{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,31]],"date-time":"2025-12-31T07:36:56Z","timestamp":1767166616548,"version":"build-2238731810"},"reference-count":0,"publisher":"American Society for Microbiology","issue":"5","license":[{"start":{"date-parts":[[1972,11,1]],"date-time":"1972-11-01T00:00:00Z","timestamp":89424000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["Appl Microbiol"],"published-print":{"date-parts":[[1972,11]]},"abstract":"<jats:p>\n                    The relative capacity of several types of human cells and tissue to produce interferon was studied. Types of cells and tissue included were fibroblasts from embryos, foreskins, and biopsied skins; amnion cells; peripheral leukocytes; established lymphoid cell lines; established heteroploid cell lines; and chorioamniotic membrane. When Newcastle disease virus was used as the inducer, fibroblasts and amnion cells produced more interferon per 10\n                    <jats:sup>6<\/jats:sup>\n                    cells than leukocytes, lymphoid cells, and heteroploid cells. Only minor variations in interferon-producing capacity were observed among fibroblasts from 36 persons. Culture passage level, cell concentration, and inducer were factors that significantly affected interferon production.\n                  <\/jats:p>","DOI":"10.1128\/am.24.5.735-741.1972","type":"journal-article","created":{"date-parts":[[2020,12,5]],"date-time":"2020-12-05T04:23:33Z","timestamp":1607142213000},"page":"735-741","update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":5,"title":["Interferon Production by Human Cells In Vitro"],"prefix":"10.1128","volume":"24","author":[{"given":"Celsa A.","family":"Spina","sequence":"first","affiliation":[{"name":"Department of Medical Microbiology, University of California, Davis, California 95616"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R. Shihman","family":"Chang","sequence":"additional","affiliation":[{"name":"Department of Medical Microbiology, University of California, Davis, California 95616"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L.","family":"Mishra","sequence":"additional","affiliation":[{"name":"Department of Medical Microbiology, University of California, Davis, California 95616"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H. Dean","family":"Golden","sequence":"additional","affiliation":[{"name":"Department of Medical Microbiology, University of California, Davis, California 95616"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"235","container-title":["Applied Microbiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/am.24.5.735-741.1972","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/am.24.5.735-741.1972","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,2,23]],"date-time":"2022-02-23T08:27:58Z","timestamp":1645604878000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.asm.org\/doi\/10.1128\/am.24.5.735-741.1972"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1972,11]]},"references-count":0,"aliases":["10.1128\/aem.24.5.735-741.1972"],"journal-issue":{"issue":"5","published-print":{"date-parts":[[1972,11]]}},"alternative-id":["10.1128\/am.24.5.735-741.1972"],"URL":"https:\/\/doi.org\/10.1128\/am.24.5.735-741.1972","relation":{},"ISSN":["0003-6919"],"issn-type":[{"value":"0003-6919","type":"print"}],"subject":[],"published":{"date-parts":[[1972,11]]},"assertion":[{"value":"1972-11-01","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}