{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,31]],"date-time":"2025-12-31T07:46:30Z","timestamp":1767167190542,"version":"build-2238731810"},"reference-count":0,"publisher":"American Society for Microbiology","issue":"5","license":[{"start":{"date-parts":[[1972,11,1]],"date-time":"1972-11-01T00:00:00Z","timestamp":89424000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["Appl Microbiol"],"published-print":{"date-parts":[[1972,11]]},"abstract":"<jats:p>\n                    A method is described by which a soluble antigen was prepared from the yeast phase of\n                    <jats:italic>Histoplasma capsulatum<\/jats:italic>\n                    . This soluble preparation had a specificity greater than that of whole-cell yeast-phase antigens. In complement fixation tests with sera from human cases of histoplasmosis, blastomycosis, and coccidioidomycosis, the soluble antigen reacted in 12.1% of 141 tests with heterologous sera, whereas conventional whole-cell yeast antigens reacted in 47.3% of 91 tests with heterologous sera. The reactivities of the two types of antigens with homologous sera were essentially the same.\n                  <\/jats:p>","DOI":"10.1128\/am.24.5.841-843.1972","type":"journal-article","created":{"date-parts":[[2020,12,5]],"date-time":"2020-12-05T03:39:15Z","timestamp":1607139555000},"page":"841-843","update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":11,"title":["Isolation of a New Soluble Antigen from the Yeast Phase of\n                    <i>Histoplasma capsulatum<\/i>"],"prefix":"10.1128","volume":"24","author":[{"given":"Michael W.","family":"Reeves","sequence":"first","affiliation":[{"name":"Research and Development Unit, Biological Reagents Section and Fungus Immunology Unit, Mycology Section, Center for Disease Control, Health Services and Mental Health Administration, Atlanta, Georgia 30333"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Leo","family":"Pine","sequence":"additional","affiliation":[{"name":"Research and Development Unit, Biological Reagents Section and Fungus Immunology Unit, Mycology Section, Center for Disease Control, Health Services and Mental Health Administration, Atlanta, Georgia 30333"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Leo","family":"Kaufman","sequence":"additional","affiliation":[{"name":"Research and Development Unit, Biological Reagents Section and Fungus Immunology Unit, Mycology Section, Center for Disease Control, Health Services and Mental Health Administration, Atlanta, Georgia 30333"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David","family":"McLaughlin","sequence":"additional","affiliation":[{"name":"Research and Development Unit, Biological Reagents Section and Fungus Immunology Unit, Mycology Section, Center for Disease Control, Health Services and Mental Health Administration, Atlanta, Georgia 30333"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"235","container-title":["Applied Microbiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/am.24.5.841-843.1972","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/am.24.5.841-843.1972","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,2,23]],"date-time":"2022-02-23T08:28:15Z","timestamp":1645604895000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.asm.org\/doi\/10.1128\/am.24.5.841-843.1972"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1972,11]]},"references-count":0,"aliases":["10.1128\/aem.24.5.841-843.1972"],"journal-issue":{"issue":"5","published-print":{"date-parts":[[1972,11]]}},"alternative-id":["10.1128\/am.24.5.841-843.1972"],"URL":"https:\/\/doi.org\/10.1128\/am.24.5.841-843.1972","relation":{},"ISSN":["0003-6919"],"issn-type":[{"value":"0003-6919","type":"print"}],"subject":[],"published":{"date-parts":[[1972,11]]},"assertion":[{"value":"1972-11-01","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}