{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,31]],"date-time":"2025-12-31T07:45:27Z","timestamp":1767167127967,"version":"build-2238731810"},"reference-count":0,"publisher":"American Society for Microbiology","issue":"3","license":[{"start":{"date-parts":[[1970,3,1]],"date-time":"1970-03-01T00:00:00Z","timestamp":5097600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["Appl Microbiol"],"published-print":{"date-parts":[[1970,3]]},"abstract":"<jats:p>\n                    An obligately anaerobic, gram-negative microorganism identified as a\n                    <jats:italic>Sphaerophorus<\/jats:italic>\n                    species was recovered from the fecal material of two cancer (chronic myelogenous leukemia and idiopathic thrombocythemia) patients receiving cobalt radiation therapy. The organism, isolated on sheep blood-agar, exhibited extreme pleomorphism (rods, filaments, and spheroids) and was a major component of the anaerobic fecal microflora. In one patient the numbers of\n                    <jats:italic>Sphaerophorus<\/jats:italic>\n                    species (designated as isolate 6-13-68),\n                    <jats:italic>Bacteroides<\/jats:italic>\n                    species, and\n                    <jats:italic>Clostridium perfringens<\/jats:italic>\n                    declined after irradiation; however, they were stable in this same patient after a second therapeutic dose of radiation. The numbers of anaerobes in the other patient remained fairly consistent after radiation. The biochemical and morphological characteristics and carbohydrate fermentation reactions of isolate 6-13-68 most closely resembled those of\n                    <jats:italic>Sphaerophorus ridiculosis<\/jats:italic>\n                    .\n                  <\/jats:p>","DOI":"10.1128\/am.19.3.458-462.1970","type":"journal-article","created":{"date-parts":[[2020,12,5]],"date-time":"2020-12-05T03:41:37Z","timestamp":1607139697000},"page":"458-462","update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":3,"title":["Unusual\n                    <i>Sphaerophorus<\/i>\n                    Species from the Large Intestine of Man"],"prefix":"10.1128","volume":"19","author":[{"given":"Ted A.","family":"Pearson","sequence":"first","affiliation":[{"name":"Medical Division, Oak Ridge Associated Universities, Oak Ridge, Tennessee 37830"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Edward","family":"Balish","sequence":"additional","affiliation":[{"name":"Medical Division, Oak Ridge Associated Universities, Oak Ridge, Tennessee 37830"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"235","container-title":["Applied Microbiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/am.19.3.458-462.1970","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/am.19.3.458-462.1970","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,2,23]],"date-time":"2022-02-23T05:11:24Z","timestamp":1645593084000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.asm.org\/doi\/10.1128\/am.19.3.458-462.1970"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1970,3]]},"references-count":0,"aliases":["10.1128\/aem.19.3.458-462.1970"],"journal-issue":{"issue":"3","published-print":{"date-parts":[[1970,3]]}},"alternative-id":["10.1128\/am.19.3.458-462.1970"],"URL":"https:\/\/doi.org\/10.1128\/am.19.3.458-462.1970","relation":{},"ISSN":["0003-6919"],"issn-type":[{"value":"0003-6919","type":"print"}],"subject":[],"published":{"date-parts":[[1970,3]]},"assertion":[{"value":"1970-03-01","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}