","DOI":"10.1128\/aem.72.1.946-949.2006","type":"journal-article","created":{"date-parts":[[2006,1,3]],"date-time":"2006-01-03T20:33:36Z","timestamp":1136320416000},"page":"946-949","update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":340,"title":["Butyrate Specifically Down-Regulates\n            <i>Salmonella<\/i>\n            Pathogenicity Island 1 Gene Expression"],"prefix":"10.1128","volume":"72","author":[{"given":"I.","family":"Gantois","sequence":"first","affiliation":[{"name":"Department of Pathology, Bacteriology and Avian Diseases, Research Group Veterinary Public Health and Zoonoses, Faculty of Veterinary Medicine, Ghent University, Salisburylaan 133, B-9820 Merelbeke, Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R.","family":"Ducatelle","sequence":"additional","affiliation":[{"name":"Department of Pathology, Bacteriology and Avian Diseases, Research Group Veterinary Public Health and Zoonoses, Faculty of Veterinary Medicine, Ghent University, Salisburylaan 133, B-9820 Merelbeke, Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"F.","family":"Pasmans","sequence":"additional","affiliation":[{"name":"Department of Pathology, Bacteriology and Avian Diseases, Research Group Veterinary Public Health and Zoonoses, Faculty of Veterinary Medicine, Ghent University, Salisburylaan 133, B-9820 Merelbeke, Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"F.","family":"Haesebrouck","sequence":"additional","affiliation":[{"name":"Department of Pathology, Bacteriology and Avian Diseases, Research Group Veterinary Public Health and Zoonoses, Faculty of Veterinary Medicine, Ghent University, Salisburylaan 133, B-9820 Merelbeke, Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"I.","family":"Hautefort","sequence":"additional","affiliation":[{"name":"Molecular Microbiology Group, Institute of Food Research, Norwich Research Park, Norwich NR4 7UA, United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Thompson","sequence":"additional","affiliation":[{"name":"Molecular Microbiology Group, Institute of Food Research, Norwich Research Park, Norwich NR4 7UA, United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J. 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