{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,31]],"date-time":"2025-12-31T07:36:00Z","timestamp":1767166560493,"version":"build-2238731810"},"reference-count":0,"publisher":"American Society for Microbiology","issue":"3","license":[{"start":{"date-parts":[[1967,5,1]],"date-time":"1967-05-01T00:00:00Z","timestamp":-84326400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["Appl Microbiol"],"published-print":{"date-parts":[[1967,5]]},"abstract":"<jats:p>\n                    The effects of virus input multiplicity and of tissue cell concentration upon the growth of Rift Valley fever virus in L cells (Earle) were determined. The titers obtained in suspension cultures with cells obtained from two separate laboratories were significantly different. With both monolayer culture and suspension culture systems, a virus input multiplicity of 2.5 resulted in the greatest proliferation of virus. Optimal viral yields were obtained in suspension cultures containing 4 \u00d7 10\n                    <jats:sup>5<\/jats:sup>\n                    tissue cells per ml of suspension.\n                  <\/jats:p>","DOI":"10.1128\/am.15.3.594-596.1967","type":"journal-article","created":{"date-parts":[[2020,12,5]],"date-time":"2020-12-05T04:41:41Z","timestamp":1607143301000},"page":"594-596","update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":3,"title":["Effect of Imput Multiplicity and Tissue Cell Concentration on Growth of Rift Valley Fever Virus"],"prefix":"10.1128","volume":"15","author":[{"given":"Michael D.","family":"Orlando","sequence":"first","affiliation":[{"name":"Department of the Army, Fort Detrick, Frederick, Maryland 21701"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Richard D.","family":"DeLauter","sequence":"additional","affiliation":[{"name":"Department of the Army, Fort Detrick, Frederick, Maryland 21701"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jean M.","family":"Riley","sequence":"additional","affiliation":[{"name":"Department of the Army, Fort Detrick, Frederick, Maryland 21701"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"235","container-title":["Applied Microbiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/am.15.3.594-596.1967","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/am.15.3.594-596.1967","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,2,23]],"date-time":"2022-02-23T02:45:12Z","timestamp":1645584312000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.asm.org\/doi\/10.1128\/am.15.3.594-596.1967"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1967,5]]},"references-count":0,"aliases":["10.1128\/aem.15.3.594-596.1967"],"journal-issue":{"issue":"3","published-print":{"date-parts":[[1967,5]]}},"alternative-id":["10.1128\/am.15.3.594-596.1967"],"URL":"https:\/\/doi.org\/10.1128\/am.15.3.594-596.1967","relation":{},"ISSN":["0003-6919"],"issn-type":[{"value":"0003-6919","type":"print"}],"subject":[],"published":{"date-parts":[[1967,5]]},"assertion":[{"value":"1967-05-01","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}