{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,31]],"date-time":"2025-12-31T07:44:57Z","timestamp":1767167097652,"version":"build-2238731810"},"reference-count":0,"publisher":"American Society for Microbiology","issue":"3","license":[{"start":{"date-parts":[[1969,3,1]],"date-time":"1969-03-01T00:00:00Z","timestamp":-26438400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["Appl Microbiol"],"published-print":{"date-parts":[[1969,3]]},"abstract":"<jats:p>Methods for the elimination of salmonellae from selected powdered pharmaceuticals of animal glandular origin were studied. Terminal heat treatment under carefully controlled conditions was effective for pancreatin\u2014a powder containing proteolytic, amylolytic, and lipolytic enzymes prepared from hog pancreas glands. Use of this method resulted in a significant reduction in the number of salmonella-positive batches and also reduced the testing procedures required to confirm the absence of viable salmonellae among the majority of samples tested. Powders such as stomach substance and thyroid, in which the biological activity is not enzyme in nature, were treated successfully with acidified organic solvents. Other methods were investigated but were not suitable because of a deleterious effect on the biological activity or physical properties of the product or an inability to effect salmonella elimination.<\/jats:p>","DOI":"10.1128\/am.17.3.344-346.1969","type":"journal-article","created":{"date-parts":[[2020,12,5]],"date-time":"2020-12-05T03:01:53Z","timestamp":1607137313000},"page":"344-346","update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":2,"title":["Elimination of Salmonellae from Animal Glandular Products"],"prefix":"10.1128","volume":"17","author":[{"given":"Conrad W.","family":"De Fiebre","sequence":"first","affiliation":[{"name":"The Wilson Laboratories, Chicago, Illinois 60609"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kenneth T.","family":"Burck","sequence":"additional","affiliation":[{"name":"The Wilson Laboratories, Chicago, Illinois 60609"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David","family":"Feldman","sequence":"additional","affiliation":[{"name":"The Wilson Laboratories, Chicago, Illinois 60609"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"235","container-title":["Applied Microbiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/am.17.3.344-346.1969","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/am.17.3.344-346.1969","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,2,23]],"date-time":"2022-02-23T04:08:01Z","timestamp":1645589281000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.asm.org\/doi\/10.1128\/am.17.3.344-346.1969"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1969,3]]},"references-count":0,"aliases":["10.1128\/aem.17.3.344-346.1969"],"journal-issue":{"issue":"3","published-print":{"date-parts":[[1969,3]]}},"alternative-id":["10.1128\/am.17.3.344-346.1969"],"URL":"https:\/\/doi.org\/10.1128\/am.17.3.344-346.1969","relation":{},"ISSN":["0003-6919"],"issn-type":[{"value":"0003-6919","type":"print"}],"subject":[],"published":{"date-parts":[[1969,3]]},"assertion":[{"value":"1969-03-01","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}